Protein Alignment Tollo and AT5G46270

DIOPT Version :10

• Sequence 1: NP_524757.1
• Gene: Tollo / 44497
• FlyBaseID: FBgn0029114
• Length: 1346
• Species: Drosophila melanogaster
• Sequence 2: NP_001330138.1
• Gene: AT5G46270 / 834669
• AraportID: AT5G46270
• Length: 1145
• Species: Arabidopsis thaliana
• Alignment Length: 882
• Identity: 166/882 - (18%)
• Similarity: 299/882 - (33%)
• Gaps: 270/882 - (30%)

  Fly    26 KTVLYQAPDECRWSGGGEHDITLVCHLRTINSELENTNFSVIQPQNTVRLRLECNDALFFQSSLS 90
            :.:|.....:.:|.|.|...|.:..:...:.:...:..:.|..|.....|.:.|..|  |:....
plant   315 QVILDSLVGQTQWFGSGSRIIAVTNNKHFLRAHEIDHIYEVSLPTQQHALAMLCQSA--FRKKSP 377

  Fly    91 PDSFRSLVELRDLTIEYCKLGNLTDGSFRGLQELRNLTIRTHNGD-WSTMSLEMASNSFVEFRQL 154
            |:.|..||......::...||....||:          :|..:.: |..|              |
plant   378 PEGFEMLVVQVARHVDSLPLGLNVLGSY----------LRGRDKEYWMEM--------------L 418

  Fly   155 ERLDLSLNNIWLIPDGMVCPLKSLQHLNASYNKIQDISNFYFSASLSSRKARVCGSTLQSLDLSA 219
            .||:                       |..::||:.|....:. .|.|.:.:   :..:.:....
plant   419 PRLE-----------------------NGLHDKIEKILRISYD-GLGSEEDK---AIFRHIACLF 456

  Fly   220 NKM-VSLPTAMLSALGRLTHLNMA-KNSMSFLADRAFEGLLSLRVVDLSANRLTSLPPELFAETK 282
            |.| |:..|::|:.||    :|:. ||    |.|::   ::.:|...:..:|:..........|:
plant   457 NHMEVTTITSLLTDLG----INIGLKN----LVDKS---IIHVRRGCVEMHRMLQEMGRKIVRTQ 510

  Fly   283 QL-----QEIYLRNNSI-NVLAPGIFGELAELLVLDLASNELNSQWINAATFVGLKRLMMLDLSA 341
            .:     :|..:..|.| :||:.||..:  ::|.:.|.:.|::..:::.:.|.|:..|..|::.:
plant   511 SIDKPGKREFLVDPNDISDVLSEGIGTQ--KVLGISLNTGEIDELYVHESAFKGMSNLRFLEIDS 573

  Fly   342 NKISRLEAHIFRPLASLQILKLEDNYIDQLPGGIFADLTNLHTLILSRNRISVIEQRTLQGLKNL 406
            ....: ...::.|           ..:|.||..:        .|:...|    ...|.:.
plant   574 KNFGK-AGRLYLP-----------ESLDYLPPRL--------KLLCWPN----FPMRCMP----- 609

  Fly   407 LVLSLDFNRISRMDQRSLVNCSQLQDLHLNDNKLQAVPEALAHVQLLKTLD-VGENMISQIENTS 470
                      |.....:||.      |.:.::||..:.|.:|.:..||.:| ||.:.:.:|.:.|
plant   610 ----------SNFRPENLVT------LKMPNSKLHKLWEGVASLTCLKEMDMVGSSNLKEIPDLS 658

  Fly   471 I-TQLE--------SLYGLRMTENSLTHIRRGVFDRMSSLQILNLSQNKLKSIEAGSLQRNSQLQ 526
            : |.||        ||..|..:..:|..:.:...:...||:||....| |||::..:.:..|:|:
plant   659 MPTNLEILKLGFCKSLVELPSSIRNLNKLLKLDMEFCHSLEILPTGFN-LKSLDHLNFRYCSELR 722

  Fly   527 AIRLDGNQLKSIAGLFTEL-PNLVWLNISGNRLEKFDYSHIPIGLQWLDVRANRITQLGNYFEIE 590
            .              |.|. .|:..|.:.|..:|:|                   ..|.|..
plant   723 T--------------FPEFSTNISVLMLFGTNIEEF-------------------PNLENLV--- 751

  Fly   591 SELSLSTFDASYNLLTEITASSIPNSVEVLYLNDNQISKIQPYTFFKKPNLTRVDLVRNRLTTLE 655
             |||||..::                      :..|...::|.|.|              |..|.
plant   752 -ELSLSKEES----------------------DGKQWDGVKPLTPF--------------LEMLS 779

