|
Fly 28 KFAVLIGLIEVGQVTNREVVNTVLHLLVGGEFDMELNFVIQDAQNIKHMLELLDHCPPNLQAEIW 92
|||||||||:||:|:||::|.|||:||||||||:|:||:||||:.|..|||||:||....|||||
Zfish 65 KFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAEAIICMLELLEHCEVTCQAEIW 129
Fly 93 SVFIAILRKSVRNLQACTDVGLIEHVLVRLQRSETVVADLLIEMLGVLASYSITVKELKLLFGTM 157
|:|.|||||||||||..::||||:.:|:::...:.::||||::|||||||||||||||||||..:
Zfish 130 SMFTAILRKSVRNLQTSSEVGLIQRLLIKMSSVDDMIADLLVDMLGVLASYSITVKELKLLFSML 194
Fly 158 KATNGKWPRHSAKLLNVLRQMPHRNGPDVFFSFPGRKGSAMVLPPLAKWPYENGFTFTTWFRLDP 222
:...|.||||:.|||:||.||..|:|||.||:||||..:|:.|||:|||||:||||..||||:||
Zfish 195 RGEGGLWPRHAVKLLSVLSQMAQRHGPDTFFNFPGRSAAAIALPPIAKWPYQNGFTLNTWFRMDP 259
Fly 223 INSVNIEREKPYLYCFKTSKGVGYTAHFVGNCLVLTSMKVKGKGFQHCVKYEFQPRKWYMIAIVY 287
:|::|::::|||||||:||||:||:||||||||::||:|.|||||||||||:||||||||::||:
Zfish 260 LNNINVDKDKPYLYCFRTSKGIGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMVSIVH 324
Fly 288 IYNRWTKSEIKCLVNGQLASSTEMAWFVSTNDPFDKCYIGATPELDEERVFCGQMSAIYLFSEAL 352
|||||..|||:|.|||||.|..:|||.|:|||.:|||::|::...|..||||||:.|||:|||||
Zfish 325 IYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAIYVFSEAL 389
Fly 353 TTQQICAMHRLGPGYKSQFRFDNECYLNLPDNHKRVSHFQLLPATLGASALSGGSGSGTGSGTGN 417
...||.|:|:|||||||.|:|.:|..::|.|:||:
Zfish 390 NPAQIFAIHQLGPGYKSTFKFKSESDIHLADHHKQ------------------------------ 424
Fly 418 DASAAAAAAVAAGQQQQLQLQFQILAAEQEARAIDWSDEKLDLNAAFVKIRAVLTARNAVTLAGS 482
Zfish 425 ----------------------------------------------------------------- 424
Fly 483 SSTGTTAVATAAAAAAAAGAGAGTTAAATSAAAAAAATQNENDAAVGQQQHATHHHATAATGSAD 547
Zfish 425 ----------------------------------------------------------------- 424
Fly 548 DPLGHLPTGNASSSSSSFEQLRRMSSVSSLNSMVGSADTEEVNQLKAVLYDGKLSNAIVFMYNPV 612
|||||||:|:|.|.||..
Zfish 425 -----------------------------------------------VLYDGKLANSISFTYNAK 442
Fly 613 ATDGQLCLQSSPKGNVSYFVHTPHALMLQDVKAVVTHSIHCTLNSIGGIQVLFPLFSQLDMAHEG 677
|||.||||:|||:.|.|.|||:|||||||||||:||||||..::||||||||||||:|||.....
Zfish 443 ATDAQLCLESSPRENPSIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDFHQHN 507
Fly 678 LGDIKRDPTLCSKLLGFICELVETSQTVQQHMIQNRGFLVISFMLQRSSREHLTLEVLGSFLNLT 742
...: :.|:||.||.|:.||:::|..:|:.|:..:|||||.::|::|||.|:|..||..||:..
Zfish 508 ESQV--ETTVCSTLLAFLMELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHVTRAVLDQFLSFA 570
Fly 743 KYLVTCLSANSDLLLKQLFCFSFLTWQLLDHVLFNPALWIYTPANVQARLYSYLATEFLSDTQIY 807
||| ..|:..:.||. ||.||:|||.|:||:.||.||..||:||::||:..|.||
Zfish 571 KYL-DGLTHGAPLLK-----------QLCDHILFNAAIWIHIPAKVQLSLYTYLSSEFIGTTTIY 623
Fly 808 SNVRRVSTVLQTVHTLKYYYWVVNPRAKSGIIPKGLDGPRPAQKDILAIRAYILLFLKQLIMIGN 872
|.:|||.||||.:|.||||||.|||...|||.|||||||||:||:|.::||::||||||||:...
