Protein Alignment rg and AT1G58230

DIOPT Version :10

• Sequence 1: NP_001284879.1
• Gene: rg / 44531
• FlyBaseID: FBgn0266098
• Length: 3785
• Species: Drosophila melanogaster
• Sequence 2: NP_564728.3
• Gene: AT1G58230 / 842191
• AraportID: AT1G58230
• Length: 2604
• Species: Arabidopsis thaliana
• Alignment Length: 3871
• Identity: 723/3871 - (18%)
• Similarity: 1183/3871 - (30%)
• Gaps: 1713/3871 - (44%)

  Fly    44 REVVNTVLHLLVGGEFDMELNFVIQDAQNIKHMLELLDHCPPNLQAEIWSVFIAILRKSVRNLQA 108
            :.:::.:|.:||.|:||.:.:.:|::...|...|.:|.....:||....::|..:||.|:.|..:
plant   304 QRLLDALLDMLVDGKFDDKGSALIKNEDVIILYLNVLQKSSESLQCYGLNLFQQLLRDSISNRAS 368

  Fly   109 CTDVGLIEHVLV---RLQRSETVVADLLIEMLGVLASYSITVKELKLLFGTMKATN-GKWPRHSA 169
            |...|:: |:|:   .|:..::|:.. :.::...:..:||:.|:::.:|..:::.. |...|:.:
plant   369 CVRAGML-HLLLDWFSLENDDSVILK-ITQLTQTIGGHSISGKDIRKIFALLRSERVGNQQRYRS 431

  Fly   170 KLLNVLRQMPHRNGPDVFFSFPGRKGSAMVLPPLAKWPYENGFTFTTWFRLDPINSVNIEREKPY 234
            .||..|..|.:..||..||...|.:...::..|: :||...||:|..|.|::......    |..
plant   432 LLLACLLSMLNEKGPTGFFDMNGVESGIVIRTPV-QWPANKGFSFCCWLRVESFPGDG----KMG 491

  Fly   235 LYCFKTSKGVGYTAHFVGNCLVLTSMKVKGKGFQHCVKY--EFQPRKWYMIAIVYIYNR--WTKS 295
            ::.|.:..|.|..|....:.|...|:.:|    :.||..  ....:||:.|.:.:...|  |..|
plant   492 IFSFMSKNGKGCFAALGKDGLSYVSLNLK----RQCVNVHTNLVCKKWHFICVSHSIGRAFWGGS 552

  Fly   296 EIKCLVNGQLASSTEMAWFVSTNDPFDKCYIG---ATPELDE----ERV-----FCGQMSAIYLF 348
            .::|.|||.|.|| |...:....|....|.||   ..|.:.:    |.:     |.||:..:|||
plant   553 LLRCYVNGDLVSS-ERCSYPKVTDVLTSCLIGTRITLPHIQDNDGLESIRDVFPFFGQIGPVYLF 616

  Fly   349 SEALTTQQICAMHRLGPGYKSQFRFDNECYLNLPDNHKRVSHFQLLPATLGASALSGGSGSGTGS 413
            :::|:::|:.|::.|||.|...| .:||......||          |...|  .|.|..|..:..
plant   617 NDSLSSEQVQAIYSLGPSYMYAF-LENEMTCPFSDN----------PFPSG--ILDGKDGLASKV 668

  Fly   414 GTGNDASAAAAAAVAAGQQQQLQLQFQILAAEQEARAIDWSDEKLDLNAAFVKIRAVLTARNAVT 478
            ..|.:|.|:....:           |.:      :|..|...|:|...|
plant   669 SFGLNAQASDGRRL-----------FNV------SRVSDHLQERLAFEA---------------- 700

  Fly   479 LAGSSSTGTTAVATAAAAAAAAGAGAGTTAAATSAAAAAAATQNENDAAVGQQQHATHHHATAAT 543
                                                                             
plant   701 ----------------------------------------------------------------- 700

  Fly   544 GSADDPLGHLPTGNASSSSSSFEQLRRMSSVSSLNSMVGSADTEEVNQLKAVLYDGKLSNAIVFM 608
                                              :.|||:
plant   701 ----------------------------------DIMVGT------------------------- 706

