Protein Alignment Uba2 and uba3

DIOPT Version :10

• Sequence 1: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_592940.1
• Gene: uba3 / 2542099
• PomBaseID: SPAC24H6.12C
• Length: 444
• Species: Schizosaccharomyces pombe
• Alignment Length: 538
• Identity: 131/538 - (24%)
• Similarity: 202/538 - (37%)
• Gaps: 209/538 - (38%)

  Fly    10 PPTLQELVK---KSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVG 71
            |...:|.:|   .||:|::||||:|||:||:|.||||.|:.:||:||||::||||||||:..::.
pombe    32 PENPEETLKSAFSSKILIIGAGGLGCEILKDLALSGFRDLSVIDMDTIDITNLNRQFLFNESNID 96

  Fly    72 KSKARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVN----RMCL 132
            :.||.||....:...|...:|.::..:  .|..:.|:|:|.|::..||:..||..:|    .:..
pombe    97 EPKANVAASMIMKRIPSTVVTPFYGKI--QDKTIEFYKEFKLIICGLDSVEARRWINSTLVAIAK 159

  Fly   133 NAD-VPLIESGTAGYNGQVELIKRGLTQCYEC-----TPKDKQRSFPGCTIRNTPSEPIHCIVWA 191
            ..| :||::.|:.|..||..:|...:|.||||     |||   .|:|.||:.|||..|.||:.||
pombe   160 TGDLIPLVDGGSEGLKGQARVIIPTITSCYECSLDMLTPK---ISYPICTLANTPRLPEHCVEWA 221

  Fly   192 KHL-FNQLFGESLEDEDISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANGNI 255
            ..| :.::|..:..|.....:..:|    .||.:.|.||                       .||
pombe   222 YLLEWPRVFLNASVDSFSKQEVFEP----LDGKNSNFEP-----------------------DNI 259

  Fly   256 MRINTRQWAKDCNYDAGKLFNKFFNEDITYLLRMSNLWKTRKAPVPVQWDTLLPEGSSGDQKDVA 320
            ..|:                                 |..::
pombe   260 RHID---------------------------------WLVKR----------------------- 268

  Fly   321 KQHHKVWSIEECAQVFANSLKELSANFLKLEGDDTLAWDKDDQPAMDFVAACANVRSHIFDIERK 385
                   |||                                             |::.|.|...
pombe   269 -------SIE---------------------------------------------RANKFQIPSS 281

  Fly   386 S--RFEIKSMAGNIIPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPNARNHFLVPDAS 448
            |  ||.::.:...||||:|:||||.|......|.|:|                ...|.||.....
pombe   282 SINRFFVQGIVKRIIPAVASTNAIIAASCCNEALKIL----------------TESNPFLDNYMM 330

  Fly   449 LPGPN------------PNCHVC---------ASDPAITLKIDTKRMRIKELRDEVL---VKTLN 489
            ..|.:            .:|.||         ::...:|||             ::|   .|:.|
pombe   331 YVGEDGAYTYTFNLEKRSDCPVCGVLSEVYDISASSTVTLK-------------DILNHYSKSYN 382

  Fly   490 MLNPDVTVQSNGSILISS 507
            :.||.|:..:...:.::|
pombe   383 LQNPSVSTAAGTPLYLAS 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	Uba2_SUMO	21..459	CDD:238766	115/462 (25%)
		UAE_UbL	467..552	CDD:464286	9/44 (20%)
uba3	NP_592940.1	Uba3_RUB	46..354	CDD:238765	116/463 (25%)
		E2_bind	365..442	CDD:462611	10/49 (20%)