DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba2 and Atg7

DIOPT Version :9

Sequence 1:	NP_524756.2	Gene:	Uba2 / 44496	FlyBaseID:	FBgn0029113	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_001240646.1	Gene:	Atg7 / 74244	MGIID:	1921494	Length:	741	Species:	Mus musculus

Alignment Length:	136	Identity:	37/136 - (27%)
Similarity:	54/136 - (39%)	Gaps:	22/136 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PTLQ-ELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHV---G 71
            |||. :.|...|.|::|||.:||.|.:.|:..|...:..:|...|..||..||.|:..|..   |
Mouse   385 PTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGG 449

  Fly    72 KSKARVARESALSFNPDAKITAYHDSVTSTDYGVNF------------------FKKFDLVLSAL 118
            |.||..|.|......|......::.|:....:.|||                  ....|::...:
Mouse   450 KPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLM 514

  Fly   119 DNRAAR 124
            |.|.:|
Mouse   515 DTRESR 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	37/136 (27%)
		Uba2_SUMO	21..459	CDD:238766	33/125 (26%)
		UAE_UbL	467..552	CDD:291402
		UBA2_C	573..691	CDD:292812
Atg7	NP_001240646.1	ATG7_N	52..359	CDD:293029
		E1_like_apg7	54..740	CDD:273590	37/136 (27%)
		Apg7	396..720	CDD:238763	33/125 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900