  Fly   609 YNPVATDGQLCLQSSPKGNVSYFVHTPHALMLQDVKAVVTHSIHCTLNSIGGIQVLFPLFSQLDM 673
                    |||.:.                :||.:       |:|    :|||.|.|||.:|.|.
plant   707 --------QLCSRR----------------LLQQI-------IYC----VGGISVFFPLITQSDR 736

  Fly   674 A-----HEGLGDIKRDPTLCSKLLGFICELVETSQTVQQHMIQNRGFLVISFMLQRSSREHLTLE 733
            .     :|....:.....:.::::..|..:::.:...||.|....||.::.|:||....:.|.||
plant   737 CESETLNEETSAMPTKERMTAEVIELIASVLDENPANQQQMHLLAGFPILGFLLQSIQPKQLNLE 801

  Fly   734 VLGSFLNLTKYLVTCLSANSDLLLKQLFCFSFLTWQLLDHVLFNPALWIYTPANVQARLYSYLAT 798
            .|.|.    |:|...:|::.  ..:|      |....:..:..||.:|::...|||..||.:|..
plant   802 TLSSL----KHLFNVISSSG--FAEQ------LVEDAISSIFLNPHIWLHAAYNVQRELYMFLIQ 854

  Fly   799 EFLSDTQIYSNVRRVSTVLQTVHTLKYYYWVVNPRAKSG---IIPKGLDGPRPAQKDILAIRAYI 860
            :..:|.::..::.|:..|:..|..   :||......|..   :.|......||::.:|..|| .:
plant   855 QLDNDPRLLGSLCRLPRVIDIVWN---FYWESERYCKGSKPLMHPTRTIAERPSRDEIHKIR-LL 915

  Fly   861 LLFLKQLIMIGNGVKEDELQSILNYLTTMHEDENLHDVLQMLISLMSEHPSSMVPAF----DVKH 921
            ||.|.::.:..| :...:::::..:..|..:...:.|||.|:|..:|:  :|::.:|    ::..
plant   916 LLSLGEMSLRHN-ISSGDVKALTAFFETCQDVACIEDVLHMVIRAISQ--TSVLVSFLEQVNLIG 977

  Fly   922 GVRSIFKLLAAESQLIRLQALKLLGFFLSRSTHKRKYDVMSPHN--------------------- 965
            |......||..:.:.|||.:|:.||..|        |||.|...
plant   978 GCHIFVDLLQRDYEPIRLLSLQFLGRLL--------YDVPSERKGPKFFNLAVGRTKSLSQGHKK 1034

  Fly   966 -------LYTLLAERLLLY--EESLSLPTYNVLY------EIMTEHISQQILYTRHPEPESHYRL 1015
                   ::..:::||..|  .::|....::||.      :::.:|  .|:...|.....||:.|
plant  1035 IGARTQPIFLAMSDRLFQYPQTDNLRATLFDVLLGGASPKQVLQKH--NQVDKHRSKPSNSHFFL 1097

  Fly  1016 ENPMILKVVATLIRQSKQTESLIDVKKLFLQDMTLLCNSNRENRRTVLQMSVWQEWLIA---MAY 1077
              |.|...:...:...|  :.|..:|  .:.|:..|.:||..|...:::.. |..||.|   :..
plant  1098 --PQIFVFIFEFLSGCK--DGLARMK--IISDILDLLDSNPMNVEALMEFG-WSAWLTASMKLDV 1155

  Fly  1078 IHPKSSEEQKISDM-------VYSLFRMLLHHAIKHEYGGWRVWVDTLAIV-----HSKVSYEEF 1130
            |....||.....|:       |..||.::|.|.|....|||:...:|:..:     |:.|.|..|
plant  1156 IKDYRSELLNHDDLALNEQHFVRGLFCVVLCHYILSVKGGWQQLEETVNFILLQSEHNDVPYRSF 1220

  Fly  1131 KLQFAQMYEHYERQRTDNITDPALRQARPISTISGWEREELHQQQNGGSAAAVATNQTAAVKGSV 1195
               ...:||.                                                 .::..|
plant  1221 ---LRDLYED-------------------------------------------------LIQRLV 1233

