Protein Alignment Uba2 and Uba6

DIOPT Version :9

• Sequence 1: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_001100683.1
• Gene: Uba6 / 305268
• RGDID: 1308324
• Length: 1053
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 166/656 - (25%)
• Similarity: 260/656 - (39%)
• Gaps: 180/656 - (27%)

  Fly    12 TLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTD------IEIIDLDTIDLSNLNRQFLFHREHV 70
            ||.:.::...:.:||.|.||||:|||..|.|...      :.:.|.|.|:.|||||||||...|:
  Rat   453 TLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTGREKGMVTVTDPDLIEKSNLNRQFLFRPHHI 517

  Fly    71 GKSKARVARESALSFNPDAKITAYHDSV---TSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCL 132
            .|.|:..|.|:.|..||..||.|:.:.|   |.:.|...|:.|.|:|::||||..||.:|:..||
  Rat   518 QKPKSYTAAEATLKINPQLKIDAHLNKVCPATESTYSDEFYNKQDIVITALDNVEARRYVDSRCL 582

  Fly   133 NADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAKHLFNQ 197
            ....||::|||.|..|..|:|...||:.|.......:...|.||:::.|:...|.|.||:..|..
  Rat   583 ANLRPLLDSGTMGTKGHTEIIVPQLTESYNSHRDPPEEEIPFCTLKSFPAAVEHTIQWARDKFES 647

  Fly   198 LFGE--SLEDE--DISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANG----- 253
            .|..  ||.::  ...|.|.|...|.::|                          .:..|
  Rat   648 SFSHKPSLFNKFWQAYPSAEDVLQKIQNG--------------------------QSLEGCFQVI 686

  Fly   254 NIMRINTRQWAKDCNYDAGKLFNKFFNEDITYLLRM----------SNLWKT-RKAPVPVQWDTL 307
            .::....|.|:: |...|...|.|:||.....||..          |..|:: ::.|.|:::|..
  Rat   687 KLLSRRPRMWSQ-CVELARLKFEKYFNHKALQLLHCFPLDTRLKDGSLFWQSPKRPPSPIKFDLN 750

  Fly   308 LPEGSS----------------GDQKDVA----------------KQHHKVWSIEECAQ------ 334
            .|...|                ..:||::                |..:||...:|.|:
  Rat   751 EPLHLSFLQNAAKLYATVYCIPFSEKDLSVDSLMDILSEVKIQEFKPSNKVVQTDETARKPDHVP 815

  Fly   335 ---------VFANSLKELSANFLKLEGDD----TLAWDKDDQP--AMDFVAACANVRSHIFDIER 384
                     ||... |.||:|  |....|    .|:::|||..  .:||:.|.:|:|:.:::||.
  Rat   816 VSSEDERNAVFQLE-KALSSN--KATKSDLQMAVLSFEKDDDSNGHIDFITAASNLRAKMYNIEP 877

  Fly   385 KSRFEIKSMAGNIIPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPNARNHFLVPDASL 449
            ..||:.|.:||.|||||||:.|..:|:..:...||
  Rat   878 ADRFKTKRIAGKIIPAIATSTAAVSGLVALEMIKV------------------------------ 912

  Fly   450 PGPNP-----NCHVCASDPAITLKIDTKRMRIKELRDEV-----------------------LVK 486
            .|..|     ||.:..:.|.|.. .:|..:|..|:|:.:                       .||
  Rat   913 AGGYPFDAYKNCFLNLAIPIIVF-TETSEVRKTEIRNGISFTIWDRWTVHGKEDFTLSDFINAVK 976

  Fly   487 TLNMLNPDVTVQSNGSILISSEEGETECNDGKLLSELNIVDGVILKCDDFFQNYELSIIISHFDA 551
            ....:.|.:.||....:.:....|..:        .|.:....::|.....:..:|::..:. ||
  Rat   977 EKYGIEPTMVVQGVKMLYVPVMPGHAK--------RLKLTMHKLVKPSTEKKYVDLTVSFAP-DA 1032

  Fly   552 ERDENL 557
            :.||:|
  Rat  1033 DGDEDL 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	67/173 (39%)
		Uba2_SUMO	21..459	CDD:238766	144/524 (27%)
		UAE_UbL	467..552	CDD:291402	14/107 (13%)
		UBA2_C	573..691	CDD:292812
Uba6	NP_001100683.1	Ube1	38..1046	CDD:273603	166/656 (25%)
		Ube1_repeat1	43..428	CDD:238768
		E1_4HB	298..358	CDD:292809
		Ube1_repeat2	462..1005	CDD:238767	156/611 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810