Protein Alignment br and LOC1277065

DIOPT Version :10

• Sequence 1: NP_001162638.2
• Gene: br / 44505
• FlyBaseID: FBgn0283451
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: XP_061506393.1
• Gene: LOC1277065 / 1277065
• VectorBaseID: AGAMI1_001094
• Length: 892
• Species: Anopheles gambiae
• Alignment Length: 1142
• Identity: 250/1142 - (21%)
• Similarity: 364/1142 - (31%)
• Gaps: 420/1142 - (36%)

  Fly     1 MDDTQHFCLRWNNYQSSITSAFENLRDDEAFVDVTLACEGRSIKAHRVVLSACSPYFRELLKSTP 65
            |...|.:||||||:|.:..|.|..|..:|:.||||||.|||.::||:|||||||.||:.|..:.|
Mosquito     1 MMSVQQYCLRWNNHQPNFISVFSTLLHNESLVDVTLAAEGRQLQAHKVVLSACSSYFQSLFTANP 65

  Fly    66 CKHPVILLQDVNFMDLHALVEFIYHGEVNVHQKSLQSFLKTAEVLRVSGL--------------- 115
            |:||:::|:||.:.||..:|:|:|:|||||..:.|...|||||:|::.||
Mosquito    66 CQHPIVILKDVQYNDLKTMVDFMYYGEVNVSTEQLPQVLKTAEMLKIKGLAEMPDASAVCKADLS 130

  Fly   116 ---------------------------TQQQAEDTHSHLAQIQNLANSGGRTPLN---THTQSLP 150
                                       :||||:.......|.|.......:....   .|.|...
Mosquito   131 KLDPSELIQAANVIPGAAGDAIWGSAESQQQAQQQQQQQQQQQQQQQQQQQQQQQQQAQHQQQYQ 195

  Fly   151 H-------PHHGSLHDDGGSSTLFSRQGAGSPPPTAVPSLPSHINNQLLKRMAMMHRSSAAAAAE 208
            |       .....||..       ::|...||.||.        |.....|...:.::|..:.
Mosquito   196 HQQQQQQQQQQQQLHQQ-------TQQLRRSPSPTT--------NMSPAARRKRLRKTSTGSG-- 243

  Fly   209 ETSHAFKRLRGSDNSLPLSGAVGSGSNNNSPDLPPLHARSASPQQ----------------TPAD 257
              |.:.:||:........:.|....:...:..:....|.:|:.||                ..||
Mosquito   244 --SISSERLQQQQQQQAAAAAAAVAAQQQAAAVAAAAAAAAAAQQQAEEQQQQQQQQQQHGAGAD 306

  Fly   258 FSTIKHHNNNNTPPLKEEKRNGPTGNGNSGNGNG-----------NGNGASNGNGISISDKLGSL 311
            .|||     |..|.|..:::......|.:..|:|           ....|:.||.|.|
Mosquito   307 PSTI-----NLVPHLHIQQQVDNISYGTATTGHGALALGAAAAVAAAAAAAAGNNIRI------- 359

  Fly   312 TPSPLARAGADDVKSEPMDMVCSNNNANANDEHSNDSTGEHDANRSSSGDGGKGSLSSGNDEEIG 376
                        :|..|...|  :...:.:.:.|.|.||.|..:...:.|      .||..:.|.
Mosquito   360 ------------IKESPSSDV--DQQQHESSQESVDETGHHMPSIIKTED------LSGVAQTIP 404

  Fly   377 DGLA------------SHHAAPQFIMSPAENKMFHAAAFNFPNIDPSALLGLNTQLQQ------- 422
            ..::            |.|...|:.:.......|..|..       ...|||..|.||
Mosquito   405 MDISTTPTAVNITQSQSQHTGGQWTVIDTNYSRFGIAPI-------QTNLGLQQQQQQQQQQQQH 462