  Fly  1196 SIASLEDVPPVVEEEVEELELEEVEIQEGPITEETEQKSVIANISDVYNEQLKTDATCNGNLEDV 1260
            .::|.:::  .:.....:..|..:.:.:..:..|...:.:...||..::|.|
plant  1234 ELSSEDNI--FLSHPCRDNVLYLLRLVDEMLVREFGSRLLFPAISTDFSEDL------------- 1283

  Fly  1261 KEEEPVQQQIGDLEKQPEPSTPLGALRETLQLGDDMDVEELELATAKDALNAEQHVSRVLQASEA 1325
                                         ||||:..|          ..|..::...|.|....:
plant  1284 -----------------------------LQLGNRED----------PTLGLDESFQRFLTEEIS 1309

  Fly  1326 ALNDCKMAVDDVLQESSSVLKDEEIELAVNEVVQGVLNNEKKTQSQDNKDNKEQPGEQDVNVSLL 1390
            ...:|:.:...|.:                     ::.||:.....|
plant  1310 RNTECQQSCTTVTE---------------------LMTNERWWNLYD------------------ 1335

  Fly  1391 NSKNLLNNNNNNNNNSPSPTPTTATATAETEAETEVNANEIVSSTEAPKAETETSVAPEVETPET 1455
               ||.....:.|...|......:.||..:..:   .|..:|.|...|.||.
plant  1336 ---NLWKIICDINGRGPVKMSPKSLATGPSIGQ---RARGLVESLNVPAAEM------------- 1381

  Fly  1456 AKPSPIVPSPVLATNQKTEDAANKLNNNEKLAEISASPEPPIVVETPEADLLQLSDSETKPNKET 1520
                    :.|:.:.......:.|:|.|
plant  1382 --------AAVVVSGGIGSALSGKMNKN------------------------------------- 1401

  Fly  1521 EAEDSVALAVRDIVEQLIDKVIDATEAESASETKTETNNNEIPKKEKQTSEEPEDVETAETLAAA 1585
                             :||.:                   :.:.||
plant  1402 -----------------VDKAM-------------------LLRGEK------------------ 1412

  Fly  1586 AKEIVQEVVEAALVMVQEESTQEKPEKGANSEEEKNEIGKEEILLQLEEKPASTEVQETKIEGDL 1650
            ...||..:|...|.|
plant  1413 CPRIVFRLVTLYLCM-------------------------------------------------- 1427

  Fly  1651 KKPEDPKGHSSVEPKTPNLEEPKPQETEQQKSQEVAEELPQKPEEQVVAIVNQVLDTLVDDTVKA 1715
                     ||:|..|                                ..|.||...|
plant  1428 ---------SSLEKAT--------------------------------RCVQQVTSLL------- 1444

  Fly  1716 VAAEQTTQTSPAPEEQSPQILAMESPATSVRVKPTEVDSTTQTTPKNEAGSSLLVEQVQQVLQED 1780
                             |..||                                         .|
plant  1445 -----------------PSFLA-----------------------------------------AD 1451

  Fly  1781 DAQQSAGMTIEDEDYSNQQAAAAVENANSSQLDANHYGPGNPESKQQQQRSKSGSTRPMFSPGPT 1845
            |.|                                               |||
plant  1452 DEQ-----------------------------------------------SKS------------ 1457

  Fly  1846 RPPFRIPEFKWSYIHQRLLSDVLFSLETDIQVWRSHSTKSVLDFVNSSENAIFVVNTVHLISQLA 1910
                                             |.|.....|.:|.|....:......|:||.|.
plant  1458 ---------------------------------RLHLFIGCLLYVRSQYGKLDDGARFHVISHLI 1489

  Fly  1911 DNLIIACGGLLPLLASATSPNSELDVLEPTQGMPLEVAVSFLQRLVNMADVLIFATSLNFGELEA 1975
            .. .::||  ..:||              |.||                              ..
plant  1490 RE-TVSCG--KSILA--------------TSGM------------------------------NK 1507

