Protein Alignment Uba2 and Uba2

DIOPT Version :10

• Sequence 1: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_057891.1
• Gene: Uba2 / 50995
• MGIID: 1858313
• Length: 638
• Species: Mus musculus
• Alignment Length: 705
• Identity: 333/705 - (47%)
• Similarity: 448/705 - (63%)
• Gaps: 76/705 - (10%)

  Fly     4 AINGVFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHRE 68
            |::...|..|.|.|...:||||||||||||:||||||:||:.|::|||||||:|||||||||.::
Mouse     2 ALSRGLPRELAEAVSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKK 66

  Fly    69 HVGKSKARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCLN 133
            |||:|||:||:||.|.|:|.|.|.|:|||:.:.||.|.||::|.||::||||||||||||||||.
Mouse    67 HVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLA 131

  Fly   134 ADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAKHLFNQL 198
            |||||||||||||.|||..||:|:|:||||.||..||:|||||||||||||||||||||:|||||
Mouse   132 ADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQL 196

  Fly   199 FGESLEDEDISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANGNIMRINTRQW 263
            |||...|:::|||.|||:|                  ..|.::.|..|:....:|:|.||:|::|
Mouse   197 FGEEDADQEVSPDRADPEA------------------AWEPTEAEARARASNEDGDIKRISTKEW 243

  Fly   264 AKDCNYDAGKLFNKFFNEDITYLLRMSNLWKTRKAPVPVQWDTLLPEG-SSGDQKD---VAKQHH 324
            ||...||..|||.|.|.:||.|||.|..||:.||.|||:.|..:..:| ::.||::   :..:..
Mouse   244 AKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEANADQQNEPQLGLKDQ 308

  Fly   325 KVWSIEECAQVFANSLKELSANFLKLEGDDT-LAWDKDDQPAMDFVAACANVRSHIFDIERKSRF 388
            :|..::..|.:|:.|::.|..: |..:||.. |.|||||.||||||.:.||:|.|||.:..||||
Mouse   309 QVLDVKSYASLFSKSIETLRVH-LAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRF 372

  Fly   389 EIKSMAGNIIPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPNARNHFLVPDASLPGPN 453
            :|||||||||||||||||:.||:.|:...|:|..|.:||:.::...:||.|...||| .:|..||
Mouse   373 DIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVP-CALDPPN 436

  Fly   454 PNCHVCASDPAITLKIDTKRMRIKELRDEVLVKTLNMLNPDVTVQ-SNGSILISSEEGETECNDG 517
            .||:||||.|.:|::::..::.:..|:|:::.:...|:.|||.:: ..|:|||||||||||.|:.
Mouse   437 TNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNP 501

  Fly   518 KLLSELNIVDGVILKCDDFFQNYELSIIISHFDAERDENLFEVVADASQLKPKDEDQKEAVKDKE 582
            |.||:..|.:|..|:.|||.|:|.|.|.|.|.:....:..||||.|:        .:|...|..|
Mouse   502 KKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDS--------PEKVGPKQAE 558

  Fly   583 DEPKSAKKRSTNGEGDSKDDG--PSTSKRSRPNEVVEEDDDDCLVIEEDEDQADVVVVATDKLSV 645
            |..||.    .||    .|||  ||||        ..::.||.|:::.||:...   .:||
Mouse   559 DAAKSI----ANG----SDDGAQPSTS--------TAQEQDDVLIVDSDEEGPS---NSTD---- 600

  Fly   646 QSPPKSGSKRKPCEVIEDEDITEILESSDDEPAGPTKCKRSRLDDSNPVAVISID 700
            .|......|||             ||  ::|.|...||:..:::|  |..||::|
Mouse   601 CSGDDKARKRK-------------LE--ENEAASTKKCRLEQMED--PDDVIALD 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	Uba2_SUMO	21..459	CDD:238766	246/442 (56%)
		UAE_UbL	467..552	CDD:464286	34/85 (40%)
Uba2	NP_057891.1	Uba2_SUMO	19..442	CDD:238766	238/427 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..233		8/30 (27%)
		UAE_UbL	450..536	CDD:464286	38/86 (44%)
		UBA2_C	547..633	CDD:465058	25/87 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	548..638		25/91 (27%)