Protein Alignment br and Btbd18

DIOPT Version :9

• Sequence 1: NP_001162638.2
• Gene: br / 44505
• FlyBaseID: FBgn0283451
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: XP_002729248.1
• Gene: Btbd18 / 100363270
• RGDID: 2323370
• Length: 724
• Species: Rattus norvegicus
• Alignment Length: 683
• Identity: 150/683 - (21%)
• Similarity: 224/683 - (32%)
• Gaps: 229/683 - (33%)

  Fly    21 AFENLRDDE---AFVDVTLACEGRSIKAHRVVLSACSPYFRELL-KSTPCKHPVILLQ--DVNFM 79
            ||..|...:   .|.|..|..||.::.||..:||||||:|.|.| :..|.:...::|:  .:...
  Rat    20 AFLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLELGGLKIQ 84

  Fly    80 DLHALVEFIYHGEVNVHQKSLQSFLKTAEVLRVSGLTQQQAED-----------THSHLAQIQNL 133
            .|..||:|:|..|:.|.|:..|..|..|..||||.|...|.|.           .:....|..:.
  Rat    85 TLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSELETLQLEGGKLVKAPQGRRLNRECLQPPSA 149

  Fly   134 A---------NSGGRTPL---------------------NTHTQS-LPHPHHGS----------- 156
            |         .|..||||                     ..|.:| ||:..:.|
  Rat   150 APISARVVVPRSRPRTPLPVTQTPSPLGAVKLKSLGEEEGAHKKSNLPNADNLSDTLLLKKKARV 214

  Fly   157 -LHDDGGSSTLFSRQG----AGSPPPTAVPSLPSHINNQLLKRMAMMHRSSAAAAAEETSHAFKR 216
             |..:..||....|:|    ..:|..||:|||...::.|||.|...:.||      :.:.|.:
  Rat   215 CLTQERSSSPSSQREGPKENKSNPGSTALPSLYPSVDEQLLPRKIRLSRS------KPSPHVY-- 271

  Fly   217 LRGSDNSLPLSGAVGSGSNNNSPDLPPLHARSAS------PQQTPADFSTIKHHNNNNTPPLKEE 275
                 .|.|.|...|..|...:|.......|:.|      .:|.|.:.||::     :||
  Rat   272 -----TSKPSSMLSGPSSMPTAPGRRLWRQRTVSEATQGVDKQKPGEVSTLQ-----STP----- 321

  Fly   276 KRNGPTGNGNSGNGNGNGNGASNGNGISISDKLGSLTPSPLARAGADDVKSEP----------MD 330
               .|...|.:|                     |...|||.:||.|.:...|.          ::
  Rat   322 ---DPPDVGKTG---------------------GKKQPSPESRAPASNSVEEGQVGRVKLRKIVN 362

  Fly   331 MVCSNNNANANDEHSNDSTGEHDANRSSSGDGGKGS-LSSGNDEEIGDGLASHHAAP-----QFI 389
            ..|..........::.||.   ....||..|...|: |||.|::||...:...|.:|     |.|
  Rat   363 GTCWEVVQEPPIRNTQDSP---QILESSDADEPPGTLLSSVNEQEIPARIQLCHDSPENSRLQDI 424

  Fly   390 MSPAENKMFHAAA----FNFP---------NID-------PSALL--------------GLNTQL 420
            :..|.:...|...    .:.|         |||       .:.||              ...::|
  Rat   425 LLSASHSPDHPVVKSEFGSSPMLTGKEPELNIDCREPYTFDTTLLSQPCEAEQYRITSAAATSEL 489

  Fly   421 QQSGDLA-----VSPQGGSTGSLLSGVIVPGGSG-GTPSNSSSNNNNN----------------- 462
            ::..|..     |.|..||..|       ||..| .|||...|....|
  Rat   490 EEILDFMLCGSDVEPPVGSLES-------PGAEGCRTPSYHLSETGKNWIEGEEWCLPDMELWPR 547

  Fly   463 -NSNNQQQKVEQQSSPHQ-----LLQQQHHSTPHTNSP----------------------QLKQE 499
             .:..:::.|.:...|.:     :::.::..:....||                      ::...
  Rat   548 DLTGLEKEPVGENKEPVEPFSPLVMRSENTESIEPLSPLVMPSEVSREELSLRGSWTPDLEITSS 612

  Fly   500 QPKSGGGSCKSSDLHIAAGSERSLSRSSQGMPD 532
            ||..|.|. |...|..:..|:||.|..|...|:
  Rat   613 QPLDGQGE-KLIHLDSSDPSQRSYSDLSPPCPN 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
br	NP_001162638.2	BTB	22..118	CDD:279045	36/101 (36%)
		BTB	33..118	CDD:197585	33/87 (38%)
		C2H2 Zn finger	712..729	CDD:275368
		C2H2 Zn finger	742..763	CDD:275368
Btbd18	XP_002729248.1	BTB	24..123	CDD:279045	35/98 (36%)
		BTB	35..123	CDD:197585	33/87 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10373
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910