  Fly  1976 EKNMSSGGILRQCLRLVCTCAVRNCLECKERTRYNVGALARDVPGAAHLQALIRGAQASPKNIVE 2040
            :.:..||||.::      ..:::|.:. |:|                               ::.
plant  1508 DDSSDSGGIFKE------MGSIQNLIH-KDR-------------------------------VLA 1534

  Fly  2041 SITGQLSPVKDPEKLLQDMDVNRLRAVIYRDVEETKQAQFLSLAIVYFISVLMVSKYRDILEPPA 2105
            ::|.:.:.:|   .|:.|               .|:|.|.|.......:|:...||
plant  1535 AVTDETTYMK---TLISD---------------RTRQVQALGERNNETLSIECNSK--------- 1572

  Fly  2106 EPQIQRQSPVLQRTAGGEAASARPLFPQWSHHVYPQFLPESHQNHNSNMQHQQQQQQQQQHQQQQ 2170
                        :...||..:.......|.            :|...::|...::|||...::..
plant  1573 ------------KAFDGELQNVLKTVVTWD------------ENRRVSVQLSHEEQQQNVTEKWI 1613

  Fly  2171 HYYQQQQQQQVVHNHSHHHMTAAYYQQQQHQQVAAGQQQHSPTPLATHSTSSSASSTATSQPASS 2235
            |..:....::                         |....:|.|
plant  1614 HMLRSLMDER-------------------------GPWSATPFP--------------------- 1632

  Fly  2236 SSLSSLASQSQQQSHRQLHKQQQQQQQQQQQQQPHYHPHQPHYGLINGHQQHPQLNGKHYAENGS 2300
                          :..|::.:..:.:...:::|
plant  1633 --------------NNILNRWKLDRTEDSWRRRP------------------------------- 1652

  Fly  2301 TAGYHPHSHPHPHGGYMRNGDTSTLQQNGMPDYQAVGLMNGHGSGGTGNNNNSSLMNNMRNLRNG 2365
                                                                             
plant  1653 ----------------------------------------------------------------- 1652

  Fly  2366 GGANSSSSPPGSHQVIQGVATAGAVNANAAVGVGMGGAVGVGMGGVAGGLDGGVVYKTSAINNNY 2430
                                                                       .:..||
plant  1653 -----------------------------------------------------------KLRRNY 1658

  Fly  2431 RYNGRNASAGTGGRQIQDSDYEIIVVDENNPSVLADNDSHSSGPPSIKANQTTTIATTTTTTATT 2495
            .:                                   |.....|||             |:|||
plant  1659 HF-----------------------------------DERLCHPPS-------------TSTAT- 1674

  Fly  2496 HINNNNTKTTTSNAPTATIKIQQQPLSPPKPLVPQKLPKSVDSDVGSLNMNSTENEVPEVESSSE 2560
               .|.|....:.:.:..|.|.:|        :.:.|.|.:.........:|.||:..:.|.|
plant  1675 ---ENETSNVINESKSGVIHIPEQ--------MKKFLLKGIRRITDEGGSDSCENDSSQAEQS-- 1726

  Fly  2561 ILIDDHKPSHSNDESWTDVNLNEDAAVQAASAGIVVGLVDNRGNVISDKHDPSHHNQQQQQQAGI 2625
             .:|            |..::.....|:.:|     ||.|    |:.||.|.|..
plant  1727 -FMD------------TSADIQFSELVRTSS-----GLKD----VVQDKVDASSL---------- 1759

  Fly  2626 IGQQQQHGSLGHSERGDKPDSEISVVRVPDGYGGAGSGGGVNSGQGQGVPSNQRPRPEELPMKAP 2690
                    .:|.||
plant  1760 --------EVGTSE--------------------------------------------------- 1765

  Fly  2691 ALVAQLP--LTTPSREASLTQKLEIALGPVCPLLREIMVDFAPFLS--KTLVGSHGQELLMEGK- 2750
             ::..:|  |.||.|:                        .|.:|:  |.::...| |.|:||.
plant  1766 -VLTSVPCVLVTPKRK------------------------LAGWLAVMKNVLHFSG-EFLVEGTG 1804