  Fly   423 -----------------------SGDLAVSPQGGSTGSLLSGVIVPGGSGGTPSNSSSNNNNN-- 462
                                   .||   |...||.|:..:.....|.:||....|:.:..||
Mosquito   463 QQQQVQQQHHQQTSQQQQQHQQHQGD---SQSLGSAGNGANNPANSGATGGGAGASAGSGGNNGG 524

  Fly   463 ----NSNNQQQKVEQQSSPHQLLQQQHHSTPHTNSPQLKQEQPKSGGGSCKSSDLHIAAGSERSL 523
                ::.|......|.::|.|:.|       |..|||:....|.|...|.:||:|
Mosquito   525 LAGASATNSNATTPQPTTPVQIYQ-------HPFSPQIISVNPNSMVNSYQSSNL---------- 572

  Fly   524 SRSSQGMPDAGGHSATPSPTAAYHKRERERERERERERERERERSLDHERDLERPGGTGSPPPPP 588
              |:...|.||.                            ::...|.:        .||:|
Mosquito   573 --STPTSPQAGS----------------------------DQTAGLVY--------STGTP---- 595

  Fly   589 PSHHSHFGQHPLSLLPSHHQLHATHHELSAAAAHHAHAHAHAAHAHALARAGSPMEHHHLLHHRR 653
                   .|.||.              .:.|.|...:|..:..:..|.|..|:
Mosquito   596 -------NQSPLG--------------TTTATASGTNASGNGGNGAAAAAGGN------------ 627

  Fly   654 ASLSPSGAVSSASGAGGRGGGAGGPGGPGGSLLSSVRAQDVAQANRLLLPLPLNACHRCDVCGKL 718
                 ..|..:.:|||..|.|||..||..|:..::|: |.|.:
Mosquito   628 -----GAAGGNGAGAGTAGSGAGAAGGAAGAAGATVQ-QPVKR---------------------- 664

  Fly   719 LSTKLTLKRHKEQQHLQPLNNAV----CNLCHKVFRTLNSLNNHKSIYHRRQKNHHSYFHHGAGV 779
               |.::....::..|:.| .||    ...| |..| |..:|| ::::...:|.
Mosquito   665 ---KRSVNPQGDENFLRAL-EAVRFGGIGFC-KAAR-LYGVNN-RTLWLEYKKR----------- 711

  Fly   780 SQAGSPGSR--------LHQSLSSLSAAAAAANNSVNVGGGSVGGAGGNAVAAAAAAAAAAAELL 836
               |.|.||        |..::|....|.....:.             ||.......|      |
Mosquito   712 ---GYPISRPSIKNRIKLEPNISPPPTATTPPGDE-------------NASLEHYDTA------L 754

  Fly   837 LSPIVGAA------------AVAGGTASSTLQLAAAHQQQQQQSSPGIVKPCMDFLXDQQQLLQQ 889
            .||.:..:            .......:...|:.||.||||||..            .||...||
Mosquito   755 SSPALNMSLQQQQQQQQQQQVQQQHQTNQQQQVTAAQQQQQQQQQ------------TQQHQQQQ 807

  Fly   890 LFHVALNNSAAAAAAAAAAAAAGGSGGGPGGVGAGPESINGGGQEYGGVQGPSGTPTVDLTQLEH 954
            .......|:||||||||..||:           :.|......|... ||.|...|..||
Mosquito   808 QQGTDTTNAAAAAAAAAVVAAS-----------STPLMCPPHGHTM-GVMGFLDTRHVD------ 854

  Fly   955 AAGGGGFSAAAALQHHLPHHLAHQHPMSHQ-HPHQLT 990
                  |:..|:|           |.||.| :|...|
Mosquito   855 ------FTTTASL-----------HQMSRQRYPDTAT 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
br	NP_001162638.2	BTB_POZ_BAB-like	31..114	CDD:349624	45/82 (55%)
		C2H2 Zn finger	712..729	CDD:275368	1/16 (6%)
		C2H2 Zn finger	742..763	CDD:275368	6/20 (30%)
LOC1277065	XP_061506393.1	None