  Fly   656 P--NALRLSPIAEDREIPEFYIGHNAYECDCNLDWLQKVNRESRTQPQLMDLDQIHCRLAYARGS 718
            |  .:|:|..|....|:|..:               |.:|       ||.:|...:||......:
plant   780 PTLKSLKLENIPSLVELPSSF---------------QNLN-------QLKELSITYCRNLETLPT 822

  Fly   719 SHVSLIEAKSDDFLCKYASHCFALCHCCDFQACDCKMECPDRCSCYHDQSWTSNVVDCSRASYEQ 783
            .    |..||.::||              |:.|......|:         .::|:   |..:.|:
plant   823 G----INLKSLNYLC--------------FKGCSQLRSFPE---------ISTNI---SVLNLEE 857

  Fly   784 TLPSHIPMDSTQLYLDGNNFRELQSHAFIGRKRLKVLHLNHSRIEVLHNRTFYGLLELEVLQLQS 848
            |....:|...       .||..|.........:||.|.||..:::.|.:..|.....|.|:.|..
plant   858 TGIEEVPWQI-------ENFFNLTKLTMRSCSKLKCLSLNIPKMKTLWDVDFSDCAALTVVNLSG 915

  Fly   849 NQLKALNGNEFQGLDNLQELYLQHNAIATIDTLTFTH 885
            .....|:..|...||.    :|......::|..|..|
plant   916 YPSDTLSEEEDDSLDP----FLDFRGCFSLDPETVLH 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tollo	NP_524757.1	LRR	54..400	CDD:443914	62/354 (18%)
		leucine-rich repeat	100..123	CDD:275380	4/22 (18%)
		leucine-rich repeat	124..144	CDD:275380	3/20 (15%)
		leucine-rich repeat	154..177	CDD:275380	3/22 (14%)
		leucine-rich repeat	178..201	CDD:275380	4/22 (18%)
		leucine-rich repeat	212..235	CDD:275380	6/23 (26%)
		leucine-rich repeat	236..259	CDD:275380	5/23 (22%)
		LRR	239..634	CDD:443914	77/412 (19%)
		leucine-rich repeat	260..283	CDD:275380	3/22 (14%)
		leucine-rich repeat	284..307	CDD:275380	7/28 (25%)
		leucine-rich repeat	308..333	CDD:275380	5/24 (21%)
		leucine-rich repeat	334..357	CDD:275380	3/22 (14%)
		leucine-rich repeat	358..381	CDD:275380	3/22 (14%)
		leucine-rich repeat	382..405	CDD:275380	3/22 (14%)
		leucine-rich repeat	406..429	CDD:275380	3/22 (14%)
		leucine-rich repeat	430..452	CDD:275380	5/21 (24%)
		leucine-rich repeat	453..500	CDD:275380	14/56 (25%)
		leucine-rich repeat	501..521	CDD:275380	7/19 (37%)
		leucine-rich repeat	525..547	CDD:275380	3/22 (14%)
		leucine-rich repeat	548..573	CDD:275380	4/24 (17%)
		leucine-rich repeat	604..640	CDD:275380	4/35 (11%)
		LRR_8	616..>660	CDD:404697	7/45 (16%)
		leucine-rich repeat	641..688	CDD:275380	8/48 (17%)
		leucine-rich repeat	689..816	CDD:275380	23/126 (18%)
		LRR	<794..>920	CDD:443914	21/92 (23%)
		leucine-rich repeat	817..864	CDD:275380	13/46 (28%)
		leucine-rich repeat	865..888	CDD:275380	4/21 (19%)
		leucine-rich repeat	889..910	CDD:275380
		TIR	1076..1211	CDD:214587
AT5G46270	NP_001330138.1	PLN03210	12..1138	CDD:215633	166/882 (19%)
		leucine-rich repeat	617..639	CDD:275380	7/27 (26%)
		leucine-rich repeat	640..656	CDD:275380	6/15 (40%)
		leucine-rich repeat	663..686	CDD:275380	6/22 (27%)
		leucine-rich repeat	687..709	CDD:275380	6/22 (27%)
		leucine-rich repeat	710..730	CDD:275380	4/33 (12%)
		leucine-rich repeat	750..781	CDD:275380	11/70 (16%)
		leucine-rich repeat	782..805	CDD:275380	7/44 (16%)
		leucine-rich repeat	806..828	CDD:275380	5/25 (20%)
		leucine-rich repeat	840..875	CDD:275378	9/53 (17%)
		leucine-rich repeat	876..907	CDD:275378	7/30 (23%)