DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tollo and AT5G05400

DIOPT Version :9

Sequence 1:	NP_524757.1	Gene:	Tollo / 44497	FlyBaseID:	FBgn0029114	Length:	1346	Species:	Drosophila melanogaster
Sequence 2:	NP_196159.1	Gene:	AT5G05400 / 830422	AraportID:	AT5G05400	Length:	874	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	121/557 - (21%)
Similarity:	206/557 - (36%)	Gaps:	161/557 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 GSFRGLQELRNLTIRTHNGD----WSTMSLEMASNSFVEFRQLERLDLSLNNIWLIPDGMVCPLK 176
            |.|.|: |...|:|...:.|    ..|.|..:.|..|.|..::.:.||.  ..| :..|::...|
plant   373 GVFSGI-EADILSILKFSYDDLKCEKTKSCFLFSALFPEDYEIGKDDLI--EYW-VGQGIILGSK 433

  Fly   177 SLQHLNASYNKIQDISNFY-FSASLSSRKARV--------------CGSTLQSLDLSANKMVSLP 226
            .:.:  ..|..|..::..| ...|.:..|.::              ||...|.     |.:|...
plant   434 GINY--KGYTIIGTLTRAYLLKESETKEKVKMHDVVREMALWISSGCGDQKQK-----NVLVVEA 491

  Fly   227 TAMLSALGRLTHLNMAKNSMSFLADRAFEGLLSLRVVDLSANRLTSLPPELFAETKQLQEIYLRN 291
            .|.|..:.::.. ..|...||.:.::..|...||                   ...:|:.:.||:
plant   492 NAQLRDIPKIED-QKAVRRMSLIYNQIEEACESL-------------------HCPKLETLLLRD 536

  Fly   292 NSINVLAPGIFGELAELLVLDLASNELNSQWINAATFVGLKRLMMLDLSANKISRLEAHIFRPLA 356
            |.:..::......:..|:||||:   ||...|...:|..|..|..|:||...|:.|...:: .|.
plant   537 NRLRKISREFLSHVPILMVLDLS---LNPNLIELPSFSPLYSLRFLNLSCTGITSLPDGLY-ALR 597

  Fly   357 SLQILKLEDNYIDQLPGGIFADLTNLHTLILSRNRISVIEQ--RTLQGLKNLLVLSLDFNRISRM 419
            :|..|.||..|:.:....|. ||.||..|.|..:.|.:.::  |.:|.:|:|.:|::
plant   598 NLLYLNLEHTYMLKRIYEIH-DLPNLEVLKLYASGIDITDKLVRQIQAMKHLYLLTI-------- 653

  Fly   420 DQRSLVNCSQLQDLHLNDNKLQAVPEAL-----AHVQLLKT----------LDVGENMISQIENT 469
               :|.|.|.| ::.|.|.:..:..|.|     ::.|.||.          |::.::.|.:||..
plant   654 ---TLRNSSGL-EIFLGDTRFSSYTEGLTLDEQSYYQSLKVPLATISSSRFLEIQDSHIPKIEIE 714

  Fly   470 SITQLES-LYGLRMTEN-SLTHIRRGVFDRMSSLQ------------------------ILNLSQ 508
            ..:..|| :.|.|:..: |..::|:...|..:.|:                        |::.|:
plant   715 GSSSNESEIVGPRVRRDISFINLRKVRLDNCTGLKDLTWLVFAPHLATLYVVCLPDIEHIISRSE 779

  Fly   509 NK-------------LKSIEAGSLQRNSQLQAIRLDG---NQLKSI----AGLFTELP------- 546
            ..             .:.:|..:|:...||::|..|.   .:||.|    ....|:||
plant   780 ESRLQKTCELAGVIPFRELEFLTLRNLGQLKSIYRDPLLFGKLKEINIKSCPKLTKLPLDSRSAW 844

  Fly   547 --NLV------WLNISGNRLEKFDYSHIPIGLQWLDV 575
              |:|      ||.                ||||.||
plant   845 KQNVVINAEEEWLQ----------------GLQWEDV 865

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tollo	NP_524757.1	LRR_RI	<85..281	CDD:238064	35/183 (19%)
		leucine-rich repeat	100..123	CDD:275380	3/6 (50%)
		leucine-rich repeat	124..144	CDD:275380	5/23 (22%)
		LRR_8	152..222	CDD:290566	14/84 (17%)
		leucine-rich repeat	154..177	CDD:275380	4/22 (18%)
		leucine-rich repeat	178..201	CDD:275380	4/23 (17%)
		LRR	210..656	CDD:227223	97/444 (22%)
		leucine-rich repeat	212..235	CDD:275380	5/22 (23%)
		leucine-rich repeat	236..259	CDD:275380	4/22 (18%)
		leucine-rich repeat	260..283	CDD:275380	1/22 (5%)
		LRR_RI	276..558	CDD:238064	80/359 (22%)
		leucine-rich repeat	284..307	CDD:275380	4/22 (18%)
		leucine-rich repeat	308..333	CDD:275380	10/24 (42%)
		leucine-rich repeat	334..357	CDD:275380	7/22 (32%)
		leucine-rich repeat	358..381	CDD:275380	8/22 (36%)
		leucine-rich repeat	382..405	CDD:275380	6/24 (25%)
		leucine-rich repeat	406..429	CDD:275380	4/22 (18%)
		leucine-rich repeat	430..452	CDD:275380	5/26 (19%)
		leucine-rich repeat	453..500	CDD:275380	13/58 (22%)
		leucine-rich repeat	501..521	CDD:275380	5/56 (9%)
		leucine-rich repeat	525..547	CDD:275380	9/37 (24%)
		leucine-rich repeat	548..573	CDD:275380	6/30 (20%)
		leucine-rich repeat	604..640	CDD:275380
		leucine-rich repeat	641..688	CDD:275380
		leucine-rich repeat	689..816	CDD:275380
		LRR_8	815..875	CDD:290566
		leucine-rich repeat	817..864	CDD:275380
		LRR_8	864..921	CDD:290566
		leucine-rich repeat	865..888	CDD:275380
		leucine-rich repeat	889..910	CDD:275380
		TIR	1076..1211	CDD:214587
AT5G05400	NP_196159.1	NB-ARC	159..429	CDD:279299	16/59 (27%)
		leucine-rich repeat	507..528	CDD:275378	5/39 (13%)
		LRR_8	527..582	CDD:290566	16/57 (28%)
		leucine-rich repeat	529..552	CDD:275378	4/22 (18%)
		leucine-rich repeat	553..575	CDD:275378	10/24 (42%)
		LRR_8	575..627	CDD:290566	18/53 (34%)
		leucine-rich repeat	576..598	CDD:275378	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010