DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tollo and RLP35

DIOPT Version :9

Sequence 1:NP_524757.1 Gene:Tollo / 44497 FlyBaseID:FBgn0029114 Length:1346 Species:Drosophila melanogaster
Sequence 2:NP_001319521.1 Gene:RLP35 / 820279 AraportID:AT3G11080 Length:943 Species:Arabidopsis thaliana


Alignment Length:938 Identity:209/938 - (22%)
Similarity:335/938 - (35%) Gaps:265/938 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 PDSFRSLVELRD-------LTIEYCKLGNL------TDGSFRGLQELRN---LTIRTHNGDWSTM 139
            |:...:|:||::       .:.:||...|.      |..|:|...:..|   :|..|.:|:...:
plant    40 PEQRDALLELKNEFEIGKPSSNDYCYRNNSRVSPHPTTESWRNNSDCCNWEGITCDTKSGEVIEL 104

  Fly   140 SLEM--------ASNSFVEFRQLERLDLSLNNIWLIPDGMV-CPLKSLQHLNA---SYNKI---- 188
            .|..        :::|....:.|..|||:.|::    ||.: ..:.:|.||.:   |||:.    
plant   105 DLSCSWLYGSFHSNSSLFRLQNLRVLDLTQNDL----DGEIPSSIGNLSHLTSLHLSYNQFLGLI 165

  Fly   189 -QDISNFYFSASLSSRKARVCGSTLQSLDLSANKMVSLPTAMLSALGRLTHLNMAKNSMSFLADR 252
             ..|.|.               |.|.||.||:|:......:.:..|..||.|.::.|..|.....
plant   166 PSSIENL---------------SRLTSLHLSSNQFSGQIPSSIGNLSHLTSLELSSNQFSGQIPS 215

  Fly   253 AFEGLLSLRVVDLSANRLTSLPPELFAETKQLQEIYLRNNSINVLAPGIFGELAELLVLDLASNE 317
            :...|.:|..:.|.:|......|.......:|..:||..|:.....|..||.|.:|:||.:.||:
plant   216 SIGNLSNLTFLSLPSNDFFGQIPSSIGNLARLTYLYLSYNNFVGEIPSSFGNLNQLIVLQVDSNK 280

  Fly   318 LNSQWINAATFVGLKRLMMLDLSANKISRLEAHIFRPLASLQILKLEDN-YIDQLPGGIF----- 376
            |:..  ...:.:.|.||..|.||.|:.:....:....|::|...:..:| :...||..:|     
plant   281 LSGN--VPISLLNLTRLSALLLSHNQFTGTIPNNISLLSNLMDFEASNNAFTGTLPSSLFNIPPL 343

  Fly   377 --ADL-----------------TNLHTLILSRNRISVIEQRTLQGLKNLLVLSL----------D 412
              .||                 :||..||:..|.......|:|....||.:..|          |
plant   344 IRLDLSDNQLNGTLHFGNISSPSNLQYLIIGSNNFIGTIPRSLSRFVNLTLFDLSHLNTQCRPVD 408

  Fly   413 FNRISRMDQRSLVNCSQL--QDLHLNDNKLQAVPEALAHVQLLKTLDVGENMISQIENTSIT--- 472
            |:..|.:.....:..|.|  ..:.|||        .|.:.:.|::||:..|::|....:|::   
plant   409 FSIFSHLKSLDDLRLSYLTTTTIDLND--------ILPYFKTLRSLDISGNLVSATNKSSVSSDP 465

  Fly   473 ---QLESLY--GLRMTENSLTHIRRGVFDRMSSLQILNLSQNKLKSIEAGSLQRNSQLQAIRLDG 532
               .::|||  |..:|:  ...|.|    ....|..|::|.||:|.                   
plant   466 PSQSIQSLYLSGCGITD--FPEILR----TQHELGFLDVSNNKIKG------------------- 505

  Fly   533 NQLKSIAGLFTELPNLVWLNISGNRLEKFDYSHIPIGLQWLDVRANRITQL---GNYF--EIESE 592
                .:.|....||||.:||:|.|....|:.|....||.  .||...:..|   .|.|  :|.|.
plant   506 ----QVPGWLWTLPNLFYLNLSNNTFISFESSSKKHGLS--SVRKPSMIHLFASNNNFTGKIPSF 564

  Fly   593 L----SLSTFDAS---YNLLTEITASSIPNSVE-------VLYLNDNQISKIQPYTFFKKPNLTR 643
            :    ||:|.|.|   ||       .|||..:|       ||.|..|.:|...|...|:  :|..
plant   565 ICGLRSLNTLDLSENNYN-------GSIPRCMEKLKSTLFVLNLRQNNLSGGLPKHIFE--SLRS 620

  Fly   644 VDLVRNRLTTLEPNAL-RLSPIAEDREIPEFYIGHNAYECDCNLDWLQ-KVNRESRTQP-QLMDL 705
            :|:..|.|....|.:| |.|                      ||:.|. :.||.:.|.| .|..|
plant   621 LDVGHNLLVGKLPRSLIRFS----------------------NLEVLNVESNRINDTFPFWLSSL 663

  Fly   706 DQIHCRLAYARGSSHVSLIEAKSDDFLCKYASHCFALCHCCDFQACDCKMECPDRCSCYHDQSWT 770
            .::.. |.....:.|..:.||...:.                                       
plant   664 SKLQV-LVLRSNAFHGPIHEATFPEL--------------------------------------- 688

