DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and shox2

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001093694.1	Gene:	shox2 / 100101703	XenbaseID:	XB-GENE-480993	Length:	311	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	54/272 - (19%)
Similarity:	88/272 - (32%)	Gaps:	79/272 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1670 REPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGS 1734
            |.|.:.:.|      :|||:      |...|.:.....|..::...:.......:     .|...
Frog    70 RSPVLELDL------SVERI------RESGSPKLTEVSPEIKERKEELKQQALEE-----EGQTK 117

  Fly  1735 VGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMR 1799
            :        ..::.|..|:.||...|...|....||:....|.|:..|||:...:..||.|.|.:
Frog   118 I--------KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAK 174

  Fly  1800 LKQQ---------------------VPHGPAG-------QDN--PIPSRESTSATPFDPVQFRIL 1834
            .::|                     .|:...|       ||:  .:||...       .||.::.
Frog   175 CRKQENQLHKGVLIGAGSQFEACRVAPYVNVGALRMPFQQDSHCNVPSLSF-------QVQAQLQ 232

  Fly  1835 LQQRLLELHKERMGMSGAPIPY-----PPYFAAAAILGRSLAGIPGAAAAAGAAAAAAAVGASGG 1894
            |...:...|........|..||     ||:            |:|.|..||..|.||:.|.|:..
Frog   233 LDSAVAHAHHHLHPHLTAHAPYMMFPAPPF------------GLPLATLAAETATAASVVAAAAA 285

  Fly  1895 DELQALNQAFKE 1906
            .:..:.|.:..:
Frog   286 AKTSSKNSSIAD 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	6/19 (32%)
		Homeobox	1749..1801	CDD:278475	17/51 (33%)
shox2	NP_001093694.1	Homeobox	123..177	CDD:365835	17/53 (32%)
shox2	NP_001093694.1	OAR	292..307	CDD:367680	1/6 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910