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Protein Alignment Tollo and ltl

DIOPT Version :9

Sequence 1:	NP_524757.1	Gene:	Tollo / 44497	FlyBaseID:	FBgn0029114	Length:	1346	Species:	Drosophila melanogaster
Sequence 2:	NP_001261524.1	Gene:	ltl / 38845	FlyBaseID:	FBgn0268063	Length:	817	Species:	Drosophila melanogaster

Alignment Length:	575	Identity:	130/575 - (22%)
Similarity:	249/575 - (43%)	Gaps:	107/575 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 KSLQHLNASYNKIQDISNFYFSA---SLSSR-------KARVCGSTLQSLDLSA----------- 219
            |:..|:..|..|::.     |:|   ||:::       ..::..|.|..|::.:
  Fly    31 KAWNHVELSCEKLES-----FNAVVDSLANKLNADTNIDLKITHSQLDDLEMRSFTDMNFNLYKL 90

  Fly   220 ----NKMVSLPTAMLSALGRLTHLNMAKNSMSFLADRAFEGLLSLRVVDLSANRLTSLPPELFAE 280
                |.:.|||......|..:|:|::..|.:..:...|...:.||..:|:...::.::..|.|..
  Fly    91 RMQWNSLKSLPEVPFRGLSNVTYLSIGDNDLDEIPKHALSHMPSLLTLDIGRCKIRAVQQEDFRG 155

  Fly   281 TKQLQEIYLRNNSINVLAPGIFGELAELLVLDLASNELNSQWINAATFVGLKRLMMLDLSANKIS 345
            .:::..:.|.:|.|..|..|.|.:  .||:|.|..|:|.|  :|.:.. .|..|..|.::||.|:
  Fly   156 IQRVTNLILVSNIITRLDRGSFPK--SLLILHLGRNQLES--LNGSLH-DLHNLESLFINANNIT 215

  Fly   346 RLEAHIFRPLASLQILKLEDNYIDQLPGGIFADLTNLHTLILSRNRISVIEQRTLQGLKNLLVLS 410
            .|:..: .....|::|...:|.:::||..: |.:.:|.|:.:..|::...: |.|:...||..:.
  Fly   216 SLDDEL-PDGGQLRLLMAHNNRLERLPANM-AGMHSLETVHIHCNQLRSFD-RVLRNAVNLSEVM 277

  Fly   411 LDFNRISRMDQRSLVNCSQLQDLHLNDNKLQAVPEALAHVQLLKTLDVGENMISQIENTSITQLE 475
            .|.|.:..:.|....:||:::.|.:..|.::::..:|..:..||..:...|.|.:.....:..|.
  Fly   278 ADNNELEYLAQDEFASCSKVETLQMGCNHIKSLNSSLLPILKLKNANFSFNDIEEFSMAELHGLR 342

  Fly   476 SLYGLRMTENSLTHI---RRGVFDRMSSLQILNLSQNKLKSIEAGSLQRNSQLQAIRLDGNQLKS 537
            ||..|:::.|.:..:   .|||    ..|.::||.                      ||.|::.|
  Fly   343 SLKTLQLSSNRIQRLLPDPRGV----QELMLVNLD----------------------LDNNRIDS 381

  Fly   538 IAGLFTELPNLVWLNISGNRLEKFDYSHIPIGLQWLDVRANRITQLGNYFEIESELSLSTFDASY 602
            :.|....|.||..||::|||||     |:.:|                  :.:..:.|...|.:.
  Fly   382 LNGALAGLGNLRILNLAGNRLE-----HLQVG------------------DFDGMIRLDILDLTG 423

  Fly   603 NLLTE---ITASSIPNSVEVLYLNDNQISKIQPYTFFKKPNLTRVDLVRNRLTTLEPNALRLSPI 664
            |.|.|   :..:.:| |:::|.:..|.|:|:: ..|...|.|.:.:|..|:::|:. :.|..:..
  Fly   424 NQLAELKPLEMTLLP-SLKILKVAYNNITKLE-QDFKGLPVLCQANLTNNQISTIS-SELVTNTR 485

  Fly   665 AEDREIP---EFYIGHNAYECD------CNLDWLQKVNRESRTQPQLMDLDQIHC 710
            .::..:|   |.::..|...||      |.|..:|:.....|:  |..:.||..|
  Fly   486 CKNHNVPGKLEIHLDDNPIMCDVGLNELCRLMAVQEARIRGRS--QCFENDQEVC 538

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.