DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tollo and si:dkey-182i3.11

DIOPT Version :9

Sequence 1:NP_524757.1 Gene:Tollo / 44497 FlyBaseID:FBgn0029114 Length:1346 Species:Drosophila melanogaster
Sequence 2:XP_021322095.1 Gene:si:dkey-182i3.11 / 100334238 ZFINID:ZDB-GENE-121214-258 Length:710 Species:Danio rerio


Alignment Length:849 Identity:196/849 - (23%)
Similarity:314/849 - (36%) Gaps:265/849 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   157 LDLSLNNIW--------LIPDGMVCPLKSLQHLNASYNKIQDISNFYFSASLSSRKARVCGSTLQ 213
            :|:.:...|        .:|:|       .:|..|:.||||.:.|..|             ..|:
Zfish    62 VDVDIVTCWNTNLLEFPPLPNG-------TKHFYATRNKIQALPNETF-------------HELR 106

  Fly   214 SLDLSANKM-VSLPTAMLSALGRLTHLNMAKNSMSFLADRAFEGLLSLRVVDLSANRLTSLPPEL 277
            .|||:.|.. :||.|...|..| ||||::..|.:..|..|.|||||:|:|:|||.|.:.|| |::
Zfish   107 VLDLTKNVFNLSLNTNWQSVRG-LTHLHLGGNRLRALTPRQFEGLLNLQVLDLSNNAIKSL-PQM 169

  Fly   278 F------AETKQLQ-------------------EIYLRNNSINVLAPGIFGELAELLVLDLASNE 317
            |      .:|..|.                   ::.||:|.|:::...:|.....|..|.|:.|:
Zfish   170 FLYGLINLQTLNLNINQILSLSYGVLEGPLALTDLQLRDNMIDMIEMNVFENCTYLAKLYLSKNK 234

  Fly   318 LNSQWINAATFVGLKRLMMLDLSANKISRLEAHIFRPLASLQILKLEDNYIDQLPGGIFADLTNL 382
            |.|  :...:|.|...|..|||..|.::.:...:.:..::|..|.|:.|.|..:|..:|:::.:|
Zfish   235 LKS--VGNGSFKGATGLNHLDLGLNGLAGIPTIVLQETSNLTSLYLQKNDITSIPDNVFSEILSL 297

  Fly   383 HTLILSRNRISVIEQRTLQGLKNLLVLSLDFNRISRMDQRSLVNCSQLQDLHLNDNKLQAVPEAL 447
            ..|.||.|.:..|...:.:.|..|:.|.|.||::..:.|....:..:|::|:|..|||.::|..:
Zfish   298 KHLDLSYNGLVSISNGSFRSLSQLVYLDLSFNQLQTLTQHVFEDLGKLENLNLYHNKLTSLPNNM 362

  Fly   448 -AHVQLLKTLDVGENMISQIENTSITQLESLYGLRMTENSLTHIRRGVFDRMSSLQILNLSQNKL 511
             .::.:||.|.:..|.||.|.......|.:|..|::..|.::.:....|.::..|:.|::|.|.|
Zfish   363 FKNLTMLKELQLDSNNISVIPPDLFHPLSALKDLQLDNNHISKLHSHTFKKLRQLKQLDISSNDL 427

  Fly   512 KSIEAGSLQRNSQLQAIRLDGNQLKSIAGL-FTELPNLVWLNISGNRLEKFDYSHIPIGLQWLDV 575
            ..|......:|  |:.:.|:.|.:..|:.. |..|..|..|.:|.|.|.|.              
Zfish   428 TKIPNHLFHKN--LKELNLENNHISFISKFSFKNLHRLQSLKLSHNNLSKL-------------- 476

  Fly   576 RANRITQLGNYFEIESELSLSTFDASYNLLTEITASSIPNSVEVLYLNDNQISKIQPYTFFK-KP 639
                      |.|               |||.:|      .:..|.||:|||..| |..||| ..
Zfish   477 ----------YRE---------------LLTNLT------RLRELLLNENQIETI-PVGFFKGLE 509

  Fly   640 NLTRVDLVRNRLTTLEPNALR-LSPIAEDREIPEFYIGHNAYECDCNLDWLQKVNRESRTQPQLM 703
            ||..:||..|::..:.|:|.. ||                                      .|.
Zfish   510 NLRVLDLSNNKMHFILPDAFNDLS--------------------------------------ALK 536

  Fly   704 DLDQIHCRLAYARGSSHVSLIEAKSDDFLCKYASHCFALCHCCDFQACDCKMECPDRCSCYHDQS 768
            |||                                                              
Zfish   537 DLD-------------------------------------------------------------- 539

  Fly   769 WTSNVVDCSRASYEQTLPSHIPMDSTQLYLDGNNFRELQSHAFIGRKRLKVLHLNHSRIEVLHNR 833
                                         |..|....|....|...:.|..|||.::::..|.:|
Zfish   540 -----------------------------LSFNFLHNLPEDIFASLRNLTKLHLQNNKLRYLPSR 575