  Fly  2751 GLTTFKNSHSVVELVMLLCSQEWQNSLQKHAGLAFIELINEGRLLSHAMKDHIVRVANEAEFILN 2815
            |...|||                                                        .:
plant  1805 GSAVFKN--------------------------------------------------------FS 1813

  Fly  2816 RMRADDVLKHADFESQCAQTLLERREEERMCDHLITAARRRDNVIASRLLEKVRNIMCNRHGAWG 2880
            ..:..||                            |.|..:.|::                 .|
plant  1814 TSKGSDV----------------------------TKAENKQNLV-----------------KW- 1832

  Fly  2881 DSSSTSSGGAIVGAVQKSPYWKLDAWEDDARRRKRMVQNPRGSSHPQATLKAALENGGPEDAILQ 2945
                            .|||
plant  1833 ----------------SSPY--------------------------------------------- 1836

  Fly  2946 TRDEFHTQIAVSRTHPSGQHNGELLDDAELLIEDRELDLDLTGPVNISTKARLIAPGLVAPGTVS 3010
                                             |.|..|||...
plant  1837 ---------------------------------DSETFLDLESG--------------------- 1847

  Fly  3011 ITSTEMFFEVDEEHPEFQKIDGEVLKYCDHLHGKWYFSEVRAIFSRRYLLQNVALEIFLASRTSI 3075
                      ::.....:|:         ..|.:|...:|:::...|||||..|||||.......
plant  1848 ----------NKNKKPLKKV---------KRHRRWKIGKVKSVHWTRYLLQYTALEIFFQESVPP 1893

  Fly  3076 LFA-FPDQHTVKKVIKAL---------PRVGVGIKYGIPQTRRA--SMMSPRQLMRNSNMTQ-KW 3127
            :|. |..|...|:|...:         |:       .:|:.|.|  |.:..|..|..:...: :|
plant  1894 VFLNFASQKNAKEVGMLIVSTRNEFLFPK-------NVPRDRTAMISFVDRRIAMEMAETARDRW 1951

  Fly  3128 QRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSR 3192
            :||||:||||||.|||:|||:||||.|||:||||:.:|.|:.||.|..|.:||||||:|||:..|
plant  1952 RRREITNFEYLMILNTLAGRSYNDLTQYPVFPWVVADYSSETLDFSKASTFRDLSKPVGALDTRR 2016

  Fly  3193 RAYFEERYESWDSDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSL 3257
            ...||:||.|:....||.|:||:|||:....|.:|:|:||||::..:|||||||:.||||.||..
plant  2017 FEIFEDRYHSFSDPDIPSFYYGSHYSSMGSVLYYLLRLEPFTSLHRSLQGGKFDHADRLFQSVEG 2081

  Fly  3258 SWKNCQRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAK-SPEEFVRINRM 3321
            |::||..:||||||||||::::||...||:.|.||.::||..:.::.|||||| |||.|:..||.
plant  2082 SFRNCLSNTSDVKELIPEFFYMPEFLVNSNSYHLGVKQDGEPLGEVCLPPWAKGSPEMFIARNRE 2146

  Fly  3322 ALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNF 3386
            |||||:||..||.|||||||:||||..|:.|.|:||||||||:||::.:.|.:...|:|:||.||
plant  2147 ALESEYVSSHLHDWIDLIFGHKQRGKPAVEAANIFYYLTYEGAVDVENMEDQLQISAIEDQIANF 2211

  Fly  3387 GQTPSQLLMEPHPPRSSAMHLS-PMMFSAMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTV 3450
            ||||.|:..:.||.|...:.:: |:.|:....:|..:|....:||    ||..|..:...::|.|
plant  2212 GQTPIQIFRKKHPRRGPPIPIAHPLYFAPASINLSSILPATTHSP----SAVLYVGVVDSNIVLV 2272

  Fly  3451 TAGHQFAVNRW-------NCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRR 3508
            ..|...:|..|       ..|:|.|        |.|          ||...|     .|:..|.|
plant  2273 NQGLTLSVKIWLTTQLHSGGNFTFS--------SAQ----------DPFFGV-----GSDVLSPR 2314

