DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Surf1 and sft-1

DIOPT Version :9

Sequence 1:	NP_524758.1	Gene:	Surf1 / 44498	FlyBaseID:	FBgn0029117	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_497657.1	Gene:	sft-1 / 175415	WormBaseID:	WBGene00004787	Length:	323	Species:	Caenorhabditis elegans

Alignment Length:	255	Identity:	98/255 - (38%)
Similarity:	139/255 - (54%)	Gaps:	15/255 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 KDKEKIAPLGW-----FLLLIPATTFGLGCWQVKRKIWKEQLIKDLNKQLSTAPVALPDDLT--D 112
            |.|:....:.|     .:|.||...|.||.||..|..||..||:.|..:|:.....||:||:  .
Worm    71 KSKKSKKSIKWSTGSVLMLTIPVFAFSLGIWQTFRLKWKLDLIEHLKGRLNQTAQELPEDLSCES 135

  Fly   113 LAQMEYRLVKIRGRFLHDKEMRLGPRSLIRPDGVETQ---GGLFSQRD-SGNGYLIVTPFQLADR 173
            |..:||..|.:.|.|||:||..:.||....| |.:|.   |.:.|:.: |.:|..::|||:|.:.
Worm   136 LEPLEYCRVTVTGEFLHEKEFIISPRGRFDP-GKKTSAAAGSMLSENEMSSHGGHLITPFRLKNS 199

  Fly   174 DDIVLVNRGWVSRKQVEPETRPLGQQQAEVELTAVVRKGEARPQFTPDH--KGNVYLYRDLARMC 236
            ..|:|:||||:.....:||||.....:..:.|.|:|||.|.||||...:  :..|:.||||.:|.
Worm   200 GKIILINRGWLPSFYFDPETRQKTNPRGTLTLPAIVRKTEKRPQFVGQNVPEQGVWYYRDLNQMA 264

  Fly   237 AATGAAPVFLDAVYDPQTAAHAPIGGQTRVTLRNDHLSYLVTWFSLSAATSFLWYRQIVK 296
            ...|..||.|||.|: .|....||||||.:.:||:||:||.|||:|:..|..:|..:..|
Worm   265 KHYGTEPVLLDAAYE-TTVPGGPIGGQTNINVRNEHLNYLTTWFTLTLVTMLMWIHKFRK 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Surf1	NP_524758.1	SURF1	74..289	CDD:119401	90/222 (41%)
sft-1	NP_497657.1	SURF1	96..316	CDD:119401	90/221 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156777
Domainoid	1	1.000	159	1.000	Domainoid score	I2494
eggNOG	1	0.900	-	-		E1_COG3346
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2387
Inparanoid	1	1.050	168	1.000	Inparanoid score	I2776
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55729
OrthoDB	1	1.010	-	-		D491252at33208
OrthoFinder	1	1.000	-	-		FOG0003659
OrthoInspector	1	1.000	-	-		oto18807
orthoMCL	1	0.900	-	-		OOG6_103106
Panther	1	1.100	-	-	LDO	PTHR23427
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1335
SonicParanoid	1	1.000	-	-		X4077
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800