DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tollo and AT4G09420

DIOPT Version :9

Sequence 1:	NP_524757.1	Gene:	Tollo / 44497	FlyBaseID:	FBgn0029114	Length:	1346	Species:	Drosophila melanogaster
Sequence 2:	NP_192680.1	Gene:	AT4G09420 / 826524	AraportID:	AT4G09420	Length:	457	Species:	Arabidopsis thaliana

Alignment Length:	351	Identity:	58/351 - (16%)
Similarity:	119/351 - (33%)	Gaps:	132/351 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 TKQLQEIYL-RNNSINVLAPGIFGELAELLVLDLASNELNSQWINAAT-----FVGLKRLM---- 335
            |.|:::|.| ::..||:.|              ..|:.::::.||:.|     .:||.|.|
plant   165 TSQVKQILLDKDKQINLKA--------------TISHTVSNKQINSLTTKNVGLIGLDRHMLALN 215

  Fly   336 -MLDLSANKISR--------------LEAHIFRPLASLQILKLEDNYIDQLPGGIFADLTNLHTL 385
             :|||.:|:..|              |..:::..|                       ..|.|..
plant   216 ELLDLKSNEEVRLIGICGQGGVGKTTLARYVYEEL-----------------------FKNFHAH 257

  Fly   386 ILSRNRISVIEQRTLQGLKNLLVLSLDFNRISRMDQRSLVNCSQLQDLHLNDNKLQAVPEALAHV 450
            :...|...:.:|.|.:......:.|.:....::...|:|...|..            :...::|.
plant   258 VFVDNAGKIYKQDTDESHSQKSLTSKEIQEGTQTVTRTLTVASDF------------IKSTVSHQ 310

  Fly   451 QLLKTLDVGENMISQIENTSITQLESLYGLRMTENSLTHIRRGVFDRMSSLQILNLSQNKLKSIE 515
            :.|..:|..:| |.|:|     ::.::.||....:                :::.::|:| |.::
plant   311 RSLLVVDCVDN-IKQLE-----EIANIVGLCFPGS----------------RVILVTQDK-KLLD 352

  Fly   516 AGSLQRNSQLQAIRLDGNQLKSIAGLFTELPNLVWLNISGNRLEKFDYSHIPIGLQWLDVRANRI 580
            ...::...::|::|.|     ....:|::              ..|:..|.|...:.|..||.|:
plant   353 DFGVEHVYEVQSLRYD-----EALQVFSQ--------------SAFNQQHPPASFESLSFRAVRV 398

  Fly   581 TQL----------------GNYFEIE 590
            ...                |.|:|.|
plant   399 AGFLPLLLKILGSSLQDKDGKYWEKE 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tollo	NP_524757.1	LRR_RI	<85..281	CDD:238064	58/351 (17%)
		leucine-rich repeat	100..123	CDD:275380
		leucine-rich repeat	124..144	CDD:275380
		LRR_8	152..222	CDD:290566
		leucine-rich repeat	154..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		LRR	210..656	CDD:227223	58/351 (17%)
		leucine-rich repeat	212..235	CDD:275380
		leucine-rich repeat	236..259	CDD:275380
		leucine-rich repeat	260..283	CDD:275380	1/1 (100%)
		LRR_RI	276..558	CDD:238064	47/301 (16%)
		leucine-rich repeat	284..307	CDD:275380	5/23 (22%)
		leucine-rich repeat	308..333	CDD:275380	6/29 (21%)
		leucine-rich repeat	334..357	CDD:275380	8/41 (20%)
		leucine-rich repeat	358..381	CDD:275380	0/22 (0%)
		leucine-rich repeat	382..405	CDD:275380	4/22 (18%)
		leucine-rich repeat	406..429	CDD:275380	3/22 (14%)
		leucine-rich repeat	430..452	CDD:275380	1/21 (5%)
		leucine-rich repeat	453..500	CDD:275380	8/46 (17%)
		leucine-rich repeat	501..521	CDD:275380	3/19 (16%)
		leucine-rich repeat	525..547	CDD:275380	4/21 (19%)
		leucine-rich repeat	548..573	CDD:275380	3/24 (13%)
		leucine-rich repeat	604..640	CDD:275380
		leucine-rich repeat	641..688	CDD:275380
		leucine-rich repeat	689..816	CDD:275380
		LRR_8	815..875	CDD:290566
		leucine-rich repeat	817..864	CDD:275380
		LRR_8	864..921	CDD:290566
		leucine-rich repeat	865..888	CDD:275380
		leucine-rich repeat	889..910	CDD:275380
		TIR	1076..1211	CDD:214587
AT4G09420	NP_192680.1	TIR	12..151	CDD:279864
AT4G09420	NP_192680.1	P-loop_NTPase	212..>334	CDD:304359	23/162 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	44	1.000	Domainoid score	I4673
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010