Protein Alignment Tollo and CG5096

DIOPT Version :10

• Sequence 1: NP_524757.1
• Gene: Tollo / 44497
• FlyBaseID: FBgn0029114
• Length: 1346
• Species: Drosophila melanogaster
• Sequence 2: NP_723576.1
• Gene: CG5096 / 34410
• FlyBaseID: FBgn0032235
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 93/361 - (25%)
• Similarity: 155/361 - (42%)
• Gaps: 62/361 - (17%)

  Fly   239 LNMAKNSMSFLADRAFEGLLS----LRVVDLSANRLTSLP--PELFAETKQLQEIYLRNNSINVL 297
            |:.::....:|:...:|.|.:    .:.::|..|.|||:|  |:.     .::.:||.||.|:.:
  Fly    59 LDCSEKLQDWLSAEDWEDLTNGNVVFKTINLEHNNLTSVPILPKY-----DVENLYLANNQIDSI 118

  Fly   298 APGIFGELAELLVLDLASNELNSQWINAATFVGLKRLMMLDLSANKISRLEAHIFRPLASLQILK 362
            :.|.|..|.||:.|||:.|.|.|:.:....|.|               ......|..|.:|:.|.
  Fly   119 SVGAFQNLTELVTLDLSHNRLTSKVLVPDVFKG---------------PFTVQDFESLENLKTLN 168

  Fly   363 LEDNYIDQLPGGIFADLTNLHTLILSRNRISVIEQ---RTLQGLKNLLVLSLDFNRISRMDQRSL 424
            |..|.:..|...:|..:.::..|:|..|...||:|   ..:.||::|.:|.:.:..|..:....|
  Fly   169 LGYNDLHSLDADLFEHIPHIEELVLCSNSFHVIDQLSETAISGLQSLKILDVSYMEIDDLPDTIL 233

  Fly   425 VNCSQLQDLHLNDNKLQAVPEALAHVQLLKTLDVGENMISQIENTSI-TQLESLYGLRMT-ENSL 487
            .....|:......|....:|:||.:...|.:|.:.||.|..:...:: ..|..|..|.|| .:.|
  Fly   234 HGPRDLEIFIAAGNLFNQLPKALKYATNLTSLVLNENPIENLIGDNVFPPLTKLTHLSMTFMSKL 298

  Fly   488 THIRRGVFDRMSSLQILNLSQNK-LKSIEAGSLQRNSQLQAIRLDGNQLKSIAGLFTELPNL--V 549
            ..|..|.|..:.||..|.||.|| |..|:..:|.:|       :.|.|       :.:.|.|  |
  Fly   299 YKIGPGAFSELQSLTELILSDNKLLNEIDEEALSKN-------VTGGQ-------YLDYPPLEKV 349

  Fly   550 WLNISGNRLEKFDYSHIP--IGLQW-----LDVRAN 578
            :||       ..:.|.:|  :.::|     ||:|.|
  Fly   350 YLN-------NCNVSTLPKELLVRWDKLKALDLRFN 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tollo	NP_524757.1	LRR	54..400	CDD:443914	43/169 (25%)
		leucine-rich repeat	100..123	CDD:275380
		leucine-rich repeat	124..144	CDD:275380
		leucine-rich repeat	154..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		leucine-rich repeat	212..235	CDD:275380
		leucine-rich repeat	236..259	CDD:275380	4/19 (21%)
		LRR	239..634	CDD:443914	93/361 (26%)
		leucine-rich repeat	260..283	CDD:275380	7/24 (29%)
		leucine-rich repeat	284..307	CDD:275380	8/22 (36%)
		leucine-rich repeat	308..333	CDD:275380	9/24 (38%)
		leucine-rich repeat	334..357	CDD:275380	2/22 (9%)
		leucine-rich repeat	358..381	CDD:275380	6/22 (27%)
		leucine-rich repeat	382..405	CDD:275380	8/25 (32%)
		leucine-rich repeat	406..429	CDD:275380	4/22 (18%)
		leucine-rich repeat	430..452	CDD:275380	5/21 (24%)
		leucine-rich repeat	453..500	CDD:275380	14/48 (29%)
		leucine-rich repeat	501..521	CDD:275380	9/20 (45%)
		leucine-rich repeat	525..547	CDD:275380	2/21 (10%)
		leucine-rich repeat	548..573	CDD:275380	7/33 (21%)
		leucine-rich repeat	604..640	CDD:275380
		LRR_8	616..>660	CDD:404697
		leucine-rich repeat	641..688	CDD:275380
		leucine-rich repeat	689..816	CDD:275380
		LRR	<794..>920	CDD:443914
		leucine-rich repeat	817..864	CDD:275380
		leucine-rich repeat	865..888	CDD:275380
		leucine-rich repeat	889..910	CDD:275380
		TIR	1076..1211	CDD:214587
CG5096	NP_723576.1	LRR	54..>322	CDD:443914	74/282 (26%)
		leucine-rich repeat	85..104	CDD:275380	7/23 (30%)
		leucine-rich repeat	105..128	CDD:275380	8/22 (36%)
		leucine-rich repeat	129..163	CDD:275380	11/48 (23%)
		leucine-rich repeat	164..187	CDD:275380	6/22 (27%)
		leucine-rich repeat	188..214	CDD:275380	8/25 (32%)
		leucine-rich repeat	215..238	CDD:275380	4/22 (18%)
		leucine-rich repeat	239..261	CDD:275380	5/21 (24%)
		leucine-rich repeat	262..286	CDD:275380	6/23 (26%)
		leucine-rich repeat	287..311	CDD:275380	8/23 (35%)
		leucine-rich repeat	346..369	CDD:275380	7/29 (24%)
		leucine-rich repeat	370..388	CDD:275380	4/9 (44%)