DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2841 and dos

DIOPT Version :9

Sequence 1:	NP_001284821.1	Gene:	CG2841 / 44529	FlyBaseID:	FBgn0003159	Length:	1239	Species:	Drosophila melanogaster
Sequence 2:	NP_523890.2	Gene:	dos / 38321	FlyBaseID:	FBgn0016794	Length:	878	Species:	Drosophila melanogaster

Alignment Length:	843	Identity:	173/843 - (20%)
Similarity:	276/843 - (32%)	Gaps:	291/843 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   535 SPPPDFSDQQMQKRNAGSLSPGSPLDEIVDELATIINQQRLDTLIKKQPDPQM---VEIESAKPN 596
            |||.....:...:|...:|..|...::...|..|..|.::|..:|......|:   :.:|:.|..
  Fly    13 SPPTKRIWRARWRRRYFTLKQGEIPEQFCLEYYTDHNCRKLKGVIDLDQCEQVDCGLRLENRKQK 77

  Fly   597 RLANFSITTAKSTTRIG------------------------RADSFQAGASGGGTEVASSGRALS 637
            ....|.|.|.|.|..:.                        :::....||.|     |...|. .
  Fly    78 FQYMFDIKTPKRTYYLAAETEADMRDWVNCICQVCHLHDTKQSNELPLGAVG-----ADENRT-Q 136

  Fly   638 HRSSSHVSLNKLEQNGIGLGQRRSSSELSIGESPSLQSPEVIKTILNSRKNSLAESGGSASTPVT 702
            |.|||. .|:...||         ::..|:..|....:|:.          |:..:||||.   .
  Fly   137 HTSSSG-GLSNSTQN---------TTTTSLHSSAGTTAPQA----------SVPNAGGSAQ---L 178

  Fly   703 EQPKIIKQ--LESLAKEQSSVDGVK-------------DISSSRSE---ASQQSPTPVPKKSNPG 749
            .:|.:|::  :.|.|...:| |.|.             |.:..:.|   |:||.|.|.|..:
  Fly   179 RRPAVIEEQPMPSNAGNNNS-DSVYVNTEYSNRETMLCDANFDQQELLSAAQQQPPPSPATA--- 239

  Fly   750 VEKPTSPTFRAVQEPYPSSPALQKSSPAV-------QEQRTSPVERPSLPPAVKSVEEQAVSLHQ 807
                          .|.:..||.::..|.       |:|:.:.....|....|:.:.|..|...|
  Fly   240 --------------LYLNHSALIQAQAAAAAAEQLQQQQQQAARLAVSANGVVRKLPEHLVLTQQ 290

  Fly   808 --KEIVVQKE-----SPPLESMKESFVIVSKM---SPPAVKKVPDPFPKVEAVKEESSGNESSQS 862
              .|...|:.     ||.|.:....::.:|:.   ||..:..||.|                 .:
  Fly   291 TLAEAAAQQHSSVQASPALSTASGPYIPISECFSGSPRFLPGVPLP-----------------GA 338

  Fly   863 TITPPNTPATPVS----------------PVNLRN-----PNNTMAEIEQ-------SQRDEPAP 899
            .:..||.|.||::                .:||.|     |..|...::|       .||.:...
  Fly   339 DLAIPNNPTTPLNNLDPKFYDTPRSHNNIGLNLTNDQSYSPKITNLSLQQLANNNASKQRSDSDS 403

  Fly   900 SS---------KPLP---TTYRYSGPPSINF------ATWSERPKSTVAIKNEGDYIFGGAGKSQ 946
            .|         .|||   ...|.:.|...:.      .|:|:|...   :..||..|...|.||.
  Fly   404 ESVFTDDDEWAHPLPLRENVDRSTRPSDSSIENESFVLTYSQRFSK---MPEEGGAIVPPAEKSS 465

  Fly   947 QLTSPPSKLTIGVASPILRMGIPQ-GKEYHVPITVKPLKDE---ILENQQQEKKEKPEVQELKDQ 1007
            :|.        |.||      :|: |.:..:....|.||::   ||:.::.||..: ::.:|.|.
  Fly   466 KLA--------GAAS------LPEAGDQGTLDKLAKVLKNKNNLILDFKENEKIPR-DLPQLSDT 515

  Fly  1008 EIEKESVSVKVKPKTPVKPVQKR------IEKPLDQDQNSLQNHSSTLPRPAKSNRFTLPAAQNN 1066
            |....::            |.:|      ||:..|            :||..:.     |....|
  Fly   516 ENTSPAI------------VARRNAHSAFIEESYD------------IPRSHQQ-----PYYNVN 551

  Fly  1067 QMVSHLTMNSLPRPVSSLERNRPV--------------------EANP---------APAPFGQS 1102
            |::..       |||:|...:.|:                    .|||         |.:|....
  Fly   552 QLLGE-------RPVTSPHNSNPIAASTPNLMAADLGAVAAISAAANPGLMGEAQAVASSPTSAR 609

  Fly  1103 TLRRTGFKERMLAKEQQE------QEQA------LRIRVSVNESIPSSATAPKSPPESKPAPPSI 1155
            ||.|..:......|.:..      .|||      .:::..|...:|   .....|||..||.|.:
  Fly   610 TLPRHCYTNAAPTKMEGNVFRYDFMEQADCPPVNRKLKPKVAGGLP---VVEDKPPEEFPAKPPV 671

  Fly  1156 SGYVALKSTKVEVKLQEPETKPVSLQVKLKP---------TVQPATTPSPPPPPPALQPVKTN 1209
             |...|.:.....:||:| ..|.|:..|.||         |:.|||..|...|...:.|.:|:
  Fly   672 -GVDQLTNKLGAAQLQQP-IGPPSVDRKCKPNAYKLGNSATMSPATRRSSGAPLSMVLPHETD 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2841	NP_001284821.1	Ehrlichia_rpt	372..958	CDD:118064	105/530 (20%)
dos	NP_523890.2	PH_Gab2_2	2..115	CDD:241535	19/101 (19%)
dos	NP_523890.2	PH	6..113	CDD:278594	19/99 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3751
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900