DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba2 and ATG7

DIOPT Version :9

Sequence 1:	NP_524756.2	Gene:	Uba2 / 44496	FlyBaseID:	FBgn0029113	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_012041.1	Gene:	ATG7 / 856576	SGDID:	S000001214	Length:	630	Species:	Saccharomyces cerevisiae

Alignment Length:	185	Identity:	49/185 - (26%)
Similarity:	78/185 - (42%)	Gaps:	26/185 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGK 72
            :.|....:::|.:|||::|||.:||.|.:.|:..|...|..:|..|:..||..||.|::.|..||
Yeast   313 ILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGK 377

  Fly    73 SKARVARESALSFNPDAKITAYHDSVTSTDYG-VN-------------FFKKFDLVLSALDNRAA 123
            .||.:|..|.....|....|....|:....:. ||             ..|:.|::...:|:|.:
Yeast   378 PKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDIIFLLVDSRES 442

  Fly   124 R-------NHVNRMCLNADVPLIESGTAGYNGQVELIKRGLTQCYEC----TPKD 167
            |       |..|:..:||.:.........:..:.|...:.| .||.|    .|.|
Yeast   443 RWLPSLLSNIENKTVINAALGFDSYLVMRHGNRDEQSSKQL-GCYFCHDVVAPTD 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	49/185 (26%)
		Uba2_SUMO	21..459	CDD:238766	47/172 (27%)
		UAE_UbL	467..552	CDD:291402
		UBA2_C	573..691	CDD:292812
ATG7	NP_012041.1	E1_like_apg7	9..628	CDD:273590	49/185 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900