DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2841 and Apbb1ip

DIOPT Version :9

Sequence 1:	NP_001284821.1	Gene:	CG2841 / 44529	FlyBaseID:	FBgn0003159	Length:	1239	Species:	Drosophila melanogaster
Sequence 2:	NP_001094047.1	Gene:	Apbb1ip / 307171	RGDID:	1304795	Length:	664	Species:	Rattus norvegicus

Alignment Length:	741	Identity:	144/741 - (19%)
Similarity:	233/741 - (31%)	Gaps:	262/741 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   667 IGESPSLQSPEVIKTILNSRKNSLAESGGSASTPVTEQPKI----------IKQL-ESL-AKEQS 719
            :||| :....::..|:| ...:.|.:|.|..:.|..| ||.          .|.| ||| |.|..
  Rat     1 MGES-NEDIDQMFSTLL-GEMDLLTQSLGVDTLPPAE-PKPPREEFNFSVGFKDLNESLNALEDQ 62

  Fly   720 SVDG-----VKDIS-------SSRSEASQQSPTPVPKKSNPGVEKPTSP-------------TFR 759
            .:|.     |.|||       .::.|:||........:::.|  :.|:|             .:.
  Rat    63 DLDALMADLVADISEAEQRTIQAQKESSQNQGHSALLEASDG--QGTAPRGYGANAAAFDVSDYE 125

  Fly   760 AVQEPYPSSPALQKSSPAVQEQRTSPVERPSLPPAVKSVEEQAVSLHQKEIVVQKESPPLESMKE 824
            ....|.|:.|.|....|.           |..||...|.||:.......:|.:     .||.:||
  Rat   126 EALPPPPADPMLDLLPPP-----------PPPPPKPLSKEEEEALAKADKIKL-----ALEKLKE 174

  Fly   825 SFVIVSKMSPPAVKKVPDPFPKVEAVKEESSGNESSQSTITPPNTPATPVSPVNL---------- 879
            :          .|||:         |.:...|:.|::|.:......|..|.. ||
  Rat   175 A----------KVKKL---------VVKVHMGDNSTKSLMVDERQLARDVLD-NLFEKTHCDCNV 219

  Fly   880 -----------------RNPNNTMAEIEQSQRDEPAPSSKPLPTTYRYSGPPSINFATWSERPKS 927
                             .:..|.:..:....||                   :.|...:.|:.:.
  Rat   220 DWCLYEIYPELQIERIFEDHENVVEVLSDWTRD-------------------TENRVLFLEKEEK 265

  Fly   928 TVAIKNEGDYIFGGAGKSQQLTSPPSKLTIGVASPILRMG-------IPQ----------GKE-- 973
            ....||..::.....||.::.::  .|:.......:|...       :|:          ||:
  Rat   266 YAVFKNPQNFYLDNKGKKEKESN--EKMNAKNKEYLLEESFCGTSIIVPELEGALYLKEDGKKSW 328

  Fly   974 ------------YHVPI-TVKPLKD----------EILENQQQEKKEKPEVQE---LKDQEIEKE 1012
                        |:||. ..|..:|          .|....|.:.|.|.....   ||..:|:||
  Rat   329 KRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGIQCKMKYKAPTDHCFVLKHPQIQKE 393

  Fly  1013 SVSVKVKPKTPVKPVQK-----RIEKPLDQDQNSLQNHSSTLPRPAKSNRFTLPAAQNNQMVSHL 1072
            |..:|.......:.:.:     ||.|   ..:....|:...:.|...::|:|           :|
  Rat   394 SQYIKYLCCDDARTLSQWVMGIRIAK---YGKTLYDNYQRAVARAGLASRWT-----------NL 444

  Fly  1073 TMNSLP-RPVSSL-----ERNRPV-EANPAPAPFGQSTLRRTGFKERMLAKEQQEQEQALRIR-- 1128
            ...:.| :|.:.|     :.|.|: :|.|:|.|..:.||.:|        :..::::|.|...
  Rat   445 GTATTPAQPAAGLKTGTSQPNGPMPQAAPSPGPPLRETLTQT--------ETTKDEKQGLANHSP 501

  Fly  1129 -VSVNESIPSSATAPKSPPESK-------PA-PPSISGYVALKSTKVEVKLQEPETKPVSLQ--- 1181
             .|.....|.|:..|..||..:       || ||...|..:...|........|...|...:
  Rat   502 GASRENHRPKSSLLPPPPPVRRSSDTCGSPALPPKAKGPGSCTFTAQPENFLPPPPPPPPQEDDN 566

  Fly  1182 -VKLKP---------------------TVQPATTPSPPPPPPALQ----------------PVKT 1208
             :.|.|                     ||:.:..|.||||||.|.                |.|.
  Rat   567 SMLLPPPPPLAYLDEPPDFVPPPPPPATVEDSALPPPPPPPPCLSQEMTKSSPLPAKKLPVPPKR 631

  Fly  1209 NGGRSGPTAP-----DPRSQLLDAIR 1229
            ...:..|.||     |..|.|:.|::
  Rat   632 QENQGLPGAPRNTEQDFMSDLMKALQ 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2841	NP_001284821.1	Ehrlichia_rpt	372..958	CDD:118064	67/354 (19%)
Apbb1ip	NP_001094047.1	RA_MRL_RIAM	185..266	CDD:340554	12/100 (12%)
Apbb1ip	NP_001094047.1	PH_APBB1IP	308..429	CDD:269961	23/123 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3751
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900