Protein Alignment br and psq

DIOPT Version :10

• Sequence 1: NP_001162638.2
• Gene: br / 44505
• FlyBaseID: FBgn0283451
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: NP_001369078.1
• Gene: psq / 36118
• FlyBaseID: FBgn0263102
• Length: 1170
• Species: Drosophila melanogaster
• Alignment Length: 1225
• Identity: 263/1225 - (21%)
• Similarity: 432/1225 - (35%)
• Gaps: 386/1225 - (31%)

  Fly     5 QHFCLRWNNYQSSITSAFENLRDDEAFVDVTLACEGRSIKAHRVVLSACSPYFRELLKSTPCKHP 69
            |:|.|||||||:::||.|:.||:|.:||||||:||..|:|||:|||||||.||::||...|||||
  Fly     8 QYFSLRWNNYQNTMTSVFQQLREDLSFVDVTLSCEHGSLKAHKVVLSACSTYFQKLLLENPCKHP 72

  Fly    70 VILL-QDVNFMDLHALVEFIYHGEVNVHQKSLQSFLKTAEVLRVSGL--TQQQAEDTHS------ 125
            .|:| .|:.|.||..:::|:|.||::|.:..||..|:|||.|::.||  |.:.|:|.:.
  Fly    73 TIILPADIIFTDLKTIIDFVYRGEIDVTESELQGLLRTAEQLKIKGLCETAENADDLNDAATATI 137

  Fly   126 ------HLAQIQNLANS----GGRTP-----------------LNTHTQSLPHPHHGSLHDDGGS 163
                  ..|.:.|:.|:    |..:|                 ...|.|...|...........:
  Fly   138 TVSENIQQAVVGNIVNAAIVPGAPSPSLEQQQQHHQQQQQQQAQEQHQQQQVHAQQQQQQQQQIN 202

  Fly   164 STLFSRQGAGSPPPTAVPSLPSHINNQLLKRMAMMHRSSAAAA--AEETSHAFK------RLRGS 220
            :.|.::.|..|...:        ::.|||...|.....|.|..  |.:|....:      ||:.|
  Fly   203 AALLTQHGVSSGSVS--------LSGQLLSSSASGSSGSLAGGQQASQTPSGLQPTPRKSRLKRS 259

  Fly   221 DN-SLPLSGAVGS--GSNNNSPDLPPLHARSASPQ------QTPADFSTIKHHNNNNTPPLKEEK 276
            .: .|...|..||  ||::.|....|..|....||      |.|....:::...:.|..|:
  Fly   260 KSPDLSSGGGAGSSGGSSSGSTQQQPQPAHHHHPQTILIQGQNPNSIVSLQQTADGNYIPV---- 320

  Fly   277 RNGPTGNG------------NSGNGNGNGNGASNGNGISISDKLGSLTPSPLARAGADDVKSEPM 329
                :|:|            |.|:|:|:| |.::|:|.|
  Fly   321 ----SGSGDDSDAEDHEHEHNHGHGHGHG-GHTHGHGHS-------------------------- 354

  Fly   330 DMVCSNNNANANDEHSNDSTGEHDANRSSSGDGGKGSLSSGNDEEIGDGLASHHAAPQFIMSPAE 394
                        .|||:|...||..|:...                     :.|:    :.|||.
  Fly   355 ------------HEHSHDHEHEHKPNKICK---------------------TEHS----VASPAS 382

  Fly   395 NKMFHAAAFNFPNIDPSALLG--LNTQLQQSGD---------LAVSPQGGSTG---SLLSGVIVP 445
            |.  .:|:.|...:......|  :.||:..:.|         |.:...||..|   ..|.....|
  Fly   383 NS--SSASNNAAGVSGVTSTGQAIVTQIVVARDGKDTKNMTSLGMGMNGGLLGVPMGFLDFTPEP 445

  Fly   446 GGSGGTP--------------------SNSSSNNNNNNSNNQQQKVEQQSSPHQLLQQQHHSTPH 490
            .....||                    ||::...:.:|...||.....||..|.:  ..||:...
  Fly   446 PAPSATPVTVTEHVDLSCNPSTDTRDLSNTTEPLDIDNHLAQQIHRLDQSPMHSI--SHHHTGDE 508

  Fly   491 TNS---PQLKQEQPKSGGGSCKSSDLHIAAGSERSLSRSSQGMPDAGGHSATPSPTAAYHKRERE 552
            :||   ..:|.|..::         .|:|| ...:||::.|.......|..........|:::::
  Fly   509 SNSNLVQHIKSEVIEA---------KHLAA-QHHALSQAQQQHAHHQAHQQHQQHQQQQHQQQQQ 563