Zfish 624 STIRRVGTVLQIMHILKYYYWAVNPNNTSGITPKGLDGPRPSQKEISSLRAFMLLFLKQLILKDR 688
Fly 873 GVKEDELQSILNYLTTMHEDENLHDVLQMLISLMSEHPSSMVPAFDVKHGVRSIFKLLAAESQLI 937
||||||||||||||.|||||||||||||:|::||||||:||:||||.::|:|.::||||::|:.|
Zfish 689 GVKEDELQSILNYLLTMHEDENLHDVLQLLVALMSEHPASMIPAFDQRNGIRVVYKLLASKSESI 753
Fly 938 RLQALKLLGFFLSRSTHKRKYDVMSPHNLYTLLAERLLLYEESLSLPTYNVLYEIMTEHISQQIL 1002
|:||||:|.:||....||||.::|..::|:|||.|||:|:..::|:.|||.||||:||.:..|::
Zfish 754 RVQALKVLAYFLKHLGHKRKVEIMHTNSLFTLLGERLMLHSNTVSITTYNTLYEILTEQVCTQVV 818
Fly 1003 YTRHPEPESHYRLENPMILKVVATLIRQSKQTESLIDVKKLFLQDMTLLCNSNRENRRTVLQMSV 1067
:..|.||:|..:::|||||||||||::.|..:..|::|::|||.||..|.:::|||||.:||.||
Zfish 819 HKPHVEPDSTVKIQNPMILKVVATLLKNSTPSADLMEVRRLFLSDMIKLFSNSRENRRCLLQCSV 883
Fly 1068 WQEWLIAMAYIHPKSSEEQKISDMVYSLFRMLLHHAIKHEYGGWRVWVDTLAIVHSKVSYEEFKL 1132
||:|:.::.||:||:||||||::|||::||:||:||||||:||||||||||:|.||||:||..|.
Zfish 884 WQDWMFSLGYINPKNSEEQKITEMVYNIFRILLYHAIKHEWGGWRVWVDTLSIAHSKVTYEAHKE 948
Fly 1133 QFAQMYEHYERQRTDNITDPALRQARP--ISTISGWEREELHQQQNGGSAAAVATNQTAAVKGSV 1195
..|:|||.|:||..:|| ::.:. :||||| .:.|.:::||::
Zfish 949 YLAKMYEEYQRQEEENI-----KKGKKGLVSTISG------------------LSAQASSIKGTL 990
Fly 1196 SI-ASLEDVPPVVEEEVEELELEE----VEIQEGPITEETEQKSVIANISDVYNEQLKTDATCNG 1255
.: |..:...| |.|.:|.|..: :..:...:.|:.....|...:.|:
Zfish 991 ELDADSQTQTP--ESEADEPETTDSGRNILSETKSLDEDNPASGVHVEVHDL------------- 1040
Fly 1256 NLEDVKEE--EPVQQQIGDLEKQPEPSTPLGALRETLQLGDDMDVEELELATAKDALNAEQHVSR 1318
|.|:|.| |..:.::.||:.. |.|..|.|.|...|.|:: .:.|.:.||:
Zfish 1041 -LVDIKAEKVEATEVKMDDLDLL--PVTENGGLVEVDSLLDNV------YSAAVEKLNS------ 1090
Fly 1319 VLQASEAALNDCKMAVDDVLQESSSVLKDEEIELAVNEVVQGVLNNEKKTQSQDNKDNKEQPGEQ 1383
:|::||...:|: :||::...
Zfish 1091 --------------SVNNVLVPKASL---------------------------ENKNSGPL---- 1110
Fly 1384 DVNVSLLNSKNLLNNNNNNNNNSPSPTPTTATATAETEAETEVNANEIVSSTEAPKAETETSVAP 1448
::|.:.|:.:::||. ....|.|:.:.| ::.|
Zfish 1111 ---ITLADEKDAISSNNT------FLFGTLASGSGE-------------------------NLLP 1141
Fly 1449 EVETPETAKPSPIVPSPVLATNQKTEDAANKLNNNEKLAEISASPEPPIVVETPEADLLQLSDSE 1513
|: .|..|.|: |...|.|..:..|||..|: ..
