Protein Alignment Uba2 and UBA1

DIOPT Version :9

• Sequence 1: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_012712.1
• Gene: UBA1 / 853670
• SGDID: S000001693
• Length: 1024
• Species: Saccharomyces cerevisiae
• Alignment Length: 668
• Identity: 180/668 - (26%)
• Similarity: 277/668 - (41%)
• Gaps: 168/668 - (25%)

  Fly     8 VFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTD-----IEIIDLDTIDLSNLNRQFLFHR 67
            ||....|:.:..|||.:||:|.||||:|||..|.|...     |.:.|.|:|:.|||||||||..
Yeast   423 VFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRP 487

  Fly    68 EHVGKSKARVARESALSFNPD--AKITAYHDSV---TSTDYGVNFFKKFDLVLSALDNRAARNHV 127
            :.|||:|:.||.|:..:.|||  .||.|..|.|   |...:..:|::..|.|.:||||..||.:|
Yeast   488 KDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYV 552

  Fly   128 NRMCLNADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAK 192
            :|.|:....||:||||.|..|..::|...||:.|..:....::|.|.||:|:.|::..|.|.|||
Yeast   553 DRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAK 617

  Fly   193 HLFNQLFGESLEDEDI---SPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANGN 254
            .||...|.:|.|:.::   .|:..:...|:      :|:.||..:...:....:....||..
Yeast   618 SLFQGYFTDSAENVNMYLTQPNFVEQTLKQ------SGDVKGVLESISDSLSSKPHNFEDCI--- 673

  Fly   255 IMRINTRQWAKDCNYDAGKLFNKFFNEDITYLL-------RMSN---LWK-TRKAPVPVQWDT-- 306
                   :||:       ..|.|.||.||..||       :.||   .|. .::||.|:::|.
Yeast   674 -------KWAR-------LEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYN 724

  Fly   307 -----LLPEGSS------GDQKDVAKQHHKVWSIEECAQVF------------------------ 336
                 .:..|:|      |.:.|.:....   :::|...|.
Yeast   725 NDHFHFVVAGASLRAYNYGIKSDDSNSKP---NVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPD 786

  Fly   337 -----ANSLKELSANFLKLEGDDTLA--------WDKDDQP--AMDFVAACANVRSHIFDIERKS 386
                 ||...|:......|....|||        ::|||..  .::|:.||:|.|:..:.||...
Yeast   787 PNANAANGSDEIDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETAD 851

  Fly   387 RFEIKSMAGNIIPAIATTNAITAGISVMRAFKVLEAKW--EQCKAVYARLRPNARNHFLVPDASL 449
            |.:.|.:||.||||||||.::..|:..:..:|:::.|.  ||.|..:..|             :|
Yeast   852 RQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNL-------------AL 903

  Fly   450 PGPNPNCHVCASDPAITLKIDTKRMRIKELRDEVLVKTLNMLNPDVTVQSNGSILISSEEGETEC 514
            |      ....|:|..:.|.:....:..::.|...:|              |.|.:|......|.
Yeast   904 P------FFGFSEPIASPKGEYNNKKYDKIWDRFDIK--------------GDIKLSDLIEHFEK 948

  Fly   515 NDGKLLSELNIVDGVILKCDDFFQNYELS-------------IIISHFDAERDENLFEVVADASQ 566
            ::|..::.|:.  ||.|....||...:|.             :......|.....:.|:.||
Yeast   949 DEGLEITMLSY--GVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICAD--- 1008

  Fly   567 LKPKDEDQKEAVKDKEDE 584
                         |||.|
Yeast  1009 -------------DKEGE 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	74/178 (42%)
		Uba2_SUMO	21..459	CDD:238766	151/515 (29%)
		UAE_UbL	467..552	CDD:291402	15/97 (15%)
		UBA2_C	573..691	CDD:292812	4/12 (33%)
UBA1	NP_012712.1	Ube1	13..1023	CDD:273603	180/668 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810