DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ct and AgaP_AGAP005138

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_314022.4	Gene:	AgaP_AGAP005138 / 1274816	VectorBaseID:	AGAP005138	Length:	456	Species:	Anopheles gambiae

Alignment Length:	460	Identity:	90/460 - (19%)
Similarity:	135/460 - (29%)	Gaps:	182/460 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   697 QQQPNSGSNSNPASNDHHHGHHLHGHGLLHPSSAHHLHHQTTESNSNSSTPTAAGNNNGSNNSSS 761
            |.:|::|.:.  .:|:|.:|             .:.::.....:..|::|| ..|...|||:|.|
Mosquito    16 QPEPDTGGSL--TNNEHANG-------------TNGVNIGANVTAGNTATP-GPGMIPGSNSSCS 64

  Fly   762 -----NTNANSTAQLAASLAS-----TLNG--TKSLMQEDSNGLAAVAMAA-------------H 801
                 .|....|.|.:...:|     |..|  |.:.:.|....|.|..|.|             |
Mosquito    65 AKTPITTTGTPTLQPSVPRSSQQAYTTTGGSVTAATLAEGQRLLLAAVMTAGSGNGEIGAQQQQH 129

  Fly   802 AQHAAALGPGFLPGL----------------------------PAFQFAAAQV-----AAGGDGR 833
            ...:...||..|.||                            ...|..:..:     ....||:
Mosquito   130 GDGSGGDGPEHLAGLLGTSLCGQCCGPICDRYIMKVVDITYHERCLQCTSCSIRLMHSCFMRDGK 194

  Fly   834 GHYRFADSELQLPPGASMAGRLGESL---------------------------IPKGD------- 864
            .:.||....|.   |.:.....||.:                           :.|||
Mosquito   195 LYCRFDYERLY---GRNRCLGCGEKIGADELVMRALDNVFHLKCFICVVCGVRLQKGDQYVIKQS 256

  Fly   865 -----PMEAKLQEMLR-YNMDKYA-----NQALDTLHISRRVRELLSVHNIGQRLFAKYILGLSQ 918
                 |...|..||.: |:.|.|.     ...:|.....:|.|.:|:..   ||...|....:|
Mosquito   257 QLFCRPDYEKEVEMFQGYSYDDYCCDDMFQTRIDGRRGPKRPRTILTTQ---QRRAFKASFDIS- 317

  Fly   919 GTVSELLSKPKPWDKLTEKGRDSYRKMHAWACDDNAVMLLKSLIPK---KDSGLPQYAGRGAGGA 980
                     |||..|:.|          ..|.|....:.:...|.|   |:.|...:.|.|.|.:
Mosquito   318 ---------PKPCRKIRE----------GLAKDTGLSIRIVQKIQKKQLKEGGKSSHHGGGNGSS 363

  Fly   981 G----------GDDSMSEDRIAHILSEASSLMKQSSVAQHREQERRSHGGEDSHSNEDSKSPPQS 1035
            |          |:||..|      ||:..|.:                ||:.|...:|..|  ..
Mosquito   364 GGNKNHNGNGKGNDSQEE------LSDNESAV----------------GGKLSLRIKDENS--SK 404

  Fly  1036 CTSPF 1040
            ||:.|
Mosquito   405 CTNCF 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527	15/68 (22%)
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475
AgaP_AGAP005138	XP_314022.4	LIM	150..202	CDD:295319	5/51 (10%)
		LIM	210..264	CDD:295319	6/53 (11%)
		homeodomain	296..>341	CDD:238039	14/67 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910