Zfish 1142 EI--------GPSEPLPL-------------------------SGVEPQVHTSSSADLGLLA-LM 1172
Fly 1514 TKPNKETEAEDSVALAVRDIVEQLIDKVIDATEAESASETKTETNNNEIPKKEKQTSEEPEDVET 1578
:|.:||..| ::||| |....|:..|....|.||.::.| :.|..|||
Zfish 1173 SKSSKELSA-NTVAL------EDDSFKMQPALSGFSISEGESLT-------------KCPGQVET 1217
Fly 1579 A----ETLAAAAKEIVQEVVEAALVMVQEESTQEKPEKGANSEEEKNEIGKEEILLQLEEKPAST 1639
. |..|:..|:: :.|:.||::.|||:
Zfish 1218 VAVDLEQGASGVKDV------------------------STSDTEKSDDGKEK------------ 1246
Fly 1640 EVQETKIEGDLKKPEDPKGHSSVEPKTPNLEEPKPQETEQQKSQEVAEELPQKPEEQVVAIVNQV 1704
Zfish 1247 ----------------------------------------------------------------- 1246
Fly 1705 LDTLVDDTVKAVAAEQTTQTSPAPEEQSPQILAMESPATSVRVKPTEVDSTTQTTPKNEAGSSLL 1769
.:|..:..:|||:. ...:||.|
Zfish 1247 -----------------------------------------EIKKIQTTATTQSL-HGRSGSHL- 1268
Fly 1770 VEQVQQVLQEDDAQQSAGMTIEDEDYSNQQAAAAVENANSSQLDANHYGPGNPESKQQQQRSKSG 1834
|.|........|: |.:::|
Zfish 1269 ----------------------DRDLRVDLGFRAM-----------------PMTEEQ------- 1287
Fly 1835 STRPMFSPGPTRPPFRIPEFKWSYIHQRLLSDVLFSLETDIQVWRSHSTKSVLDFVNSSENAIFV 1899
|..|||||....|||||||||.:|||||:|:||:||:|:.:||||||||::|||||:||.|||
Zfish 1288 --RRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALESDVHIWRSHSTKSIMDFVNSNENIIFV 1350
Fly 1900 VNTVHLISQLADNLIIACGGLLPLLASATSPNSELDVLEPTQGMPLEVAVSFLQRLVNMADVLIF 1964
.||:|||||:.||:||||||:||||::||||:||::.||.||||..|.||.||.||:.:.|||:|
Zfish 1351 HNTIHLISQMVDNIIIACGGILPLLSAATSPSSEMEGLEVTQGMSSETAVIFLTRLMAIVDVLVF 1415
Fly 1965 ATSLNFGELEAEKNMSSGGILRQCLRLVCTCAVRNCLECKERTRYNVGALARDVPGAAHLQALIR 2029
|:||||.|:||||||||||::||||||||..||||||||::|.| .|.:..:........
Zfish 1416 ASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQR------DRSLKSSLSCSKSQE 1474
Fly 2030 GAQA---SPKNIVESITGQLSPVKDPEKLLQDMDVNRLRAVIYRDVEETKQAQFLSLAIVYFISV 2091
|.|: :.|..:|:....:||:|||::||||:|:|||||.::|||:::||||||:||:||||||
Zfish 1475 GLQSVSTASKTTIENFPSNVSPIKDPDRLLQDVDINRLRAAVFRDVDDSKQAQFLALAVVYFISV 1539
Fly 2092 LMVSKYRDILEPPAEPQIQRQSPVLQRTAGGEAASARPLFPQWSHHVYPQFLPESHQNHNSNMQH 2156
|||||||||||| ||..| :|:.:|
Zfish 1540 LMVSKYRDILEP-------------QRETG-------------------RFINQS---------- 1562
Fly 2157 QQQQQQQQQHQQQQHYYQQQQQQQVVHNHSHHHMTAAYYQQQQHQQVAAGQQQHSPTPLATHSTS 2221
..|.:|...:|
Zfish 1563 -----------------------------------------------GRGIRQEINSP------- 1573
Fly 2222 SSASSTATSQPASSSSLSSLASQSQQQSHRQLHKQQQQQQQQQQQQQPHYHPHQPHYGLINGHQQ 2286
|:|..| ||.:.|::::...|..:|:...
Zfish 1574 -----TSTDHP-------SLLTDSRKEALGVLESRQESSL------------------------- 1601
Fly 2287 HPQLNGKHYAENGSTAGYHPHSHPHPHGGYMRNGDTSTLQQNGMPDYQAVGLMNGH----GSGGT 2347
||| .:|:.|.|...:|||. ..||.
