DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and ttx-1

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001024212.1	Gene:	ttx-1 / 180313	WormBaseID:	WBGene00006652	Length:	391	Species:	Caenorhabditis elegans

Alignment Length:	285	Identity:	63/285 - (22%)
Similarity:	105/285 - (36%)	Gaps:	51/285 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1542 MLLTSPGLPPQHAISLPPSAGGAQPG-GPGGNQGSS--NPSNSEKKPMLMPVHGTNAMR-----S 1598
            |.|||...|....:.|..|...:..| |.|||.||:  |..|....|.|.   ||.|.:     |
Worm     1 MSLTSSSAPSDSIVELIQSQNLSGSGSGTGGNTGSTTMNSGNFIPTPSLT---GTGASQSSGSAS 62

  Fly  1599 LHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWH 1663
            ....:||...:.......:|.:|.|:.:.:.                 |:||:     :...|:.
Worm    63 SGNFVSPDETDTKPSPSLMDHNDPTSSLSQQ-----------------LAQGA-----TLTSPYS 105

  Fly  1664 MLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQ--------------QDNS 1714
            ..::.....:.::.. :|...||.....:......|...::|..|..              |.|.
Worm   106 TTTVDPSSLYFQLSP-MSYIPNVSSATTVAAANMSAYFNQKSAYPTSHLGFPSNVGSHSFLQSNM 169

  Fly  1715 SDTSSNDTNDFYTSSPGPGSVGSGVGG-APPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFL 1778
            ...||  .:|..|::.|..|..:...| :...:::|..|:..|.|.|...|....||::...|.:
Worm   170 YIPSS--LSDCPTATMGSMSWNANQPGFSRKQRRERTTFTRNQLEILESYFVKTRYPDIFMREDM 232

  Fly  1779 ANELGLATRTITNWFHNHRMRLKQQ 1803
            |:::.|....:..||.|.|.:.:||
Worm   233 AHKIQLPESRVQVWFKNRRAKARQQ 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	10/73 (14%)
		Homeobox	1749..1801	CDD:278475	15/51 (29%)
ttx-1	NP_001024212.1	Homeobox	203..256	CDD:365835	15/52 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910