DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and hoxa3

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001120901.1	Gene:	hoxa3 / 100151729	XenbaseID:	XB-GENE-482267	Length:	406	Species:	Xenopus tropicalis

Alignment Length:	335	Identity:	71/335 - (21%)
Similarity:	112/335 - (33%)	Gaps:	103/335 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1705 STGPNQQDNSSDTSSNDTNDFYTS---------------------SPGPGSVGSGVGG--APP-- 1744
            |..|.|..:::.|:|::.....||                     ..|..|.|....|  :||
Frog    97 SVSPPQTTSNAATASSNKATSITSPTMSKQIFPWMKESRQNTKQQKAGSSSSGESCAGDKSPPGQ 161

  Fly  1745 --SKKQRVLFSEEQKEALRLAFALDPY---PNVGTIEFLANELGLATRTITNWFHNHRMRLK--- 1801
              ||:.|..::..|...|...|..:.|   |.  .:| :||.|.|..|.|..||.|.||:.|
Frog   162 SSSKRARTAYTSAQLVELEKEFHFNRYLCRPR--RVE-MANLLNLTERQIKIWFQNRRMKYKKDQ 223

  Fly  1802 --QQVPHGPAGQD---NPIPS----------RESTSATPFDPVQFRILLQQRLLELHKERMGMSG 1851
              :.:.....||.   :|:|:          ....::.|::|        |.....:|......|
Frog   224 KGKSMMTSSGGQSPCRSPVPTPSVGGYLNSMHSLVNSVPYEP--------QSPPAFNKHHPSAYG 280

  Fly  1852 APIPYP-PYFAAAAILGRSLAGIPGAAAAAGAAAAA---------AAVGASGGDELQA----LNQ 1902
            .|.||| |:.:..          |.....:|.||..         .:.||.|...:|.    :..
Frog   281 VPAPYPSPHNSCP----------PHQKRYSGTAAVTPEYEPHPLQQSSGAYGNPHVQGSPVYVGG 335

  Fly  1903 AFKEQMSGLDLSM---PTLKRERSD-DYQDDLELEGGGH-----------NLSDNESLEGQEPED 1952
            .:.|.|:....||   ..|....|: ||.....:..|.|           :||.:.:     |:.
Frog   336 NYVETMTNSGPSMFGLSHLSHSSSNMDYSGAGPMNSGHHHGPCDSHPTYTDLSAHHN-----PQG 395

  Fly  1953 KTTDYEKVLH 1962
            :..:..|:.|
Frog   396 RIQEAPKLTH 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475	18/54 (33%)
hoxa3	NP_001120901.1	Homeobox	168..221	CDD:395001	18/55 (33%)
hoxa3	NP_001120901.1	DUF4074	344..404	CDD:404218	12/64 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910