DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cv and twsg1a

DIOPT Version :9

Sequence 1:	NP_001284902.1	Gene:	cv / 44510	FlyBaseID:	FBgn0000394	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_571872.2	Gene:	twsg1a / 84037	ZFINID:	ZDB-GENE-010509-2	Length:	217	Species:	Danio rerio

Alignment Length:	228	Identity:	81/228 - (35%)
Similarity:	118/228 - (51%)	Gaps:	43/228 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IVLLAIVCFYGTVESCNEVVCASIVSKCMLTQSCKCELK--NCSCCKECLKCLGKNYEECCSCVE 74
            |.:|.::.....:..||:.:|||.||||:|...|:|..:  ||||||||:.||...:||||.||.
Zfish    12 ISVLFLLSSLSLISGCNKALCASDVSKCLLQGLCQCRPQEGNCSCCKECMLCLSALWEECCDCVG 76

  Fly    75 LC-PKPNDTRNSLSKKSHVEDFDGVPELFNAVATPDEGDSFGYNWNVFTFQVDFDKYLKGPKLEK 138
            :| |:..:...:.||.:..|.:..:|.||.|:.   |||: ..|..|.:|          |..|:
Zfish    77 MCNPRSYNDSPATSKSTVEELYRPIPSLFRALT---EGDA-PINMMVVSF----------PVAEE 127

  Fly   139 DGHY-----FLRTND---KNL--------DEAIQERDNIVTVNCTVIYLDQCVSWNKCRTSCQTT 187
            ..|:     ||.|.|   :|:        |:|:          |||:|.|.|||..:|:..|::.
Zfish   128 LSHHENLVSFLETLDSQSQNISLPTSSAQDDAL----------CTVVYFDDCVSIRQCKQYCESM 182

  Fly   188 GASSTRWFHDGCCECVGSTCINYGVNESRCRKC 220
            |.|..||||:.||||:|..|::||....:|..|
Zfish   183 GGSKYRWFHNACCECIGPECLDYGSKTVKCMNC 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cv	NP_001284902.1	Tsg	87..221	CDD:398376	49/150 (33%)
twsg1a	NP_571872.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583805
Domainoid	1	1.000	79	1.000	Domainoid score	I8599
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4353
OMA	1	1.010	-	-		QHG47007
OrthoDB	1	1.010	-	-		D1254178at2759
OrthoFinder	1	1.000	-	-		FOG0003932
OrthoInspector	1	1.000	-	-		mtm6400
orthoMCL	1	0.900	-	-		OOG6_108753
Panther	1	1.100	-	-	LDO	PTHR12312
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5846
SonicParanoid	1	1.000	-	-		X3232
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940