Protein Alignment robo2 and DIP-lambda

DIOPT Version :9

• Sequence 1: NP_001259868.1
• Gene: robo2 / 44522
• FlyBaseID: FBgn0002543
• Length: 1519
• Species: Drosophila melanogaster
• Sequence 2: NP_001334747.1
• Gene: DIP-lambda / 26067049
• FlyBaseID: FBgn0267428
• Length: 548
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 123/551 - (22%)
• Similarity: 195/551 - (35%)
• Gaps: 118/551 - (21%)

  Fly   256 DGRYQC-----VVKNVVGTRESATAFL-----KVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDP 310
            :|...|     ::|.:..|:..|.|.:     ...:.|..:....|.|..:|..:.|.|.:....
  Fly    13 NGTLACSIAFILIKAITITKCHAVAHIHGKGESEEIDPQFLAKLSNTTVPIGRDISFTCVVDNLG 77

  Fly   311 LPDVLWRRTASGGNMPLR--------RVHVLEDR----SLKLDDVTLEDMGEYTCEADNAVGGIT 363
            ...|.|.::.|...:.:.        |:.|..:.    .|.:..|.:.|.|.|.|:. |.....:
  Fly    78 HYRVAWIKSDSKAILGIHTHMVSLNPRLSVTHNGHNTWKLHISRVQINDSGSYMCQV-NTDPMKS 141

  Fly   364 ATGILTVHAPPKFVIRPKNQ----LVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGR 424
            .:|.|.|..||..:..|::.    :.:.|..:...|...|.|||.:.|..|....::|  ..|||
  Fly   142 LSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREAGKEIIL--RTDGR 204

  Fly   425 MEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAV-GSVSSRTVVSVDTQFELPPPIIEQGPVNQ 488
            .:..........|.:....|.|.|. ..|.|.|.: .|||.|..|.|:..     |.::  .::|
  Fly   205 DKTGFKSVEGERLVLTNVQRSDMGG-YNCIASNGIPPSVSKRFNVYVNFS-----PTVK--AISQ 261

  Fly   489 TL--PVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAGA--------LTISDLQRH 543
            .:  ||:..|.|.|.....|.|...||.....|.:....:.|:|:...        |||..|.:
  Fly   262 LVGAPVEREVTLECIVEVFPKPLNGWYRSEGNIKLHNGNKYNISEEVINIYTWHLNLTIRHLTK- 325

  Fly   544 EDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGP----PGK-----PQMVEK 599
            .|.|.|:|.:.|..|||  ...:||.....|       |:|:|.|.|    .||     |...:|
  Fly   326 SDFGTYSCSSVNALGKS--ESLIRLQELRLP-------PKLTTTPTPHMQTTGKSRRKHPASHKK 381

  Fly   600 GENSV------------------------TLSWTRSNKVGGSSLV---GYVIEMFGKNETD---- 633
            |.|.|                        .|.:|.|.   .|::|   |::..|..|.:.:
  Fly   382 GLNEVLRFQETHFANQIQQENEDHNEGFDLLKFTNSE---NSNIVLESGHINSMINKEDVNIYHP 443

  Fly   634 ---GWVAVGTRVQNTTFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSEPITVG-----TRYFNSG 690
               |        |..|...:|.:|.....:::....|...:|.|..:..:...     .|.|:|
  Fly   444 KQYG--------QEKTNKPSGTIPSTRTPWILTNAGSQRPALTSYATVALITSFWLFFWRVFHS- 499

  Fly   691 LDLSEARASLLSGDVVELSNASVVDSTSMKL 721
            ||....|.|.:...||.....|..::.:..|
  Fly   500 LDWDAIRVSSVVHHVVVFKRRSYFEAPNYAL 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
robo2	NP_001259868.1	Ig1_Robo	90..185	CDD:143317
		I-set	91..184	CDD:254352
		I-set	190..279	CDD:254352	6/32 (19%)
		Ig2_Robo	193..279	CDD:143201	6/32 (19%)
		I-set	283..370	CDD:254352	20/98 (20%)
		Ig	300..370	CDD:299845	16/81 (20%)
		Ig	388..>457	CDD:299845	18/68 (26%)
		I-set	479..561	CDD:254352	25/91 (27%)
		Ig	496..561	CDD:143165	21/72 (29%)
		FN3	588..681	CDD:238020	25/135 (19%)
		FN3	<817..856	CDD:238020
		fn3	864..952	CDD:278470
DIP-lambda	NP_001334747.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010