DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and uncx

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001305673.1	Gene:	uncx / 100492016	XenbaseID:	XB-GENE-920201	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	498	Identity:	99/498 - (19%)
Similarity:	162/498 - (32%)	Gaps:	160/498 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1707 GPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPN 1771
            |.:||...||:...|     ..|||           ...::.|..|:..|.|.|..||....||:
Frog    79 GDSQQYKLSDSIDPD-----KESPG-----------CKRRRTRTNFTGWQLEELEKAFNESHYPD 127

  Fly  1772 VGTIEFLANELGLATRTITNWFHNHRMRLKQQV-----PHGPAGQDNPIPSRESTSATPFDPVQF 1831
            |...|.||..|.|....:..||.|.|.:.:::.     |..||...:|    .:.|..|.||.:
Frog   128 VFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHP----TTCSGEPMDPEE- 187

  Fly  1832 RILLQQRLLELHK------ERMGMSGAPIPYPPYFAAAAILGRSLAGIPGAAAAAGAAAAAAAVG 1890
              :.::.|.::.|      ::|..:...:.:.|        |......|.:.:.:|.:
Frog   188 --IARKELEKMEKKKRKQEKKMLRNQNRLQHSP--------GDMSLHTPSSDSDSGLS------- 235

  Fly  1891 ASGGDELQALNQAFKEQMSGLDLSMPTLKRERSDDYQDDLELEGGGHNLSDNESLEGQEPEDKTT 1955
                   |.|:.      |.|:.|.|.:.:.||   |.....:..|.....::...||  .|:.:
Frog   236 -------QNLDS------SSLESSHPDMGQSRS---QTQASCDQTGQAFFQSQRNTGQ--RDRVS 282

  Fly  1956 DYEKVL---HKSALAAAAAYMSNAVRSSRRKPAAPQWVNPAG-------------------AVTN 1998
            |.|..:   |.|.|.            ...:.||.|.:||..                   .:||
Frog   283 DKESPVEANHNSGLC------------PNGRGAAFQKLNPFSVESLLSDSPPKRKTGIEFPGLTN 335

  Fly  1999 PSAVVA-------AVAAAAAAAADNERIINGVCVMQASEYGRDDTDSNKPTDGGNDSDHEHAQLE 2056
            |..::.       .:....           |..|.|||.  :.::....|:.|..||.|
Frog   336 PRTLIGKGHFLLYPITQPL-----------GFIVPQASI--KSNSAQELPSPGIKDSLH------ 381

  Fly  2057 IDQRFMEPEVHIKQEEDDDEEQSGSVNLDNEDNATSEQKL---KVINEEKLRMVRVRR------- 2111
                               ...||..:|:...|  |.|.|   |..|..:...:.|.:
Frog   382 -------------------NSNSGQPSLNTSPN--SAQNLYPNKHTNSTQSTTLTVCKTENGDHH 425

  Fly  2112 --LSSTGGGSSEEMPAPLAPPPPPPAASSSIVSGESTTSSSSS 2152
              .||:|...:|::.:..:.|..|.:..|...:.|....|:|:
Frog   426 GATSSSGDTGTEQLDSTYSEPKSPKSLKSDRETPECPNGSTST 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475	19/51 (37%)
uncx	NP_001305673.1	homeobox domain	101..160		19/58 (33%)
uncx	NP_001305673.1	Homeobox	104..158	CDD:365835	19/53 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910