DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba2 and Uba5

DIOPT Version :9

Sequence 1:	NP_524756.2	Gene:	Uba2 / 44496	FlyBaseID:	FBgn0029113	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_572722.2	Gene:	Uba5 / 32094	FlyBaseID:	FBgn0030305	Length:	404	Species:	Drosophila melanogaster

Alignment Length:	322	Identity:	71/322 - (22%)
Similarity:	120/322 - (37%)	Gaps:	89/322 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVAR 79
            |.::...|.:||.||:|......|...|...:.:.|.|.::|:|:||.| |..:..|.||...|.
  Fly    69 ERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLF-FTPDQAGLSKVAAAA 132

  Fly    80 ESALSFNPDAKITAYHDSVTSTDYGVNFFKKF---------------DLVLSALDNRAARNHVNR 129
            .:....|||.:|..::.::|:    |..|.:|               |||||.:||..||..:|.
  Fly   133 ATLSFINPDVEIETHNYNITT----VENFDRFLDTISQGGRIAGQPVDLVLSCVDNFEARMAINA 193

  Fly   130 MCLNADVPLIESGTA--GYNGQVELIKRGLTQCYECTP----------KDKQRS----------- 171
            .|...::...|||.:  ..:|.::.|:.|.|.|:.|.|          |..:|.
  Fly   194 ACNERNLNWFESGVSENAVSGHIQFIRPGDTACFACAPPLVVAENIDEKTLKREGVCAASLPTTM 258

  Fly   172 ---------------------------------FPGCTIRNTPS-EPIHCIVWAKHLFNQLFGES 202
                                             ||..|::..|. :..:|:|..|....:.....
  Fly   259 GITAGFLVQNALKYLLNFGEVSDYLGYNALSDFFPKMTLKPNPQCDDRNCLVRQKEFQARPKPVL 323

  Fly   203 LEDEDISPDAADP------DAKEKDGGDGNGEP-----KGDGKEKGEESKEE-KEAKEDTAN 252
            :|::.:|.:....      :...:|..:.|..|     .|:|.....|:.|: .|..|:|.:
  Fly   324 IEEKAVSEEPLHATNEWGIELVAEDAPESNTTPAETPVMGEGLRLAYEAPEKSSETSEETVS 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	54/232 (23%)
		Uba2_SUMO	21..459	CDD:238766	70/316 (22%)
		UAE_UbL	467..552	CDD:291402
		UBA2_C	573..691	CDD:292812
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	54/232 (23%)
Uba5	NP_572722.2	ThiF	53..310	CDD:279270	57/245 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446838
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10953
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840