DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and shox

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_004911874.1	Gene:	shox / 100486480	XenbaseID:	XB-GENE-920752	Length:	334	Species:	Xenopus tropicalis

Alignment Length:	234	Identity:	55/234 - (23%)
Similarity:	80/234 - (34%)	Gaps:	47/234 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1680 LSDANNVERLQLLKNERREASK--------RRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVG 1736
            ::|.:|...|.|.|....::.|        .|.|.|..:.....|...::..|..|..
Frog    97 ITDTSNHCPLHLYKEHGADSDKDKLKDYGSTRVSEGIYECKEKRDDVKSEDEDGQTKL------- 154

  Fly  1737 SGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMRLK 1801
                   ..::.|..|:.||...|...|....||:....|.|:..|||:...:..||.|.|.:.:
Frog   155 -------KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCR 212

  Fly  1802 QQVPHGPAGQDNPIPSRESTSAT--------------PFDPVQFRILLQQRLLELHKERMGMSGA 1852
            :|......|....|....|...|              ||..||.::.| :.:...|........|
Frog   213 KQENQMHKGGYGVILGTGSHLETCRVAPYVNMGALRMPFQQVQAQLQL-EGVAHAHPHLHPHLAA 276

  Fly  1853 PIPY----PPYFAAAAILGRSLAGIPGAAAAAGAAAAAA 1887
            ..||    ||.|      |..:|.:...|:||...||||
Frog   277 HAPYLMFPPPPF------GLPIASLADTASAAAVVAAAA 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	2/9 (22%)
		Homeobox	1749..1801	CDD:278475	17/51 (33%)
shox	XP_004911874.1	Homeobox	159..213	CDD:365835	17/53 (32%)
shox	XP_004911874.1	OAR	314..330	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910