  Fly  3509 HLGDNFSQMLKIRSNCFVTTVD--SRFLIACGFWDNSFRVFATETAKIVQIVFGHFGVVTCMARS 3571
            ::|...:..:::.|.||.....  ..||::||.|:|||.|.:....::||.:..|..||:|:|
plant  2315 NIGSPLADNVELGSQCFAAMQMPLENFLVSCGNWENSFHVISLTDGRVVQSIRHHKDVVSCVA-- 2377

  Fly  3572 ECNITSDCYI-ASGSADCTVLLW---------------HWNARTQSIVGEGDVPTPRATLTGHEQ 3620
               :|:|..| |:||.|.||::|               |.....:.||   ....|...|.||:.
plant  2378 ---VTADSTILATGSYDTTVMVWDILRMRTPEKRVRNTHAEVLRKDIV---IADAPSHILCGHDD 2436

  Fly  3621 AVTSVVISAELGLVVSGSSNGPVLIHT-TFGDLLRSLDPPAEFHSPELITMSREGFIVINYDKG- 3683
            .:|.:.:|.:|.:|:|||.:|..:.|| ..|..:|||..|:. .:...:..|..|.||:..|..
plant  2437 IITCLYVSTDLDIVISGSKDGTCVFHTLREGRYIRSLKHPSG-SAVSKLAASHHGRIVLYGDDDL 2500

  Fly  3684 NVAAYTINGKKLRHETHNDNLQCMLLSRDGEYLMTAGDRG--IVEVWRTFNLAPLYAFPACNAG- 3745
            ::..|:||||.|.....|..:.|:.||:.||:|::|||:|  ||....|..:...|.    .||
plant  2501 SLHLYSINGKHLASSESNGRINCLELSKCGEFLVSAGDQGQIIVRSMNTLEVVKRYN----GAGK 2561

  Fly  3746 -IRSLALTHDQKYLLAGLSTGSIIVFHIDFNRWHHE 3780
             |.||.:|.::.: |||...|:::|:.|: |..|.:
plant  2562 IITSLTVTQEECF-LAGTKDGALLVYSIE-NPQHRK 2595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rg	NP_001284879.1	Laminin_G_3	210..358	CDD:463865	43/163 (26%)
		DUF4704	629..1123	CDD:464870	122/556 (22%)
		PspC_subgroup_2	<1433..1807	CDD:468202	31/373 (8%)
		DUF1088	2791..2972	CDD:461925	9/180 (5%)
		PH_BEACH	2996..3093	CDD:434260	19/106 (18%)
		Beach	3125..3401	CDD:460459	158/277 (57%)
		NBCH_WD40	3502..3774	CDD:466575	93/295 (32%)
		WD40 repeat	3524..3560	CDD:293791	13/37 (35%)
		WD40 repeat	3566..3617	CDD:293791	17/66 (26%)
		WD40 repeat	3622..3657	CDD:293791	13/35 (37%)
		WD40 repeat	3669..3699	CDD:293791	11/30 (37%)
		WD40 repeat	3704..3739	CDD:293791	14/36 (39%)
AT1G58230	NP_564728.3	Neurobeachin	19..431	CDD:466574	29/128 (23%)
		Laminin_G_3	469..626	CDD:463865	43/165 (26%)
		DUF4704	698..1208	CDD:464870	129/720 (18%)
		DUF4800	<1590..1661	CDD:464996	13/332 (4%)
		PH-like	1766..1915	CDD:473070	50/409 (12%)
		Beach	1949..2226	CDD:460459	158/276 (57%)
		NBCH_WD40	2247..2596	CDD:466575	114/391 (29%)
		WD40 repeat	2374..2411	CDD:293791	12/41 (29%)
		WD40 repeat	2439..2474	CDD:293791	13/34 (38%)
		WD40 repeat	2481..2514	CDD:293791	11/32 (34%)
		WD40 repeat	2521..2557	CDD:293791	13/35 (37%)
		WD40 repeat	2563..2586	CDD:293791	8/23 (35%)