| Sequence 1: | NP_524756.2 | Gene: | Uba2 / 44496 | FlyBaseID: | FBgn0029113 | Length: | 700 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003959.3 | Gene: | UBA3 / 9039 | HGNCID: | 12470 | Length: | 463 | Species: | Homo sapiens |
| Alignment Length: | 571 | Identity: | 142/571 - (24%) |
|---|---|---|---|
| Similarity: | 208/571 - (36%) | Gaps: | 222/571 - (38%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 9 FPP---TLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHV 70
Fly 71 GKSKARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCL--- 132
Fly 133 ---------NADVPLIESGTAGYNGQVELIKRGLTQCYECTPK--DKQRSFPGCTIRNTPSEPIH 186
Fly 187 CIVWAKHLFNQLFGESLEDEDISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTA 251
Fly 252 NGNIMRINTRQWAKDCNYDAGKLFNKFFNEDITYLLRMSNLWKTRKAPVPVQWDTLLPEGSSGDQ 316
Fly 317 KDVAKQHHKVWSIEECAQVFANSLKELSANFLKLEGDDTLAWDKDDQPAMDFVAACANVRSHIFD 381
Fly 382 IERKSRFEIK--------SMAGNIIPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPNA 438
Fly 439 RNHFLVPDASLPG---------PNPNCHVCASDPA-ITLKIDTKRMRI---------KELRDEVL 484
Fly 485 VKTLNMLNPDVTVQSNGSILISSEEGETECNDGKLLSELNIVDGVILKCDD 535 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Uba2 | NP_524756.2 | ThiF | 7..>177 | CDD:279270 | 75/184 (41%) |
| Uba2_SUMO | 21..459 | CDD:238766 | 115/468 (25%) | ||
| UAE_UbL | 467..552 | CDD:291402 | 19/78 (24%) | ||
| UBA2_C | 573..691 | CDD:292812 | |||
| UBA3 | NP_003959.3 | Interaction with UBE2M N-terminus | 53..70 | 5/13 (38%) | |
| Uba3_RUB | 71..368 | CDD:238765 | 115/469 (25%) | ||
| Interaction with UBE2M N-terminus | 157..161 | 1/3 (33%) | |||
| Interaction with UBE2M N-terminus | 192..217 | 9/24 (38%) | |||
| Interaction with NEDD8 | 227..229 | 0/1 (0%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 242..248 | 2/5 (40%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 292..295 | 0/2 (0%) | |||
| Interaction with UBE2M N-terminus | 331..338 | 1/13 (8%) | |||
| Interaction with NEDD8 | 352..357 | 0/4 (0%) | |||
| Interaction with UBE2M core domain | 368..463 | 21/86 (24%) | |||
| E2_bind | 376..461 | CDD:400951 | 19/78 (24%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0476 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D686413at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||