Zfish 1602 -------------------PHS------------------DSGLGDDQVSSVMNGADLDLAMGGP 1629
Fly 2348 GNNNNSSLMNNMRNLRNGGGANSSSS--PPGSHQVIQGVATAGAVN-ANAAVGVGMGGAVGVGMG 2409
|..|.|...:.:: |.|..| .|.|.:.::..::..::| ||. |:.:.
Zfish 1630 --NGMSGLFCTLSSV-----ARSQESLIEPSSVEHLKTASSISSINQANK----------GINVK 1677
Fly 2410 GVAGGLDGGVVYKTSAINNNYRYNGRNA----SAGTGGRQIQDSDYEIIVVDENNPSVLADNDSH 2470
.:...|....|..|.:......|..:.| :......|....|..::|..:..||.|..|...
Zfish 1678 EILKSLVAAPVETTESGTEALPYPEQQAMKREAQAMMPMQFHSFDRSVVVQAKKPPSGLTVNTVG 1742
Fly 2471 SSGPPS-IKANQTTTIATTTTTTATTHINNNNTKTTTSNAPTATIKIQQQPLSPPKPLVPQKLPK 2534
:||..| :.:..|..|....:.|..:.||......|:|::..:.:.
Zfish 1743 TSGSSSALTSGSTPNIFAAASITPKSMINTTGATDTSSSSSASFVN------------------- 1788
Fly 2535 SVDSDVGSLNMNSTENEVPEVESSSEILIDDHKPSHSNDESWTDVNLNEDAAVQAASAGIVVGLV 2599
.:|...:|.|::.:
Zfish 1789 -----------GATSKNLPAVQTVA---------------------------------------- 1802
Fly 2600 DNRGNVISDKHDPSHHNQQQQQQAGIIGQQQQHGSLGHSERGDKPDSEISVVRVPDGYGGAGSGG 2664
Zfish 1803 ----------------------------------------------------------------- 1802
Fly 2665 GVNSGQGQGVPSNQRPRPEELPMKAPALVAQLPLTTPSREASLTQKLEIALGPVCPLLREIMVDF 2729
|.||: .....|:|.|||.||..|.||||||.|||
Zfish 1803 ---------------PMPED----------------TMENMSITTKLERALEKVAPLLREIFVDF 1836
Fly 2730 APFLSKTLVGSHGQELLMEGKGLTTFKNSHSVVELVMLLCSQEWQNSLQKHAGLAFIELINEGRL 2794
|||||:||:||||||||:| ||...|:|.|||||||||||||||||:||:||||||||||||||
Zfish 1837 APFLSRTLLGSHGQELLIE--GLVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRL 1899
Fly 2795 LSHAMKDHIVRVANEAEFILNRMRADDVLKHADFESQCAQTLLERREEERMCDHLITAARRRDNV 2859
|.||||||||||||||||||||.||:||.|||:|||.|||...:|:|||.||||||:||:.||:|
Zfish 1900 LCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESSCAQYAADRKEEETMCDHLISAAKHRDHV 1964
Fly 2860 IASRLLEKVRNIMCNRHGAWGDSSSTSSG-GAIVGAVQKSPYWKLDAWEDDARRRKRMVQNPRGS 2923
.|::|.:|:.||:.|:|||||.::..||. .......|:..:|:||.||||.|||:|.::||.||
Zfish 1965 TANQLKQKILNILTNKHGAWGAAAQRSSCLFPFSSQQQQHDFWRLDYWEDDLRRRRRFIRNPFGS 2029
Fly 2924 SHPQATLKAALENGGP-EDAILQTRDEFHTQIAVSRTHPSGQHNGELL----DDAELLIEDRELD 2983
:|...|.| :||:.|| ||..|:.|..|..|.:||:...: ||: |||..|::::|:|
Zfish 2030 THLDITCK-SLEDYGPEEDEALRGRKGFRGQASVSQNTET-----ELMLEGDDDAVSLLQEKEVD 2088
Fly 2984 ---------LDLT-GPVNISTKARLIAPGLVAPGTVSITSTEMFFEVDEEHPEFQKIDGEVLKYC 3038
:::: |||.:||.|:||||..||.||:|||:||::|||||:.|.|::||.:||.|.