  Fly   553 R--------ERERERERERERERSLDHERDLERPGGTGSPPPPPPSHHSHFGQHPLSLLPSHHQL 609
            .        :.:.::::::::::...|::..::.....:..          |.|      ..|..
  Fly   564 HLHAQQLLAQSQLQQQQQQQQQQQQHHQQQQQQAAAAAAAA----------GVH------GQHGG 612

  Fly   610 HATHHELSAA---------------------------AAHHAHAHAHAAHAHALARAGSP---ME 644
            |.||.::..|                           :.|....::..:....:...|||   .|
  Fly   613 HVTHADIGGATVMEIDPSQIKHEPGMIITPEIVNMMSSGHMDMYNSDTSEDSMMIANGSPHDQKE 677

  Fly   645 HHHLLHHRRASLSPSGAVSSASGAGGRGGGAGGPG-GPGGSLLSSVRAQDVA------------- 695
            .|:....::..|..|.......||||.||.:||.| |.|...|.:::.|:::
  Fly   678 PHYTNLDQQHGLGGSVCGPGPGGAGGGGGMSGGAGSGSGEKALDALKNQNMSLTKASAIYGIPST 742

  Fly   696 ----QANRLLLPLP-------------------------LNACHRCDVCGKLLSTKLTLKRHKEQ 731
                :|:|:.:..|                         ::|.......|...||...:.|.:..
  Fly   743 TLWQRAHRMGIETPKKEGGTKSWNEDALQNALEALRSGQISANKASKAFGIPSSTLYKIARREGI 807

  Fly   732 QHLQPLNNAVCNLC-HKVFRTLNSLNNHK---------------SIYHRRQKNHHSYFHHGAGVS 780
            :...|.|.|..... ..:.|.|.::....               ::|.|.::       .|..:|
  Fly   808 RLAAPFNAAPTTWTPEDLERALEAIRAGNTSVQKASAEFGIPTGTLYGRCKR-------EGIELS 865

  Fly   781 QAG-SPGSR--LHQSLSSLSAAAAAANNSV---NVGGGS------------VGGAGGNAVAAAAA 827
            ::. :|.|.  ::::|:|:.....:.|.:.   |:...|            |....|.|:...:.
  Fly   866 RSNPTPWSEDAMNEALNSVRVGQMSINQAAIHYNLPYSSLYGRFKRGKYDVVANTSGVALLNTSG 930

  Fly   828 AAAAAAELL------------------------LSPIVGAAAVAGGTASSTLQLAAAH----QQQ 864
            ....:.|::                        .:|...::|..|......:|....|    |||
  Fly   931 NTTGSIEIIEHSQENSQQFPYSPSPHPPTPQHHSTPQHHSSAQQGPPTPQHMQQHVVHMQQQQQQ 995

  Fly   865 QQQSSP-----------GIVKPCMDFL-XDQQQLLQQLF--HVALNNSAAAAAAAAAAAAAGGSG 915
            |||.||           .:|......: ..|||.|||::  |.....| .:..||....:.||.|
  Fly   996 QQQQSPHPGHHPQHMQQDVVTSSSQVVHSQQQQQLQQIYQHHGTPERSXESLHAATLMGSTGGGG 1060

  Fly   916 GGPGGVGAGPESINGGGQEYGG--------VQGPSGTPTVDLTQLEHAAGGGGFS 962
            |  ||||....|.:.|......        |.|||..|...:|....:|..||.|
  Fly  1061 G--GGVGGVAASTSDGTAASSTPFASISALVSGPSSAPPPPVTASGSSAVSGGTS 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
br	NP_001162638.2	BTB_POZ_BAB-like	31..114	CDD:349624	46/83 (55%)
		C2H2 Zn finger	712..729	CDD:275368	4/16 (25%)
		C2H2 Zn finger	742..763	CDD:275368	2/36 (6%)
psq	NP_001369078.1	BTB_POZ_BAB-like	34..118	CDD:349624	46/83 (55%)
		HTH_psq	717..>747	CDD:283007	2/29 (7%)
		HTH_psq	767..804	CDD:283007	4/36 (11%)
		HTH_psq	821..866	CDD:283007	5/51 (10%)
		HTH_psq	873..916	CDD:283007	6/42 (14%)