Protein Alignment Tollo and CG5810

DIOPT Version :10

• Sequence 1: NP_524757.1
• Gene: Tollo / 44497
• FlyBaseID: FBgn0029114
• Length: 1346
• Species: Drosophila melanogaster
• Sequence 2: NP_650952.2
• Gene: CG5810 / 42513
• FlyBaseID: FBgn0038866
• Length: 428
• Species: Drosophila melanogaster
• Alignment Length: 414
• Identity: 90/414 - (21%)
• Similarity: 158/414 - (38%)
• Gaps: 99/414 - (23%)

  Fly   182 NASYNKIQDISNFYFSASLSSRKARVCGSTLQSLDLSANKMVSLPTAMLSALGRLTHLNMAKNSM 246
            |..|.....::  |||.:::....:     .::|.|.::.:.:||..:...|.:|...::.:..:
  Fly    42 NLKYPSASAVA--YFSENVTKHLRK-----YETLVLHSSDLANLPRKIFLNLPQLVEFHVLECEL 99

  Fly   247 SFLADRAFEGLLSLRVVDLSANRLTSLPPELFAETKQLQEIYLRNNSINVLAPGIFGELAELLVL 311
            ..:....|:|..:|:.::...|.|..|....|....||:|:.|.:|.:..|...||..
  Fly   100 QQIESVCFDGAKNLKRLNFGGNALRVLDSNTFELATQLEELNLSDNQLEDLPTTIFRP------- 157

  Fly   312 DLASNELNSQWINAATFVGLKRLMMLDLSANKISRLEAHIFRPLASLQILKLEDNYIDQLPGGIF 376
                               ||.|..::||.|::..|..|||..|.||:.:.::.|.:.:|||.:|
  Fly   158 -------------------LKNLQKINLSNNRLITLSQHIFSQLGSLKSINVDSNQLVELPGELF 203

  Fly   377 ADLTNLHTLILSRNRISVIEQRTLQGLKNLLVLSLDFNRISRMDQRSLVNCSQLQDLHLND--NK 439
            .|         .|..:|....::.|      ::.:.||....:|..||....||:.|||:.  |:
  Fly   204 RD---------QRKHLSEFSAQSNQ------LVRIPFNIFREIDHLSLSFNPQLRRLHLSAKINE 253

  Fly   440 LQAV-------------------------------PEALAHVQLLKT----------------LD 457
            |:|.                               |:.|.|:.|..|                ||
  Fly   254 LEATNCDLESVELDGRVIGVQLEANPKLHELKISQPQDLEHLYLANTNLYRLDFLSKASKLVDLD 318

  Fly   458 VGENMISQIENTSITQLESLYGLRMTENSLTHIRRGVFDRMSSLQILNLSQNKLKSIEAGSLQRN 522
            | .::::..:...||..:.|..|..|.::||.....:...:..|..|.:|..|.|.|....|..:
  Fly   319 V-TDIVNLADLPKITSAKGLERLSFTYDNLTSNHMDMLPHLKDLNYLEISHEKGKEIFIKDLDED 382

  Fly   523 SQLQAIRLDGNQLKSIAGLFTELP 546
            ..::...|:..||..:.. |.|||
  Fly   383 FFVEEAELNCGQLADLLE-FVELP 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tollo	NP_524757.1	LRR	54..400	CDD:443914	47/217 (22%)
		leucine-rich repeat	100..123	CDD:275380
		leucine-rich repeat	124..144	CDD:275380
		leucine-rich repeat	154..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380	5/18 (28%)
		leucine-rich repeat	212..235	CDD:275380	5/22 (23%)
		leucine-rich repeat	236..259	CDD:275380	3/22 (14%)
		LRR	239..634	CDD:443914	79/357 (22%)
		leucine-rich repeat	260..283	CDD:275380	5/22 (23%)
		leucine-rich repeat	284..307	CDD:275380	7/22 (32%)
		leucine-rich repeat	308..333	CDD:275380	1/24 (4%)
		leucine-rich repeat	334..357	CDD:275380	9/22 (41%)
		leucine-rich repeat	358..381	CDD:275380	7/22 (32%)
		leucine-rich repeat	382..405	CDD:275380	3/22 (14%)
		leucine-rich repeat	406..429	CDD:275380	5/22 (23%)
		leucine-rich repeat	430..452	CDD:275380	10/54 (19%)
		leucine-rich repeat	453..500	CDD:275380	11/62 (18%)
		leucine-rich repeat	501..521	CDD:275380	7/19 (37%)
		leucine-rich repeat	525..547	CDD:275380	7/22 (32%)
		leucine-rich repeat	548..573	CDD:275380
		leucine-rich repeat	604..640	CDD:275380
		LRR_8	616..>660	CDD:404697
		leucine-rich repeat	641..688	CDD:275380
		leucine-rich repeat	689..816	CDD:275380
		LRR	<794..>920	CDD:443914
		leucine-rich repeat	817..864	CDD:275380
		leucine-rich repeat	865..888	CDD:275380
		leucine-rich repeat	889..910	CDD:275380
		TIR	1076..1211	CDD:214587
CG5810	NP_650952.2	LRR	<61..353	CDD:443914	71/338 (21%)
		leucine-rich repeat	65..88	CDD:275380	5/22 (23%)
		leucine-rich repeat	89..112	CDD:275380	3/22 (14%)
		leucine-rich repeat	113..136	CDD:275380	5/22 (23%)
		leucine-rich repeat	137..160	CDD:275380	8/48 (17%)
		leucine-rich repeat	161..184	CDD:275380	9/22 (41%)
		leucine-rich repeat	185..209	CDD:275380	8/32 (25%)
		leucine-rich repeat	210..231	CDD:275380	4/26 (15%)