DRSC/TRiP Functional Genomics Resources

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Protein Alignment br and ZBTB14

DIOPT Version :9

Sequence 1:NP_001162638.2 Gene:br / 44505 FlyBaseID:FBgn0283451 Length:1011 Species:Drosophila melanogaster
Sequence 2:NP_001137295.1 Gene:ZBTB14 / 7541 HGNCID:12860 Length:449 Species:Homo sapiens


Alignment Length:210 Identity:44/210 - (20%)
Similarity:85/210 - (40%) Gaps:36/210 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 DDTQHFCLRWNNYQSSITSAFENLRDDEAFVDVTLACEGRSIKAHRVVLSACSPYFRELLKSTPC 66
            ||.:...|:..|.|          |.:..|.|:.:..|....:|||.||:|||.||::|.|....
Human    16 DDHKTLFLKTLNEQ----------RLEGEFCDIAIVVEDVKFRAHRCVLAACSTYFKKLFKKLEV 70

  Fly    67 KHPVILLQDVNFM--DL-HALVEFIYHGEVNVHQKSLQSFLKTAEVLRVSGLTQ--QQAEDTHSH 126
            ....::  :::|:  |: ..::.::|..:::|.::.:...:.:.::|.:..|.:  .|..|..| 
Human    71 DSSSVI--EIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFLDKLCSQKRDVSS- 132

  Fly   127 LAQIQNLANSGGRTPLNTH--------TQSLPHPHHGSLHDDGGSSTLFSRQGAGSPPPT---AV 180
              ..:|...|..:..|..:        ||.......|...|.....|:     .|:||..   ..
Human   133 --PDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTV-----EGTPPSQEDGKS 190

  Fly   181 PSLPSHINNQLLKRM 195
            |:....:...:||.:
Human   191 PTTTLRVQEAILKEL 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
brNP_001162638.2 BTB 22..118 CDD:279045 22/100 (22%)
BTB 33..118 CDD:197585 20/89 (22%)
C2H2 Zn finger 712..729 CDD:275368
C2H2 Zn finger 742..763 CDD:275368
ZBTB14NP_001137295.1 BTB_POZ_ZBTB14 18..131 CDD:349513 27/124 (22%)
Nuclear localization signal. /evidence=ECO:0000255 50..66 10/15 (67%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 153..194 9/45 (20%)
C2H2 Zn finger 279..299 CDD:275368
SFP1 <303..383 CDD:227516
C2H2 Zn finger 307..327 CDD:275368
zf-H2C2_2 319..344 CDD:404364
C2H2 Zn finger 335..355 CDD:275368
C2H2 Zn finger 363..383 CDD:275368
C2H2 Zn finger 391..407 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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