DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and pou5f3.3

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001123836.1	Gene:	pou5f3.3 / 100170593	XenbaseID:	XB-GENE-5903504	Length:	423	Species:	Xenopus tropicalis

Alignment Length:	361	Identity:	79/361 - (21%)
Similarity:	112/361 - (31%)	Gaps:	124/361 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly  1538 HHQSMLLTSP--GLPPQHAISLPPSA---GGAQPG----GPGGN--QGSSNPSNSEKKPMLMPVH 1591
            ||      :|  |.|...|:.||..|   ||.:|.    .|..:  .|:||..:.|....|
Frog   129 HH------APWQGNPTGQALGLPSRAHPDGGEKPQQSDCSPTASLESGASNTEDEEVSSAL---- 183

  Fly  1592 GTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELL 1656
            .:.|.|.|.. .||......:..::    |.||..:....|..:.||   ...||.:||.:.
Frog   184 SSRAERGLCS-PSPNNASFGSGNEE----DGTTLEEMEEFAKELKQK---RVALGYTQGDIG--- 237

  Fly  1657 SKPKPWHMLSIKGREPFIR----------------------MQLWLSDANNVERLQ-LLKNERRE 1698
                  |.|.|...:.|.:                      ::.||.:|.|.:.|| ::...:.|
Frog   238 ------HALGILYGKMFSQTTICRFESLQLTFKNMCKLKPLLEQWLGEAENNDNLQEMIHKAQLE 296

  Fly  1699 ASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLA 1763
            ...|:|                                          |.|..|....|..|...
Frog   297 EQNRKR------------------------------------------KMRTCFDSVLKGRLEGH 319

  Fly  1764 FALDPYPNVGTIEFLANELGLATRTITNWFHNHRMRLKQQ----VPHGPAGQDNPIPSRESTSAT 1824
            |..:..|....:..:|.||||....:..||.|.|.:.|.:    ..|...|..:|:||
Frog   320 FMCNQKPGARELAEIAKELGLEKDVVRVWFCNRRQKEKSKSRMSKAHEFVGGASPVPS------- 377

  Fly  1825 PFDPVQFRILLQQRLLELHKERMGMSGAPIPYPPYF 1860
               |.: .|.....|..||..|      |..|||.|
Frog   378 ---PAE-HISQDYGLAPLHPNR------PPFYPPPF 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	18/95 (19%)
		Homeobox	1749..1801	CDD:278475	15/51 (29%)
pou5f3.3	NP_001123836.1	PTZ00395	<7..>177	CDD:185594	16/53 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	85..211		24/96 (25%)
		POU	207..281	CDD:197673	16/89 (18%)
		Homeobox	305..357	CDD:365835	15/51 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910