DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ct and dsc-1

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_510497.1	Gene:	dsc-1 / 181599	WormBaseID:	WBGene00001096	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	270	Identity:	65/270 - (24%)
Similarity:	91/270 - (33%)	Gaps:	66/270 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1549 LPPQHAI------SLPPSAGGAQPGGPGGNQG-------SSNPSNSEKKPMLMPVHGTNAMRSLH 1600
            ||...|:      |:||...|||...|..|.|       |...|....:|.....|  |...:||
Worm    20 LPKSEALSVTTDFSVPPVQQGAQQFHPPRNLGPQLARRWSCGDSQHADEPPASYYH--NLGVALH 82

  Fly  1601 QH--MSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWH 1663
            .|  ||...|        |...|..|.:.....|:..||         |.|.|..:.:....| |
Worm    83 NHFQMSNQHY--------LSDFDCPTTVSPISSAHETGQ---------LPQLSPYDHIGNQDP-H 129

  Fly  1664 MLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTS 1728
            |.|     |.......:.|.:..|      |..|..|      .||       ..::..|....|
Worm   130 MFS-----PHAYGNSMIPDNSYFE------NASRSIS------APN-------VGNSTLNPSLMS 170

  Fly  1729 SPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWF 1793
            |....|.|.       .::.|..|:|.|...|..:|....||:....:::|:.|.:....||.||
Worm   171 SDNAQSCGG-------RRRFRTNFTELQSTFLEDSFKESHYPDHKAKKYMADFLKIPEDRITVWF 228

  Fly  1794 HNHRMRLKQQ 1803
            .|.|.:.:::
Worm   229 QNRRAKWRRK 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	16/73 (22%)
		Homeobox	1749..1801	CDD:278475	16/51 (31%)
dsc-1	NP_510497.1	Homeobox	184..236	CDD:278475	16/51 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910