Protein Alignment Uba2 and Uba2

DIOPT Version :10

• Sequence 1: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_001094049.1
• Gene: Uba2 / 308508
• RGDID: 1312023
• Length: 639
• Species: Rattus norvegicus
• Alignment Length: 674
• Identity: 323/674 - (47%)
• Similarity: 432/674 - (64%)
• Gaps: 66/674 - (9%)

  Fly    10 PPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSK 74
            |..|.|.|...:||||||||||||:||||||:||:.|::|||||||:|||||||||.::|||:||
  Rat     8 PRELAEAVSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSK 72

  Fly    75 ARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCLNADVPLI 139
            |:||:||.|.|:|.|.|.|:|||:.:.||.|.||::|.||::||||||||||||||||.||||||
  Rat    73 AQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 137

  Fly   140 ESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAKHLFNQLFGESLE 204
            |||||||.|||..||:|:|:||||.||..||:|||||||||||||||||||||:||||||||...
  Rat   138 ESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDA 202

  Fly   205 DEDISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANGNIMRINTRQWAKDCNY 269
            |:::|||.|||:|                  ..|.::.|..|:....:|:|.||:|::|||...|
  Rat   203 DQEVSPDRADPEA------------------AWEPTEAEARARASNEDGDIKRISTKEWAKSTGY 249

  Fly   270 DAGKLFNKFFNEDITYLLRMSNLWKTRKAPVPVQWDTLLPEG--SSGDQK---DVAKQHHKVWSI 329
            |..|||.|.|.:||.|||.|..||:.||.|||:.|..:..:|  ::.||:   .:..:..:|..:
  Rat   250 DPVKLFTKLFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEEANADQQSEPQLGLKDQQVLDV 314

  Fly   330 EECAQVFANSLKELSANFLKLEGDDT-LAWDKDDQPAMDFVAACANVRSHIFDIERKSRFEIKSM 393
            :..|.:|:.|::.|... |..:||.. |.|||||.||||||.:.||:|.|||.:..||||:||||
  Rat   315 KSYASLFSKSIETLRVR-LAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSM 378

  Fly   394 AGNIIPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPNARNHFLVPDASLPGPNPNCHV 458
            |||||||||||||:.||:.|:...|:|..|.:||:.::...:||.|...||| .:|..||.||:|
  Rat   379 AGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVP-CALDPPNTNCYV 442

  Fly   459 CASDPAITLKIDTKRMRIKELRDEVLVKTLNMLNPDVTVQ-SNGSILISSEEGETECNDGKLLSE 522
            |||.|.:|::::..::.:..|:|:::.:...|:.|||.:: ..|:|||||||||||.|:.|.||:
  Rat   443 CASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNPKKLSD 507

  Fly   523 LNIVDGVILKCDDFFQNYELSIIISHFDAERDENLFEVVADASQLKPKDEDQKEAVKDKEDEPKS 587
            ..|.:|..|:.|||.|:|.|.|.|.|.:....:..||||.|.        .:|...|..||..||
  Rat   508 FGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDT--------PEKVGPKQAEDAAKS 564

  Fly   588 AKKRSTNGEGDSKDDG--PSTSKRSRPNEVVEEDDDDCLVIEEDED---------QADVVVVATD 641
            .    .||    .|||  ||||        ..::.||.|:::.||:         :.|    .|.
  Rat   565 I----ANG----SDDGAQPSTS--------TAQEQDDVLIVDSDEEGPSNSADGSRDD----RTR 609

  Fly   642 KLSVQSPPKSGSKRKPCEVIEDED 665
            |..::....:.:|:...|.:||:|
  Rat   610 KRKLEENEGASTKKSRLEQVEDQD 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	Uba2_SUMO	21..459	CDD:238766	246/443 (56%)
		UAE_UbL	467..552	CDD:464286	34/85 (40%)
Uba2	NP_001094049.1	Uba2_SUMO	19..443	CDD:238766	239/429 (56%)
		UBA_E1_SCCH	179..361	CDD:463157	76/187 (41%)
		UAE_UbL	451..537	CDD:464286	37/86 (43%)
		UBA2_C	548..633	CDD:465058	25/95 (26%)