Protein Alignment robo2 and CG15312

DIOPT Version :10

• Sequence 1: NP_001259868.1
• Gene: robo2 / 44522
• FlyBaseID: FBgn0002543
• Length: 1519
• Species: Drosophila melanogaster
• Sequence 2: NP_001245603.1
• Gene: CG15312 / 31940
• FlyBaseID: FBgn0030174
• Length: 464
• Species: Drosophila melanogaster
• Alignment Length: 578
• Identity: 103/578 - (17%)
• Similarity: 172/578 - (29%)
• Gaps: 218/578 - (37%)

  Fly   702 SGDVVELSNASVVDSTSMKLTWQIINGKYVEGFYVYARQLPNPIVNNPAPVTSNTNPLLGSTSTS 766
            :|.|:.|.|.|..|:                |.||....:|.|                .:|:||
  Fly    68 TGRVLVLRNVSTTDA----------------GIYVCFASVPRP----------------STTATS 100

  Fly   767 ASASASASALISTKPNIAAAGKRDGETNQSGGGAPTPLNTKYRMLTILNGGGASSCTITGLVQYT 831
            |:.|........|:|   ...:.||:     |.:.:|.:.:.:           ...:...|:|.
  Fly   101 ATTSPQNLQDKETRP---LEDEDDGQ-----GESVSPKDDQLK-----------EAEMEEEVEYL 146

  Fly   832 LYEFFIVPFYKSVEGKPSNSRIARTLEDVPSEAPYGMEALLLNSSAV--FLKWKAPELKDRHGVL 894
            .::              ....|.||:       |..:..|...:|.:  ||.|:..:.:.....:
  Fly   147 AHQ--------------RTKLIVRTV-------PGPVSQLYFKASTILGFLIWRFNKTQSGGYPV 190

  Fly   895 LNYHVIVRGI---------DTAHNFSRI-LTNVTIDAASPTLVLANLTEGVMYTVGVAAGNNAGV 949
            .::....|.:         ...|.:||: ..|:..:...  :.:..|.....|...:.|.|..|.
  Fly   191 RSFTAEYRNVSYKTPPANASFEHAWSRMDPINIAFNVRQ--MEVYRLAPNTTYEFRIWANNELGS 253

  Fly   950 GPY------CVPATLRLD------PITKRLDPFINQRYPINQDHVNDVLTQPWFI---ILLGAIL 999
            |..      .:|.|...|      |.....||.|                  |.:   |:||.:
  Fly   254 GEVVTTNVTTLPETKEEDLIRLIKPDLDNFDPRI------------------WIVAVSIVLGTL- 299

  Fly  1000 AVLMLSFGAMVFVKRKHMMMKQSALNTMRGNHTSDVLKMPSLSARNGNGYWLDSSTGGMVWRPSP 1064
              ::|:.|..:.:.::.....|..|                                      ..
  Fly   300 --VILAIGLCIVLSKECYQSAQMEL--------------------------------------QD 324

  Fly  1065 GGDSLEMQKDHIADYAPVCGAPG-SPAGGGTSSGGSGGAGSGASGGDDIHGGHGSERNQQRYVGE 1128
            |.||:|:..:.|.:       || |.:.||...||.|            |||...:::    .||
  Fly   325 GWDSIELIPNIILN-------PGFSESDGGPEPGGQG------------HGGSAGDQD----AGE 366

  Fly  1129 YSNIPTDYAEVSSFGKAPSEYGRHGNASPAPYATSSILSPHQQQQQQQPRYQQRPVPGYGLQRPM 1193
                 .|..:|:........:|:|....|.|...   |.|...:.|.|
  Fly   367 -----DDDDDVAMPFPRTIIFGQHHRTPPPPRLH---LPPQHHRHQNQ----------------- 406

  Fly  1194 HPHYQQQQHQQQQAQQTHQQHQALQQHQQLPPSNIYQQMSTTSEIYPTN-----TGPS 1246
             .|:.|..|||.| ||.|..|  |::.......:..::...|.|.:...     |||:
  Fly   407 -SHHHQYHHQQNQ-QQHHHHH--LRRQDDDDDDDYEEEHEPTMERFKRKVSVFFTGPT 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
robo2	NP_001259868.1	IgC_1_Robo	91..185	CDD:409490
		Ig strand A	91..95	CDD:409490
		Ig strand A'	98..103	CDD:409490
		Ig strand B	107..115	CDD:409490
		Ig strand C	121..126	CDD:409490
		Ig strand C'	129..131	CDD:409490
		Ig strand D	139..142	CDD:409490
		Ig strand E	145..151	CDD:409490
		Ig strand F	162..170	CDD:409490
		Ig strand G	173..185	CDD:409490
		IgI_2_Robo	192..279	CDD:409389
		Ig strand A	192..195	CDD:409389
		Ig strand A'	197..201	CDD:409389
		Ig strand B	205..212	CDD:409389
		Ig strand C	220..225	CDD:409389
		Ig strand C'	227..230	CDD:409389
		Ig strand D	237..241	CDD:409389
		Ig strand E	244..250	CDD:409389
		Ig strand F	257..265	CDD:409389
		Ig strand G	268..279	CDD:409389
		Ig	286..370	CDD:472250
		Ig strand B	300..304	CDD:409353
		Ig strand C	313..317	CDD:409353
		Ig strand E	336..340	CDD:409353
		Ig strand F	350..355	CDD:409353
		Ig strand G	363..366	CDD:409353
		Ig_3	373..457	CDD:464046
		Ig	480..566	CDD:472250
		Ig strand B	496..500	CDD:409353
		Ig strand C	509..513	CDD:409353
		Ig strand E	533..537	CDD:409353
		Ig strand F	548..553	CDD:409353
		Ig strand G	561..564	CDD:409353
		COG3979	586..>800	CDD:443178	21/97 (22%)
		FN3	588..681	CDD:238020
		fn3	864..952	CDD:394996	17/99 (17%)
CG15312	NP_001245603.1	Ig	39..90	CDD:472250	9/37 (24%)
		Ig strand B	43..47	CDD:409358
		Ig strand C	52..56	CDD:409358
		Ig strand F	84..89	CDD:409358	2/4 (50%)