Protein Alignment Uba2 and uba2

DIOPT Version :10

• Sequence 1: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_009296132.1
• Gene: uba2 / 406672
• ZFINID: ZDB-GENE-040426-2681
• Length: 641
• Species: Danio rerio
• Alignment Length: 707
• Identity: 328/707 - (46%)
• Similarity: 442/707 - (62%)
• Gaps: 76/707 - (10%)

  Fly     3 AAINGVFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHR 67
            |.:.|.....|.:.:...:||||||||||||:||||||:||.:||:|||||||:|||||||||.:
Zfish     2 AELVGPLRKQLADSLSSCRVLVVGAGGIGCELLKNLVLTGFKNIEVIDLDTIDVSNLNRQFLFQK 66

  Fly    68 EHVGKSKARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCL 132
            :|||||||:||:||.|.|.|.|.|||||||:.:.||.|.||:.|.||::||||||||||||||||
Zfish    67 KHVGKSKAQVAKESVLRFCPSANITAYHDSIMNPDYNVEFFRNFQLVMNALDNRAARNHVNRMCL 131

  Fly   133 NADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAKHLFNQ 197
            .||:||||||||||.|||.:||:|.|:||||.||..|::|||||||||||||||||||||:||||
Zfish   132 AADIPLIESGTAGYLGQVTVIKKGQTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQ 196

  Fly   198 LFGESLEDEDISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANGNIMRINTRQ 262
            ||||...|:::|||.|||:|...         ..|...:...|.::         |:|.|::|::
Zfish   197 LFGEEDADQEVSPDTADPEAAWN---------PADAAARATASDQD---------GDIKRVSTKE 243

  Fly   263 WAKDCNYDAGKLFNKFFNEDITYLLRMSNLWKTRKAPVPVQWDTLLPEGSSGDQKDV---AKQHH 324
            ||:...||..|||||.|.:||.|||.|..|||.||||:|::|:.:  ...:|.|:.|   ..:..
Zfish   244 WARSTGYDPIKLFNKLFKDDIMYLLTMDKLWKKRKAPLPLEWEEI--NQLAGSQEQVIGSGLKDQ 306

  Fly   325 KVWSIEECAQVFANSLKELSANFLKLEGDDT-LAWDKDDQPAMDFVAACANVRSHIFDIERKSRF 388
            :|..::..||:|.:|::.|.:. ||.:||.. |.|||||.||||||.|.:|:|.::|.:..||||
Zfish   307 QVLGVQGYAQLFQHSVETLRSQ-LKEKGDGAELVWDKDDPPAMDFVTAASNLRMNVFSMNMKSRF 370

  Fly   389 EIKSMAGNIIPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPNARNHFLVPDASLPGPN 453
            ::||||||||||||||||:.||:.|:.|.|:|.:.:|||:.::...:||.|...||| .:|..||
Zfish   371 DVKSMAGNIIPAIATTNAVIAGLIVLEALKILNSDFEQCRTIFLNKQPNPRKKLLVP-CALDPPN 434

  Fly   454 PNCHVCASDPAITLKIDTKRMRIKELRDEVLVKTLNMLNPDVTVQ-SNGSILISSEEGETECNDG 517
            .:|:||||.|.:|:|::..:..::.|:|::|.:...|:.|||.:: ..|:|||||||||||.|:.
Zfish   435 ASCYVCASKPEVTVKLNVHKTMVQALQDKILKEKFGMVAPDVQIEDGKGTILISSEEGETEANNN 499

  Fly   518 KLLSELNIVDGVILKCDDFFQNYELSIIISHFDAERDENLFEVVADASQLKPKDEDQKEAVKDKE 582
            |.||:..|.:|..|:.|||.|:|.|.:.:.|.:....:..||||.||....|.....:|.
Zfish   500 KFLSDFGIRNGSRLQADDFLQDYTLLVNVIHSEELEKDVEFEVVGDAPDKAPAPSAPEEG----- 559

  Fly   583 DEPKSAKKRSTNGEGDSKDDGPSTSKRSRPNEVVEEDDDDCLVIEEDEDQADVVVVATDKLSVQS 647
                   |...||..||..  ||||.::    .||  |||.|:::.||:.:.         |...
Zfish   560 -------KNIANGNKDSAQ--PSTSSKA----AVE--DDDVLLVDSDEEPSS---------STMD 600

  Fly   648 PPKSGSKRKPCEVIEDEDITEILESSDDEPAGPTKCKRSRLD----DSNPVAVISID 700
            ...|..|||..:...|:                ...||.|||    |.:...:|::|
Zfish   601 TESSNRKRKHHDAETDD----------------ASSKRKRLDQQPADDDDEDIIALD 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	Uba2_SUMO	21..459	CDD:238766	246/441 (56%)
		UAE_UbL	467..552	CDD:464286	34/85 (40%)
uba2	XP_009296132.1	Uba2_SUMO	20..440	CDD:238766	246/441 (56%)
		UAE_UbL	448..534	CDD:464286	34/85 (40%)
		UBA2_C	545..628	CDD:465058	32/127 (25%)