DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and ceh-48

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_501046.1	Gene:	ceh-48 / 182756	WormBaseID:	WBGene00015934	Length:	459	Species:	Caenorhabditis elegans

Alignment Length:	428	Identity:	95/428 - (22%)
Similarity:	154/428 - (35%)	Gaps:	112/428 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1199 SSLEHSAGSSSCSKDG---ERDDAYPSSLH----------------------GRKSEGGG----- 1233
            |.:.|:..|.....||   :.||..|.|.|                      ||.|....
Worm    19 SPIHHAILSMDDEVDGNCDDVDDISPESHHDNHFIDFTDDLVVQTERNLSKKGRTSNRNARQGYD 83

  Fly  1234 -----TPAPPAPPSGPGTGAGAP---PTAAP----PTGGASS-----------------NSAAPS 1269
                 |...|.||....|.....   |:.:|    ||...||                 :|::||
Worm    84 NYATLTNLQPLPPISTVTSKSTKVQRPSPSPNFYFPTSSNSSYDMKYEEEEDDCEGITHSSSSPS 148

  Fly  1270 PLSN---SILPPALSSQGEEFAATASPLQRMASITNS---LITQPPVTPHHSTPQRP----TKAV 1324
            ..||   .:..|..:|..:.|..|.......::|.||   .|.:  :....||.:.|    ..|:
Worm   149 DFSNHGTDLNHPFSASSFDSFDVTTVSTTATSTIMNSTDKFIAR--IQEADSTTKSPKGTSPAAL 211

  Fly  1325 LPPITQQQFDMFNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLARPKPWHMLTQ 1389
            :....::.||....|||:::..::...|.:|||.|.:|.|.||..|||::||||..||||..| :
Worm   212 MHGHCEEDFDDGEELNTKELALQIAAELKRYSIPQAIFAERVLCRSQGTLSDLLRNPKPWSKL-K 275

  Fly  1390 KGREPFIRMKMFLEDENAVHKLVASQYKIAPEKLMRTGSYSGSPQMPQGLASKMQAASLPMQKMM 1454
            .|||.|.||..:||:.....   .|..::|..|.....:...||||
Worm   276 SGRETFRRMAKWLEEPEFQR---MSALRLAACKRKEEHTTPNSPQM------------------- 318

  Fly  1455 SELKLQEPAQAQHLMQQMQAAAMSAAMQQQQVAQAQQQAQQAQQAQ-------------QHLQQQ 1506
                 ..|.:.:.:...:|...:.|..::.:....:.|...:||..             :.....
Worm   319 -----VVPKKTRLVFSDIQRRTLQAIFRETKRPSREMQITISQQLNLDPTTVANFFMNARRRGHD 378

  Fly  1507 AQQHLQQQQHLAQQQHPHQQHHQAAAAAAALHHQSMLL 1544
            .:|...:.:..:::...|.:|..::::|::....||.|
Worm   379 LKQETSESEERSEEPSIHFEHSASSSSASSSSSSSMQL 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527	32/75 (43%)
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475
ceh-48	NP_501046.1	CUT	222..296	CDD:280527	32/77 (42%)
ceh-48	NP_501046.1	HOX	321..375	CDD:197696	6/53 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910