DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and pxl-1

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001021185.2	Gene:	pxl-1 / 175831	WormBaseID:	WBGene00016197	Length:	413	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	39/226 - (17%)
Similarity:	82/226 - (36%)	Gaps:	56/226 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1450 MQKMMSELKLQEPAQAQHLMQQMQAAAMSAAMQQQQVAQAQQQAQQAQQAQQHLQQQA------- 1507
            ::.::|:|        ||..:.::.|.:|     .:.:|::...:|:...|.:|..|:
Worm    15 LEALLSDL--------QHTTEVLRRAHIS-----DRRSQSRDDFEQSYDLQGNLNTQSVSNGNIT 66

  Fly  1508 -----QQHLQQQQHLAQQQHPHQQHHQAAAAAAALHHQSMLLTSPGLPPQHAISLPPSAGGAQPG 1567
                 ::..:.:.:...|:..::...:......:......||:....||..|.|...|.     |
Worm    67 TSPYKRRSSEGKDYSKSQERIYENESRLNPPVYSRPSVQSLLSQVEEPPIRASSSRKSL-----G 126

  Fly  1568 GPGGNQGSSNPSNSEKKPMLMPVHGTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLA 1632
            .|...|..|:..::.:.|...|:|..:.:.:::..:|             ..|.:.|..|....|
Worm   127 PPSQAQSYSDVRSNGRSPSRDPLHSDSMIGTMNGELS-------------SKHGVNTIPKGDCAA 178

  Fly  1633 NNIGQKIFGEAVLGLSQGSVSELLSKPKPWH 1663
              .|:.|.|:.|:.|.           |.||
Worm   179 --CGKPIIGQVVIALG-----------KMWH 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	12/48 (25%)
		Homeobox	1749..1801	CDD:278475
pxl-1	NP_001021185.2	LIM1_Leupaxin	174..228	CDD:188790	9/36 (25%)
		LIM	235..290	CDD:278823
		LIM3_Paxillin_like	294..346	CDD:188724
		LIM4_Paxillin_like	353..404	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910