DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and lmx1a

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_002934210.1	Gene:	lmx1a / 100492433	XenbaseID:	XB-GENE-481569	Length:	380	Species:	Xenopus tropicalis

Alignment Length:	166	Identity:	45/166 - (27%)
Similarity:	72/166 - (43%)	Gaps:	23/166 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1708 PNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNV 1772
            |...|:......:|...| ..|.||   ..|.....| |:.|.:.:.:|:.|.:.:|.:...|..
Frog   160 PAASDSGKSEDEDDAGKF-DDSKGP---EDGKDQKRP-KRPRTILTTQQRRAFKASFEVSSKPCR 219

  Fly  1773 GTIEFLANELGLATRTITNWFHNHRMRLK-----QQVPHGPAGQDNP--IPSRE--STSATPFDP 1828
            ...|.||.|.||:.|.:..||.|.|.::|     ||.......|.||  |||.:  ::|::..:.
Frog   220 KVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQQQDQQNPSRIPSAQTHNSSSSSVEG 284

  Fly  1829 VQ--FRILLQQRLLELHKE-------RMGMSGAPIP 1855
            :.  |..|.||:||.|.:.       :.|::...:|
Frog   285 IMNVFTTLPQQQLLSLEQNIYSADPFQQGLTPPQMP 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475	16/51 (31%)
lmx1a	XP_002934210.1	LIM1_Lmx1a	35..86	CDD:188756
		LIM	94..148	CDD:351770
		Homeobox	195..249	CDD:365835	16/53 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910