DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba2 and MOCS3

DIOPT Version :9

Sequence 1:	NP_524756.2	Gene:	Uba2 / 44496	FlyBaseID:	FBgn0029113	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_055299.1	Gene:	MOCS3 / 27304	HGNCID:	15765	Length:	460	Species:	Homo sapiens

Alignment Length:	164	Identity:	46/164 - (28%)
Similarity:	77/164 - (46%)	Gaps:	12/164 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 VLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVARESALSFN 86
            ||:||.||:||.:.:.|..:|...:.::|.|.:::|||.||.|......|::||..|..|....|
Human    85 VLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLN 149

  Fly    87 PDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCLNADVPLIESGTAGYNGQVE 151
            ...:...|..::|... .::..:::|:|....||...|..||..|:.|..||:.:....:.||:.
Human   150 SAVECVPYTQALTPAT-ALDLVRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQIT 213

  Fly   152 LIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPI 185
            :.......||.|.       ||    :..|:|.:
Human   214 VYHYDGGPCYRCI-------FP----QPPPAETV 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	44/154 (29%)
		Uba2_SUMO	21..459	CDD:238766	46/164 (28%)
		UAE_UbL	467..552	CDD:291402
		UBA2_C	573..691	CDD:292812
MOCS3	NP_055299.1	ThiF_MoeB_HesA_family	62..285	CDD:238386	46/164 (28%)
MOCS3	NP_055299.1	RHOD_ThiF	327..460	CDD:238784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810