Protein Alignment Uba2 and uba-2

DIOPT Version :9

• Sequence 1: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_001293154.1
• Gene: uba-2 / 24104970
• WormBaseID: WBGene00006700
• Length: 582
• Species: Caenorhabditis elegans
• Alignment Length: 611
• Identity: 274/611 - (44%)
• Similarity: 378/611 - (61%)
• Gaps: 50/611 - (8%)

  Fly    15 ELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVAR 79
            |.:.:||:||:||||||||:||||.::||..:.:|||||||:|||||||||.:|||..|||..|.
 Worm     9 EKIVQSKILVIGAGGIGCELLKNLAVTGFRKVHVIDLDTIDISNLNRQFLFRKEHVSSSKAATAT 73

  Fly    80 ESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCLNADVPLIESGTA 144
            :....|.|..::|..|||:....|.:.||:.:|:||:|||||||||:|||||..|:.|||:||:.
 Worm    74 QVVKQFCPQIELTFDHDSIFEKKYNMEFFQAYDIVLNALDNRAARNYVNRMCHAANRPLIDSGSG 138

  Fly   145 GYNGQVELIKRGLTQCYECTPKD-KQRSFPGCTIRNTPSEPIHCIVWAKHLFNQLFGESLEDEDI 208
            ||.|||.:|.||.|:||||..|. :|.::|||||||||||.|||.|||||:|||||||...|:|:
 Worm   139 GYFGQVSVIMRGKTECYECVDKPVQQTTYPGCTIRNTPSEHIHCTVWAKHVFNQLFGEVDIDDDV 203

  Fly   209 SP--DAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEA-KEDTANGNIMRINTRQWAKDCNYD 270
            ||  ||.|||..|                 ...:::|||| ||:.|     .:.|||||:..:||
 Worm   204 SPDMDAVDPDNTE-----------------AVTTEKEKEAMKEEPA-----PVGTRQWAESVDYD 246

  Fly   271 AGKLFNKFFNEDITYLLRMSNLWKTRKAPVPVQWDTLLPEGSSGDQK---DVAKQHHKVWSIEEC 332
            |.|:|:|.|..||.||.:|.:|||.||.|.|:::.|....|  |:.:   |..:....:|::..|
 Worm   247 AAKVFDKLFLHDIEYLCKMEHLWKQRKRPSPLEFHTASSTG--GEPQSLCDAQRDDTSIWTLSTC 309

  Fly   333 AQVFANSLKELSANFLKLEGDDTLAWDKDDQPAMDFVAACANVRSHIFDIERKSRFEIKSMAGNI 397
            |:||:..::||... ::.|.|..||:|||....|.|||||||:|:.||.|..||:|:||:|||||
 Worm   310 AKVFSTCIQELLEQ-IRAEPDVKLAFDKDHAIIMSFVAACANIRAKIFGIPMKSQFDIKAMAGNI 373

  Fly   398 IPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPNARNHFLVPDASLPGPNPNCHVCASD 462
            |||||:||||.|||.|..|.:|:|.....|.:..|..:.|.|......||:.| |||.|.||:..
 Worm   374 IPAIASTNAIVAGIIVTEAVRVIEGSTVICNSSIATTQSNPRGRIFGGDATNP-PNPRCFVCSEK 437

  Fly   463 PAITLKIDTKRMRIKELRDEVLVKTLNMLNPDVTVQSNGSILISSEEGETECNDGKLLSELNIVD 527
            ..:.:.::...|.:..|.::||.:.||||.|||...:...|::|| :|:|:....|.|:|::|.|
 Worm   438 REVFIYVNPDTMTVGGLCEKVLKQKLNMLAPDVMDSATSRIIVSS-DGDTDDLLPKKLAEVSIED 501

  Fly   528 GVILKCDDFFQNYELSIIISHFDAERDENLFEVVADASQLKPKDEDQKEAVKDKEDEPKSAKKRS 592
            |.||.||||.|..|:.:.|...|....:: |||.  .|:.:|:.:|:|... |..:||::.:::.
 Worm   502 GAILSCDDFQQEMEIKLFIKKGDRLAGDD-FEVA--RSEKEPEPDDRKRKA-DGSEEPEAKRQKV 562

  Fly   593 TNGEGDSKDDGPSTSKRSRPNEVVEE 618
                 :.|||       ...||.|.|
 Worm   563 -----EEKDD-------KNGNEAVAE 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	92/162 (57%)
		Uba2_SUMO	21..459	CDD:238766	221/444 (50%)
		UAE_UbL	467..552	CDD:291402	32/84 (38%)
		UBA2_C	573..691	CDD:292812	12/46 (26%)
uba-2	NP_001293154.1	ThiF	9..>172	CDD:279270	92/162 (57%)
		E1_enzyme_family	15..434	CDD:304554	221/444 (50%)
		UAE_UbL	442..526	CDD:291402	32/84 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167181
Domainoid	1	1.000	400	1.000	Domainoid score	I372
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	479	1.000	Inparanoid score	I810
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54272
OrthoDB	1	1.010	-	-		D436007at33208
OrthoFinder	1	1.000	-	-		FOG0004682
OrthoInspector	1	1.000	-	-		oto17695
orthoMCL	1	0.900	-	-		OOG6_101769
Panther	1	1.100	-	-	LDO	PTHR10953
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2782
SonicParanoid	1	1.000	-	-		X3290
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800