DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and AgaP_AGAP011134

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_309513.3	Gene:	AgaP_AGAP011134 / 1270792	VectorBaseID:	AGAP011134	Length:	501	Species:	Anopheles gambiae

Alignment Length:	323	Identity:	72/323 - (22%)
Similarity:	93/323 - (28%)	Gaps:	113/323 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly  1610 MAALTQDLDTHDITTKIKEALLANNIGQKI------FGEAVLGLSQGSVSELLSKPKPWHMLSIK 1668
            |.:.::|.|..|   :::..:||..:....      .|:..||.|..||..:.:..|..|..|.:
Mosquito   155 MGSASEDEDEED---QMRPGVLAGLVSGGAGAAGLHHGDGPLGASDLSVQSMSTDSKTGHDDSDQ 216

  Fly  1669 GR---EPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSP 1730
            |.   :|..|                               |.:|.:|.|            ...
Mosquito   217 GSLDGDPDCR-------------------------------GDSQAENKS------------PDD 238

  Fly  1731 GPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHN 1795
            |.||...|         .|.....:|.|.|:.||:..|.|.....|.||.|.||..|.|..||.|
Mosquito   239 GAGSKRRG---------PRTTIKAKQLEVLKNAFSQTPKPTRHIREQLAKETGLPMRVIQVWFQN 294

  Fly  1796 HR---MRLKQQVPHG-------------------PAGQDNPIPSRESTSATPFDPVQFRILLQQR 1838
            .|   .||||....|                   |.|.|.|        ..|:....
Mosquito   295 KRSKERRLKQLTSMGRGPFFGGARKMRGFPMNLSPGGLDEP--------GFPYFAAD-------- 343

  Fly  1839 LLELHKERMGMSGAPI-PY-PPYFAAAAILGRSLAGIPGA-----AAAAGAAAAAAAVGASGG 1894
                .|...|..|.|. |: .|:|......|....|.||.     ....|....|...|..||
Mosquito   344 ----GKFDFGYGGPPFHPHDAPFFGGHPGAGPMPFGGPGGPMDHPIPMVGDFGMAGPDGGPGG 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	17/82 (21%)
		Homeobox	1749..1801	CDD:278475	21/54 (39%)
AgaP_AGAP011134	XP_309513.3	LIM1_Lhx1_Lhx5	27..78	CDD:188753
		LIM2_Lhx1_Lhx5	86..141	CDD:188761
		Homeobox	247..300	CDD:278475	20/52 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910