DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cv and Twsg1

DIOPT Version :9

Sequence 1:	NP_001284902.1	Gene:	cv / 44510	FlyBaseID:	FBgn0000394	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_075540.1	Gene:	Twsg1 / 65960	MGIID:	2137520	Length:	222	Species:	Mus musculus

Alignment Length:	212	Identity:	80/212 - (37%)
Similarity:	117/212 - (55%)	Gaps:	30/212 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 ESCNEVVCASIVSKCMLTQSCKCE--LKNCSCCKECLKCLGKNYEECCSCVELCPKPNDTRNSLS 87
            :|||:.:|||.||||::.:.|:|.  ..||.|||||:.|||..::|||.||.:|...|.:....:
Mouse    23 QSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPT 87

  Fly    88 KKSHVEDF-DGVPELFNAVATPDEGDSFGYNWNVFTFQVDFDKYLKGPKLEKDGHY-----FLRT 146
            .||.||:. :.:|.||.|:.   |||: ..|||:.:|          |..|:..|:     ||.|
Mouse    88 SKSTVEELHEPIPSLFRALT---EGDT-QLNWNIVSF----------PVAEELSHHENLVSFLET 138

  Fly   147 NDKNLDEAIQERDNIVTV--------NCTVIYLDQCVSWNKCRTSCQTTGASSTRWFHDGCCECV 203
            .::...:.:....|.|..        .|||:|.|.|:|.::|:.||::.|||..||||:.||||:
Mouse   139 VNQLHHQNVSVPSNNVHAPFPSDKERMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECI 203

  Fly   204 GSTCINYGVNESRCRKC 220
            |..||:||....:|..|
Mouse   204 GPECIDYGSKTVKCMNC 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cv	NP_001284902.1	Tsg	87..221	CDD:398376	51/148 (34%)
Twsg1	NP_075540.1	Tsg	87..221	CDD:282516	51/148 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839719
Domainoid	1	1.000	88	1.000	Domainoid score	I7926
eggNOG	1	0.900	-	-		E1_28J21
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4306
Isobase	1	0.950	-	0	Normalized mean entropy	S6699
OMA	1	1.010	-	-		QHG47007
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003932
OrthoInspector	1	1.000	-	-		otm42599
orthoMCL	1	0.900	-	-		OOG6_108753
Panther	1	1.100	-	-	LDO	PTHR12312
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5846
SonicParanoid	1	1.000	-	-		X3232
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.740