  Fly   771 SNVVDCSRASYEQTLPSHI-----PMDSTQLYLDGNNFRELQSHAFIGRKRLKVLHLNHSRIEVL 830
             .::|.|...:..|||:..     .|.|.....|.:|.:.:.|..:.  :...||......:|::
plant   689 -RIIDISHNHFNGTLPTEYFVKWSAMSSLGKNEDQSNEKYMGSGLYY--QDSMVLMNKGLAMELV 750

  Fly   831 HNRTFYGLLELEVLQLQSNQLKALNGNEFQG--------LDNLQELYLQHNAIATIDTLTFTHLY 887
            ...|.|..|:             .:||:|:|        |..|..|.|.:||.......:..:|.
plant   751 RILTIYTALD-------------FSGNKFEGEIPKSIGLLKELLVLNLSNNAFGGHIPSSMGNLT 802

  Fly   888 HLKILRLDHNAITSFAVWNFLPSYLNEL 915
            .|:.|.:..|.:|     ..:|..|.:|
plant   803 ALESLDVSQNKLT-----GEIPQELGDL 825

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TolloNP_524757.1 LRR_RI <85..281 CDD:238064 49/222 (22%)
leucine-rich repeat 100..123 CDD:275380 7/35 (20%)
leucine-rich repeat 124..144 CDD:275380 5/30 (17%)
LRR_8 152..222 CDD:290566 22/78 (28%)
leucine-rich repeat 154..177 CDD:275380 7/23 (30%)
leucine-rich repeat 178..201 CDD:275380 8/30 (27%)
LRR 210..656 CDD:227223 127/509 (25%)
leucine-rich repeat 212..235 CDD:275380 7/22 (32%)
leucine-rich repeat 236..259 CDD:275380 6/22 (27%)
leucine-rich repeat 260..283 CDD:275380 4/22 (18%)
LRR_RI 276..558 CDD:238064 76/326 (23%)
leucine-rich repeat 284..307 CDD:275380 8/22 (36%)
leucine-rich repeat 308..333 CDD:275380 7/24 (29%)
leucine-rich repeat 334..357 CDD:275380 6/22 (27%)
leucine-rich repeat 358..381 CDD:275380 7/47 (15%)
leucine-rich repeat 382..405 CDD:275380 6/22 (27%)
leucine-rich repeat 406..429 CDD:275380 5/32 (16%)
leucine-rich repeat 430..452 CDD:275380 5/23 (22%)
leucine-rich repeat 453..500 CDD:275380 13/54 (24%)
leucine-rich repeat 501..521 CDD:275380 6/19 (32%)
leucine-rich repeat 525..547 CDD:275380 2/21 (10%)
leucine-rich repeat 548..573 CDD:275380 9/24 (38%)
leucine-rich repeat 604..640 CDD:275380 11/42 (26%)
leucine-rich repeat 641..688 CDD:275380 10/47 (21%)
leucine-rich repeat 689..816 CDD:275380 21/133 (16%)
LRR_8 815..875 CDD:290566 15/67 (22%)
leucine-rich repeat 817..864 CDD:275380 11/54 (20%)
LRR_8 864..921 CDD:290566 13/52 (25%)
leucine-rich repeat 865..888 CDD:275380 6/22 (27%)
leucine-rich repeat 889..910 CDD:275380 4/20 (20%)
TIR 1076..1211 CDD:214587
RLP35NP_001319521.1 LRRNT_2 39..95 CDD:311940 12/54 (22%)
PLN00113 79..>658 CDD:331614 160/669 (24%)
leucine-rich repeat 103..123 CDD:275380 2/19 (11%)
leucine-rich repeat 127..150 CDD:275380 8/26 (31%)
leucine-rich repeat 151..174 CDD:275380 6/37 (16%)
leucine-rich repeat 175..198 CDD:275380 7/22 (32%)
leucine-rich repeat 199..222 CDD:275380 6/22 (27%)
leucine-rich repeat 223..246 CDD:275380 4/22 (18%)
leucine-rich repeat 247..270 CDD:275380 8/22 (36%)
leucine-rich repeat 271..294 CDD:275380 7/24 (29%)
leucine-rich repeat 295..318 CDD:275380 6/22 (27%)
leucine-rich repeat 319..337 CDD:275380 4/17 (24%)
leucine-rich repeat 343..367 CDD:275380 2/23 (9%)
leucine-rich repeat 368..388 CDD:275380 6/19 (32%)
leucine-rich repeat 392..417 CDD:275380 5/24 (21%)
leucine-rich repeat 443..469 CDD:275380 6/25 (24%)
leucine-rich repeat 470..492 CDD:275380 7/27 (26%)
leucine-rich repeat 493..516 CDD:275380 8/45 (18%)
leucine-rich repeat 517..541 CDD:275380 9/25 (36%)
leucine-rich repeat 542..570 CDD:275380 7/27 (26%)
leucine-rich repeat 571..594 CDD:275380 10/29 (34%)
leucine-rich repeat 596..617 CDD:275380 7/22 (32%)
leucine-rich repeat 618..641 CDD:275380 8/44 (18%)
LRR_8 640..698 CDD:316378 16/120 (13%)
leucine-rich repeat 642..665 CDD:275380 8/22 (36%)
leucine-rich repeat 716..803 CDD:275380 20/101 (20%)
PLN00113 <758..864 CDD:331614 19/86 (22%)
leucine-rich repeat 804..825 CDD:275380 6/25 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.