  Fly   834 TFYGLLELEVLQLQSNQLKALNGNEFQGLDNLQELYLQHNAIATIDTLTFTHLYHLKILRLDHNA 898
            .|..|:.||.|.|..|.::.::..:|:||..|.||.::.|.:.:::..|...|..||.:.||   
Zfish   576 LFSALVGLEELHLDRNYIQRIHPTQFEGLVKLHELDMKSNQLRSMEDGTLMPLRKLKRIHLD--- 637

  Fly   899 ITSFAVWNFLPSYLNELRLASNPWTCSCEFIDKLRDYINRHEYVVDKLKMKCDVISGNSTQQMVI 963
                                .|||.||...|..:..:.|.:..:|....| |.  ||.:.....:
Zfish   638 --------------------GNPWDCSTVVILYISQWFNNNTQLVKTTPM-CS--SGQNLSNPAL 679

  Fly   964 YPGS 967
            :|.|
Zfish   680 FPSS 683

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TolloNP_524757.1 LRR_RI <85..281 CDD:238064 44/138 (32%)
leucine-rich repeat 100..123 CDD:275380
leucine-rich repeat 124..144 CDD:275380
LRR_8 152..222 CDD:290566 17/72 (24%)
leucine-rich repeat 154..177 CDD:275380 4/27 (15%)
leucine-rich repeat 178..201 CDD:275380 8/22 (36%)
LRR 210..656 CDD:227223 132/474 (28%)
leucine-rich repeat 212..235 CDD:275380 9/23 (39%)
leucine-rich repeat 236..259 CDD:275380 11/22 (50%)
leucine-rich repeat 260..283 CDD:275380 11/28 (39%)
LRR_RI 276..558 CDD:238064 77/308 (25%)
leucine-rich repeat 284..307 CDD:275380 6/41 (15%)
leucine-rich repeat 308..333 CDD:275380 8/24 (33%)
leucine-rich repeat 334..357 CDD:275380 5/22 (23%)
leucine-rich repeat 358..381 CDD:275380 7/22 (32%)
leucine-rich repeat 382..405 CDD:275380 7/22 (32%)
leucine-rich repeat 406..429 CDD:275380 6/22 (27%)
leucine-rich repeat 430..452 CDD:275380 7/22 (32%)
leucine-rich repeat 453..500 CDD:275380 12/46 (26%)
leucine-rich repeat 501..521 CDD:275380 6/19 (32%)
leucine-rich repeat 525..547 CDD:275380 6/22 (27%)
leucine-rich repeat 548..573 CDD:275380 6/24 (25%)
leucine-rich repeat 604..640 CDD:275380 15/36 (42%)
leucine-rich repeat 641..688 CDD:275380 8/47 (17%)
leucine-rich repeat 689..816 CDD:275380 8/126 (6%)
LRR_8 815..875 CDD:290566 20/59 (34%)
leucine-rich repeat 817..864 CDD:275380 16/46 (35%)
LRR_8 864..921 CDD:290566 10/56 (18%)
leucine-rich repeat 865..888 CDD:275380 6/22 (27%)
leucine-rich repeat 889..910 CDD:275380 4/20 (20%)
TIR 1076..1211 CDD:214587
si:dkey-182i3.11XP_021322095.1 PLN00113 97..>617 CDD:331614 166/713 (23%)
leucine-rich repeat 129..152 CDD:275380 11/22 (50%)
leucine-rich repeat 153..176 CDD:275380 10/23 (43%)
leucine-rich repeat 177..200 CDD:275380 2/22 (9%)
leucine-rich repeat 201..224 CDD:275380 5/22 (23%)
leucine-rich repeat 225..248 CDD:275380 8/24 (33%)
leucine-rich repeat 249..272 CDD:275380 5/22 (23%)
leucine-rich repeat 273..296 CDD:275380 7/22 (32%)
leucine-rich repeat 297..320 CDD:275380 7/22 (32%)
leucine-rich repeat 321..344 CDD:275380 6/22 (27%)
leucine-rich repeat 345..368 CDD:275380 7/22 (32%)
leucine-rich repeat 369..392 CDD:275380 8/22 (36%)
leucine-rich repeat 393..438 CDD:275380 10/44 (23%)
leucine-rich repeat 417..436 CDD:275380 6/18 (33%)
leucine-rich repeat 439..462 CDD:275380 6/22 (27%)
leucine-rich repeat 463..486 CDD:275380 12/67 (18%)
leucine-rich repeat 487..510 CDD:275380 11/23 (48%)
leucine-rich repeat 511..534 CDD:275380 8/60 (13%)
leucine-rich repeat 535..558 CDD:275380 8/113 (7%)
leucine-rich repeat 559..582 CDD:275380 8/22 (36%)
leucine-rich repeat 583..606 CDD:275380 8/22 (36%)
leucine-rich repeat 607..628 CDD:275380 5/20 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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