DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba2 and UBA3

DIOPT Version :9

Sequence 1:	NP_524756.2	Gene:	Uba2 / 44496	FlyBaseID:	FBgn0029113	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_015391.1	Gene:	UBA3 / 856179	SGDID:	S000006270	Length:	299	Species:	Saccharomyces cerevisiae

Alignment Length:	180	Identity:	70/180 - (38%)
Similarity:	106/180 - (58%)	Gaps:	18/180 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 KVLVVGAGGIGCEVLKNLVLSGFT-DIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVARESALS 84
            |:||:||||:|||:||||.:..|. .:.|:|:|||:|:||||||||..:.:||.||:||.:...:
Yeast     4 KILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYVNT 68

  Fly    85 FNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVN----RMCLNAD----VPLIES 141
            ..|..::.|:...:|:..  .:|:|.|..::|.||....|..:|    ::.|.::    :|.|:.
Yeast    69 RFPQLEVVAHVQDLTTLP--PSFYKDFQFIISGLDAIEPRRFINETLVKLTLESNYEICIPFIDG 131

  Fly   142 GTAGYNGQVELIKRGLTQCYEC---TPKDKQRSFPGCTIRNTPSEPIHCI 188
            ||.|..|.|:.|..|:|.|:||   |...:|.:.|.|||.|.|    .||
Yeast   132 GTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMCTIANNP----RCI 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	64/167 (38%)
		Uba2_SUMO	21..459	CDD:238766	70/180 (39%)
		UAE_UbL	467..552	CDD:291402
		UBA2_C	573..691	CDD:292812
UBA3	NP_015391.1	Uba3_RUB	4..294	CDD:238765	70/180 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810