Protein Alignment clmnb and Msp300

DIOPT Version :10

• Sequence 1: NP_001003605.1
• Gene: clmnb / 445211
• ZFINID: ZDB-GENE-040801-124
• Length: 687
• Species: Danio rerio
• Sequence 2: NP_001188695.1
• Gene: Msp300 / 3771968
• FlyBaseID: FBgn0261836
• Length: 13540
• Species: Drosophila melanogaster
• Alignment Length: 820
• Identity: 149/820 - (18%)
• Similarity: 277/820 - (33%)
• Gaps: 243/820 - (29%)

Zfish    11 QVGKEKKCKQR-------------------------AQDERHAVQERTFTKWINMQLKSCEPPLQ 50
            :.|||||.|.:                         .:|.....:..||: |.::..:|.|.|..
  Fly  7506 KAGKEKKSKVQNVEESILESDVPLSVVEPIIGFTTVQKDVPPKTESHTFS-WSSIVAQSVEVPRT 7569

Zfish    51 V-HHLFTDIQDGKVLMALLEELSGCNLLDKF--RPFPHRIFRLNNISKVLNFLKDRNISLVNIEA 112
            : .|:  :.:.|.:...:.:|.:...:::..  :|.|.:      ..|::..::......|.:..
  Fly  7570 IPKHV--ESKTGGIQNFIAQEQNYSTVVNDSVKKPKPKK------EKKIVQPIQQPTGESVPVRK 7626

Zfish   113 DDIADGSPSAV---LRLIWNIIVYYQIKQVTRSLEKSPSTFSLLSLPCDSDSSGRSSPASPGDDI 174
            |.:.:|...||   ..|.|:.||.:.| .:|.:..::....::..:..|..||.:.
  Fly  7627 DHMREGVTKAVPEPQTLSWSSIVSHNI-DLTPTFTENRVIEAVDEINPDDSSSNQE--------- 7681

Zfish   175 FGTLP---SKGKKSLKNLKYRGTAIKTLLSW---------AQNCTAKYGVEIRDFGKS--WRSGL 225
             |.||   .:.|:..|..|.|...|:|.:.:         |.:.|.::.:::....|.  |.|..
  Fly  7682 -GELPIHVDERKRKPKKDKKRDQNIETSVVYEEIPETERVAVSSTPEFSIQLPAPTKPSVWSSSD 7745

Zfish   226 AFVALVK--------FFCPEFVHMRKALSSEPR---LNMETAFRAAQEWLGIPPLLNP---DDVA 276
            .:..:||        ....:.:..|:.:.|||:   :.::|    .::.|..|..:.|   .|.|
  Fly  7746 TYAEVVKKSGYNNNTNIKYQKIEAREPIKSEPKHTFVEVQT----HEDLLEFPDPIIPAIERDEA 7806

Zfish   277 VHSPDEQSIITYIAQFLECCPGHDEDAMSTDSSRGTPNSTERWDRVSTDSDSCVFPSNV----ST 337
            :..|.:.|....:          |||.:         :..|.|.:..|||........:    |.
  Fly  7807 LEKPSQLSWKDLV----------DEDDV---------DPLESWHKGETDSVEIKTQKPIQERHSR 7852

Zfish   338 EALRDLYNLSETSEEEQTYHTGDQESLSVCQENIRDLAARSE--SLLNV-----KKTS------- 388
            .:::....::|...|.|:....|||.|.:..:......:||:  ...|:     ||.|
  Fly  7853 VSVKPEIQITEVVTETQSQSETDQEFLEITSKKRNRSRSRSQQSQASNIDEKHQKKKSKKPKNTV 7917

Zfish   389 ------TGGQCCDSIAWRKRWIGSLEDDG-------NCSEVSKEAVYSLSVLDSDEEDAFSYI-- 438
                  ...:..:.:...|..:.|:|:..       |.|.:|..|:.:.:|     .:...:|
  Fly  7918 PKAPAQQPTEAPEDVQPPKESVPSVEEPSPPPAPSPNTSGMSWAAIAAHNV-----PEPVQHIRP 7977

Zfish   439 LELDHKDSGLESNIDFGLNTVMDSQAVEFDLNVASIFETQESEIKYCCCEAQRNLKATDVSVRSG 503
            |:.:.|.:.:|.         :.....|..:|:...|||.|.:.|....:::|.| .|||.....
  Fly  7978 LQAEAKPTVVED---------VRKSTNEHTVNIPITFETTEPKTKKPKQKSKRKL-PTDVVDFIN 8032

Zfish   504 GGKCTNKITLDQVRPTKSNILTE---------NN-----------------CDEKTLPASDTLLM 542
            ..|     ::.||..:|..|:.|         ||                 .:.:..|.|:: .|
  Fly  8033 AEK-----SIHQVIASKPEIVEEPGSIIVEDVNNTLTSWEIKTPLAPFEFVAESEVEPVSES-HM 8091

Zfish   543 NQNSIEKIENNFKLY------------------TDERPDLNCSL-----------KMKESDSADA 578
            ....:||:.....:.                  |......|.|:           |..|.....|
  Fly  8092 EDLPVEKVLKTEPIVESTAVDESKTTTTVTTTTTTTETTSNVSIPEEPKKVVEPEKKPEEPKKPA 8156

Zfish   579 FT------HSNGTDDAFVHLDNCVDEDKLREELFLCPVKENLLDNDQYEQNNVLDRSVLDG---- 633
            :.      .||...|......|..|::   ||....|:||..|..:..|:..:::.||:|.
  Fly  8157 YAGLPVDDSSNSWMDVLDEPMNFSDDE---EEPVPEPLKEETLVEEVVEEKPIVEVSVVDDSKSI 8218

Zfish   634 -----------------ITEEP--AVSHAKRKEGLDQASY 654
                             |.|||  .|...|:.|...:.:|
  Fly  8219 TTVTTTTTTTETISELPIPEEPKKVVEPEKKPEEPKKPAY 8258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clmnb	NP_001003605.1	CH_SF	25..138	CDD:469584	22/118 (19%)
		CH_CLMN_rpt2	192..297	CDD:409094	22/129 (17%)
Msp300	NP_001188695.1	SPEC	17..220	CDD:238103
		EnvC	194..>393	CDD:443969
		PTZ00121	<1704..1881	CDD:173412
		SPEC	9546..9732	CDD:413338
		rne	<10668..10827	CDD:236766
		SMC_prok_B	11268..12195	CDD:274008
		YhaN	11930..12426	CDD:443752
		SMC_prok_B	<12205..12954	CDD:274008
		YhaN	12817..>13241	CDD:443752
		SPEC	13196..13374	CDD:238103
		KASH	13484..13540	CDD:463142