Protein Alignment br and ZBTB49

DIOPT Version :9

• Sequence 1: NP_001162638.2
• Gene: br / 44505
• FlyBaseID: FBgn0283451
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: NP_001317554.1
• Gene: ZBTB49 / 166793
• HGNCID: 19883
• Length: 765
• Species: Homo sapiens
• Alignment Length: 988
• Identity: 188/988 - (19%)
• Similarity: 308/988 - (31%)
• Gaps: 348/988 - (35%)

  Fly    33 DVTLACEGRSIKAHRVVLSACSPYFRELLK-STPCKHPVILLQDVNFMDLHALVEFIYHGEVNVH 96
            |..|..:|...|||:.||:|.|.|||.|.: |:..|:.|..|...|...:..:::|:|...::::
Human    26 DCMLVVKGVCFKAHKNVLAAFSQYFRSLFQNSSSQKNDVFHLDVKNVSGIGQILDFMYTSHLDLN 90

  Fly    97 QKSLQSFLKTAEVLRVSGLTQQQAEDTHSHLAQIQNLANSGGRTPLNTHTQSLPHPHHGSLHDDG 161
            |.::|..|.||:.|:|    |......|:.|.....:...|  .|.|
Human    91 QDNIQVMLDTAQCLQV----QNVLSLCHTFLKSATVVQPPG--MPCN------------------ 131

  Fly   162 GSSTLFSRQGAGSPPPTAVPS--LPSHINNQLLKRMAMMHRSSAAAAAEETSHAFKRLRGSDNSL 224
              ||| |.|...:|..|.|.|  .|.|          ::...||.|...:|         .|.|.
Human   132 --STL-SLQSTLTPDATCVISENYPPH----------LLQECSADAQQNKT---------LDESH 174

  Fly   225 PLSGAVGSGSNNNSPDLPPLHARSASPQQTPADFSTIKHHNNNNTPPLKEEKRNGPTGNGNSGNG 289
            |                      .|||       |..:||:..      |..:..|
Human   175 P----------------------HASP-------SVNRHHSAG------EISKQAP--------- 195

  Fly   290 NGNGNGASNGNGISISDKLGSLTPSPLARAGADDVKSEPMDMVCSNNNANANDEHSNDSTGEHDA 354
                         ..||  ||.|..|.         .:| :......|..:...|.
Human   196 -------------DTSD--GSCTELPF---------KQP-NYYYKLRNFYSKQYHK--------- 226

  Fly   355 NRSSSGDGGKGSLSSGNDEEIGDGLASHHAAPQFIMSPAENKMFHAAAFNFPNIDPSALLGLNTQ 419
                                        |||     .|::.::          ::.......:|.
Human   227 ----------------------------HAA-----GPSQERV----------VEQPFAFSTSTD 248

  Fly   420 LQ--QSGDLAVSPQGGSTGSLLSGVIVPGGSGGTPSNSSSNNNNNNSNNQQ--QKVEQQSSPH-- 478
            |.  :|...|||   .|...|.|...:|......|.|.|:.:..:::..||  :::..:.:.|
Human   249 LTTVESQPCAVS---HSECILESPEHLPSNFLAQPVNDSAPHPESDATCQQPVKQMRLKKAIHLK 310

  Fly   479 --QLLQQQHHSTPHTNSPQLKQEQPKSGGGSCKSSDLHIAAGSERSLSRSSQGMPDAGGHSATPS 541
              ..|:.|.::.        :..:|||..|..|    .:.:.|:.:|.::|             |
Human   311 KLNFLKSQKYAE--------QVSEPKSDDGLTK----RLESASKNTLEKAS-------------S 350

  Fly   542 PTAAYHKRER-----------ERERERERERERERERSLDHERD--LERPGGTGSPPPPPPSH-H 592
            .:|...:.|.           |.||..:.....::.::|..:|.  .|..|.....|.....| .
Human   351 QSAEEKESEEVVSCENFNCISETERPEDPAALEDQSQTLQSQRQYACELCGKPFKHPSNLELHKR 415

  Fly   593 SHFGQHPLSLLPSHHQLHATHHELSAAAAHHAHAHAHAAHAHALAR-------AGSPMEHHHLLH 650
            ||.|:.|.       :.:......|.|.....|...|:.....:..       |...::.|.::|
Human   416 SHTGEKPF-------ECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIH 473

  Fly   651 HRRASLSPSGAVSSASGAGGRGGGAGGPGGPGGSLLSSVRA-QDVAQANRLLLPLPLNACHRCDV 714
                    ||.........||          |.|..|:::. :....|:::.         .||.
Human   474 --------SGEKPHLCDICGR----------GFSNFSNLKEHKKTHTADKVF---------TCDE 511

  Fly   715 CGKLLSTKLTLKRHKEQQHL--QPLNNAVCNLCHKVFRTLNSLNNH------------------- 758
            |||..:.:..|.:|: .:|.  :|.:   |:.|.|.|.....|..|
Human   512 CGKSFNMQRKLVKHR-IRHTGERPYS---CSACGKCFGGSGDLRRHVRTHTGEKPYTCEICNKCF 572

  Fly   759 -KSIYHRRQKNHHSYFHHGAGVSQAGSPGSRLHQSLS----------SLSAAAAAANNSVNVGGG 812
             :|...||.|..|         .:||.....:.:.||          |.|:.:.:.:.||.:...
Human   573 TRSAVLRRHKKMH---------CKAGDESPDVLEELSQAIETSDLEKSQSSDSFSQDTSVTLMPV 628

  Fly   813 SVGGAGGNAVAAAAAAAAAAAELLLSPIVGAAAV----AGGT---ASSTLQLAAAHQQQQQQSSP 870
            ||                   :|.:.|:..:.|.    :||:   ..|.:|......|::....|
Human   629 SV-------------------KLPVHPVENSVAEFDSHSGGSYCKLRSMIQPHGVSDQEKLSLDP 674

  Fly   871 G-IVKPCMDFLXDQQQLLQQLFHVALNNSAAA--------AAAAAAAAAAGGSGGGPGGVGAGPE 926
            | :.||.|     ||...|...:..::..|..        |...::.||....||.|.|..|...
Human   675 GKLAKPQM-----QQTQPQAYAYSDVDTPAGGEPLQADGMAMIRSSLAALDNHGGDPLGSRASST 734

  Fly   927 SI-NGGGQEYGGV 938
            :. |..||.:..:
Human   735 TYRNSEGQFFSSM 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
br	NP_001162638.2	BTB	22..118	CDD:279045	28/85 (33%)
		BTB	33..118	CDD:197585	28/85 (33%)
		C2H2 Zn finger	712..729	CDD:275368	6/16 (38%)
		C2H2 Zn finger	742..763	CDD:275368	7/40 (18%)
ZBTB49	NP_001317554.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..203		16/105 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	275..294		3/18 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910