Protein Alignment Uba2 and Uba7

DIOPT Version :9

• Sequence 1: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_076227.1
• Gene: Uba7 / 74153
• MGIID: 1349462
• Length: 977
• Species: Mus musculus
• Alignment Length: 561
• Identity: 148/561 - (26%)
• Similarity: 220/561 - (39%)
• Gaps: 152/561 - (27%)

  Fly     8 VFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGF-----TDIEIIDLDTIDLSNLNRQFLFHR 67
            ||...|||.:.....|:||||.||||:||...|.|.     ..:.:.|:|.|:.|||:|||||..
Mouse   408 VFGTDLQEKLSDQHYLLVGAGAIGCEMLKVFALVGLGVRANGGVTVADMDYIERSNLSRQFLFRP 472

  Fly    68 EHVGKSKARVARESALSFNPDAKITAYH---DSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNR 129
            :.|.:.||.||..:|...|||.:.|.|.   |..|...|..:||.:.:.|::|||:..||::|..
Mouse   473 KDVRRPKAEVAAAAAHRLNPDLRATPYTCPLDPTTEDIYDDSFFSRVNGVVAALDSFQARHYVAA 537

  Fly   130 MCLNADVPLIESGTAGYNGQVELIKRGLTQCYECTPKD---KQRSFPGCTIRNTPSEPIHCIVWA 191
            .|.:...||:|:||.|..|...:....:|:.|.....|   :...:|.||:|:.||...|.:.||
Mouse   538 RCTHYLKPLLEAGTQGTWGSASVFVPYVTEAYRGPASDAASEDAPYPVCTLRHIPSSMEHSVQWA 602

  Fly   192 KHLFNQLFGESLEDED------ISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDT 250
            :..|..||..|.|..:      .|..|.|                          :.|..|....
Mouse   603 QDQFEGLFRLSTETINCYQQTCTSLSATD--------------------------RTETLALLQQ 641

  Fly   251 ANGNIMRINTRQWAKDC---------------NYDAGKLFNKFFNE-------------DITYLL 287
            ..| ::|...:.| :||               ..:.|..|:...|:             ...|:|
Mouse   642 VMG-VLRTRPQTW-QDCVVWALGHWQLCFHDKVLEGGTQFSSGSNKCPHPLQFDPNHDMHFLYVL 704

  Fly   288 RMSNLWK-------TRKAPVPVQWDTLLPEGSSGDQKDVAKQHHKVWSIEECAQVFANSLKELSA 345
            ..:||:.       ::..|...:..|.|.|..|..|...:.:|.:            ..||||..
Mouse   705 AAANLYARMHGLPGSQSQPALRELLTRLLESDSRPQNLFSAEHGQ------------EQLKELQE 757

  Fly   346 NFLKLEGDDTLAW-------------DKDDQPAMDFVAACANVRSHIFDIERKSRFEIKSMAGNI 397
            ..     ||   |             |.|....:|||.|..::|...:.|...:...||.:.|.|
Mouse   758 TL-----DD---WRKGPPLKPVLFVKDDDSNFHVDFVVAATDLRCQNYGILPVNHARIKQIVGRI 814

  Fly   398 IPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPN----------ARNHFLVPDASLPGP 452
            ||||||:.|:.||:..:..:||:..           ||.:          |.|||:   .|.|
Mouse   815 IPAIATSTAVVAGLLGLELYKVVSG-----------LRSHGTFRHSYLHLAENHFI---RSAP-- 863

  Fly   453 NPNCHVCASDPAITLKIDTK-----RMRIKELRDEVLVKTL 488
                    |.||:....|.|     |:::..::.|..:|:|
Mouse   864 --------SAPAVQSFRDLKWTCWDRLKVPAVQPERTLKSL 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	65/179 (36%)
		Uba2_SUMO	21..459	CDD:238766	134/512 (26%)
		UAE_UbL	467..552	CDD:291402	6/27 (22%)
		UBA2_C	573..691	CDD:292812
Uba7	NP_076227.1	Ube1	1..961	CDD:273603	148/561 (26%)
		Ube1_repeat1	5..386	CDD:238768
		E1_4HB	254..317	CDD:292809
		E1_enzyme_family	421..932	CDD:304554	143/548 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810