DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and AgaP_AGAP010209

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_319393.4	Gene:	AgaP_AGAP010209 / 1279631	VectorBaseID:	AGAP010209	Length:	451	Species:	Anopheles gambiae

Alignment Length:	297	Identity:	66/297 - (22%)
Similarity:	101/297 - (34%)	Gaps:	81/297 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1693 KNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGS----VGSGVGGAPPSKKQRV--L 1751
            |.||| ..|..:.|...|   ||.:::|..:....|....||    .|.|..|....|..||  :
Mosquito   190 KQERR-IQKNNKHTNKRQ---SSPSNANVVHVNQNSGSESGSHKSLRGKGPSGPSDGKPTRVRTV 250

  Fly  1752 FSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMRLKQQVPHGPAGQDNPIP 1816
            .:|:|...||..:..:|.|:....|.|....||:.|.|..||.|.|.:.|::.
Mosquito   251 LNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKT------------ 303

  Fly  1817 SRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAPIPYPPYFAAAAILGRSLAGIPGAAAAA- 1880
                        :|.::.:||. .|..|...||.|.|:     .|::.:...|...:.|....|
Mosquito   304 ------------IQMKLQMQQE-KEGRKLGYGMQGIPM-----VASSPVRHDSPLNLHGLEVTAY 350

  Fly  1881 -------GAAAAAAAVGASGGDELQALNQAFK---EQMSGLDL-------------SMPTLKRER 1922
                   ...|..:.:.::|  .:.....||:   .||.|.|:             .||.:..:
Mosquito   351 QPPWKALSDFALHSDLDSNG--SINTHTPAFQHLVNQMHGYDVGNGGGGGPGGGPGGMPPMPGQ- 412

  Fly  1923 SDDYQDDLELEGGGH--NLSDNESLEGQEPEDKTTDY 1957
                        ||.  .:..:..|.|....|.|..|
Mosquito   413 ------------GGQVPPIGSHMDLSGHHHPDSTDSY 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475	18/53 (34%)
AgaP_AGAP010209	XP_319393.4	LIM1_Isl	56..110	CDD:188752
		LIM2_Isl	118..173	CDD:188760
		COG5576	196..>318	CDD:227863	36/149 (24%)
		HOX	244..300	CDD:197696	18/55 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910