Zfish 2089 NLAASLYPRVNVSRGPVVLSTPAQLIAPVTVARGTLSITTTEIYFEVDEDDPAFRRIDAKVLVYS 2153
Fly 3039 DHLHGKWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVKKVIKALPRVGVGIKYGI 3103
:.|||||.|||:||:|:||:||||.|||||:|:|||::|.||||.|||||:.:||.||||..||:
Zfish 2154 EGLHGKWMFSEIRAVFTRRFLLQNTALEIFMANRTSVMFNFPDQPTVKKVVYSLPCVGVGTSYGL 2218
Fly 3104 PQTRRASMMSPRQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESK 3168
||.||.|:.|||||.::|||||:||||||||||||||||||||||||||||||:|||||||:||:
Zfish 2219 PQARRISLASPRQLFKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNFESE 2283
Fly 3169 DLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWDSDTIPPFHYGTHYSTAAFTLNWLVRVEPF 3233
:|||::|||:||||||||||||.|..::.:||||||.:| ||.||.||||||..||:||||:|||
Zfish 2284 ELDLTVPSNFRDLSKPIGALNPKRAVFYADRYESWDEET-PPCHYTTHYSTANSTLHWLVRIEPF 2347
Fly 3234 TTMFLALQGGKFDYPDRLFSSVSLSWKNCQRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGA 3298
||.||...|.|||:|:|.|||::.||::|||||:||||||||:|:|||||.||:||.||.|:||.
Zfish 2348 TTFFLNANGNKFDHPNRTFSSIARSWRHCQRDTADVKELIPEFYYLPEMFVNSNGYCLGDRDDGV 2412
Fly 3299 LVDDIELPPWAKSPEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEG 3363
.|.|:|||.|||.||:|||||||||||||||||||||||||||||||||||.||.|||::|||||
Zfish 2413 PVCDVELPAWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAARALNVFHHLTYEG 2477
Fly 3364 SVDLDGVL-DPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHL-----SPMMF-SAMPEDLCQ 3421
||:||.:. ||.:|||.|.||::.||:|||||:|||||||||||| ||:|| ..|.:|:..
Zfish 2478 SVNLDSLASDPPLREATEAQIQSVGQSPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIM 2542
Fly 3422 MLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQP 3486
:|||..||||.|::|||.|.|:||:|||||....||||||: |......:|.|: .....:.|
Zfish 2543 VLKFPSNSPVTHVAANTLPHLTLPAVVTVTCSRLFAVNRWH-NTVGLRGAPGYS---LEQAHHLP 2603
Fly 3487 LTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSNCFVTTVDSRFLIACGFWDNSFRVFATET 3551
:.:|.::| |::..::|.:.|...|.::|.:.|||.|.|:|:::.|||||.||||::::|
Zfish 2604 IEMDSLIA------NNSGTNKRQITDLVDQSIQINTQCFVVTADNRYILVCGFWDKSFRVYSSDT 2662
Fly 3552 AKIVQIVFGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGE----GDVPTPR 3612
.|:.||||||:.||||:||||..|..||||.|||.|.|:|||:|:.| ..|:|: .|.|.||
Zfish 2663 GKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGR-HHIIGDNPNNSDYPAPR 2726
Fly 3613 ATLTGHEQAVTSVVISAELGLVVSGSSNGPVLIHTTFGDLLRSLDPPAEFHSPELITMSREGFIV 3677
|.||||:..|..|.:.||||:::||:..||.|:||..|||||:|:.|.....|.||.:|.||..:
Zfish 2727 AVLTGHDFEVVCVSVCAELGIIISGAKEGPCLVHTITGDLLRALEGPDSCVLPRLICVSSEGHCI 2791
Fly 3678 INYDKGNVAAYTINGKKLRHETHNDNLQCMLLSRDGEYLMTAGDRGIVEVWRTFNLAPLYAFPAC 3742
|.:|:|...:::||||.|.....||:.:.::||.||:.|:|.||.|:||||:..:...||.:|.|
Zfish 2792 IYFDRGQFCSFSINGKLLAQMEINDSTRAIVLSSDGQNLVTGGDNGVVEVWQACDFKQLYVYPGC 2856
Fly 3743 NAGIRSLALTHDQKYLLAGLSTGSIIVFHIDFNRWHHEYQQRY 3785
:||:|::.|:|||:.|:.|:::|||:.|:|||||||.|:|.||
Zfish 2857 DAGVRAMDLSHDQRTLVTGMASGSIVAFNIDFNRWHFEHQNRY 2899
| 
